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Shridhar Bhat - Publications

Affiliations: 
Pharmacology Johns Hopkins University School of Medicine, Baltimore, MD, United States 
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Egleston M, Dong L, Howlader AH, Bhat S, Orris B, Bianchet MA, Greenberg MM, Stivers JT. Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding. Acs Chemical Biology. PMID 37233733 DOI: 10.1021/acschembio.3c00118  0.386
2019 Rodriguez G, Orris B, Majumdar A, Bhat S, Stivers JT. Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2. Dna Repair. 86: 102764. PMID 31855846 DOI: 10.1016/J.Dnarep.2019.102764  0.333
2018 Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, et al. Rapamycin-inspired macrocycles with new target specificity. Nature Chemistry. PMID 30532015 DOI: 10.1038/S41557-018-0187-4  0.685
2018 Bhat S, Hwang Y, Gibson MD, Morgan MT, Taverna SD, Zhao Y, Wolberger C, Poirier MG, Cole PA. Hydrazide Mimics for Protein Lysine Acylation to Assess Nucleosome Dynamics and Deubiquitinase Action. Journal of the American Chemical Society. PMID 29991262 DOI: 10.1021/Jacs.8B03572  0.342
2018 Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating JRPM. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Research. PMID 29807040 DOI: 10.1016/J.Antiviral.2018.05.010  0.794
2013 Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z  0.786
2013 Bhat S, Shim JS, Liu JO. Tricyclic thiazoles are a new class of angiogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 2733-7. PMID 23518276 DOI: 10.1016/J.Bmcl.2013.02.067  0.667
2013 Zhang P, Yang X, Zhang F, Gabelli SB, Wang R, Zhang Y, Bhat S, Chen X, Furlani M, Amzel LM, Liu JO, Ma D. Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorganic & Medicinal Chemistry. 21: 2600-17. PMID 23507151 DOI: 10.1016/J.Bmc.2013.02.023  0.772
2012 Krátký M, Vinšová J, Novotná E, Mandíková J, Wsól V, Trejtnar F, Ulmann V, Stolaříková J, Fernandes S, Bhat S, Liu JO. Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase. Tuberculosis (Edinburgh, Scotland). 92: 434-9. PMID 22765970 DOI: 10.1016/J.Tube.2012.06.001  0.477
2012 Bhat S, Olaleye O, Meyer KJ, Shi W, Zhang Y, Liu JO. Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. Bioorganic & Medicinal Chemistry. 20: 4507-13. PMID 22704656 DOI: 10.1016/J.Bmc.2012.05.022  0.721
2012 Bhat S, Shim JS, Zhang F, Chong CR, Liu JO. Substituted oxines inhibit endothelial cell proliferation and angiogenesis. Organic & Biomolecular Chemistry. 10: 2979-92. PMID 22391578 DOI: 10.1039/C2Ob06978D  0.802
2012 Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. The Journal of Antimicrobial Chemotherapy. 67: 398-403. PMID 22160146 DOI: 10.1093/Jac/Dkr496  0.367
2011 Olaleye O, Raghunand TR, Bhat S, Chong C, Gu P, Zhou J, Zhang Y, Bishai WR, Liu JO. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: S61-5. PMID 22115541 DOI: 10.1016/J.Tube.2011.10.012  0.793
2011 Hoveyda HR, Marsault E, Gagnon R, Mathieu AP, Vézina M, Landry A, Wang Z, Benakli K, Beaubien S, Saint-Louis C, Brassard M, Pinault JF, Ouellet L, Bhat S, Ramaseshan M, et al. Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic. Journal of Medicinal Chemistry. 54: 8305-20. PMID 22106937 DOI: 10.1021/Jm2007062  0.334
2011 Chamni S, He QL, Dang Y, Bhat S, Liu JO, Romo D. Diazo reagents with small steric footprints for simultaneous arming/SAR studies of alcohol-containing natural products via O-H insertion. Acs Chemical Biology. 6: 1175-81. PMID 21894934 DOI: 10.1021/Cb2002686  0.776
2011 Li W, Bhat S, Liu JO. A simple and efficient route to the FKBP-binding domain from rapamycin. Tetrahedron Letters. 52: 5070-5072. PMID 21894238 DOI: 10.1016/J.Tetlet.2011.07.094  0.475
2011 Dang Y, Schneider-Poetsch T, Eyler DE, Jewett JC, Bhat S, Rawal VH, Green R, Liu JO. Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B. Rna (New York, N.Y.). 17: 1578-88. PMID 21693620 DOI: 10.1261/Rna.2624511  0.794
2011 Titov DV, Gilman B, He QL, Bhat S, Low WK, Dang Y, Smeaton M, Demain AL, Miller PS, Kugel JF, Goodrich JA, Liu JO. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nature Chemical Biology. 7: 182-8. PMID 21278739 DOI: 10.1038/Nchembio.522  0.795
2010 Shi W, Nacev BA, Bhat S, Liu JO. Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole. Acs Medicinal Chemistry Letters. 1: 155-159. PMID 21892383 DOI: 10.1021/Ml1000068  0.727
2010 Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. Journal of the National Cancer Institute. 102: 1855-73. PMID 21088277 DOI: 10.1093/Jnci/Djq457  0.776
2010 Olaleye O, Raghunand TR, Bhat S, He J, Tyagi S, Lamichhane G, Gu P, Zhou J, Zhang Y, Grosset J, Bishai WR, Liu JO. Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets. Chemistry & Biology. 17: 86-97. PMID 20142044 DOI: 10.1016/J.Chembiol.2009.12.014  0.727
2010 Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nature Chemical Biology. 6: 209-217. PMID 20118940 DOI: 10.1038/Nchembio.304  0.805
2010 Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin Nature Chemical Biology. 6: 209-217. DOI: 10.1038/nchembio.304  0.374
2009 Liu JO, Nacev BA, Xu J, Bhat S. It takes two binding sites for calcineurin and NFAT to tango. Molecular Cell. 33: 676-8. PMID 19328062 DOI: 10.1016/J.Molcel.2009.03.005  0.705
2009 Chen X, Xie S, Bhat S, Kumar N, Shapiro TA, Liu JO. Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chemistry & Biology. 16: 193-202. PMID 19246010 DOI: 10.1016/J.Chembiol.2009.01.006  0.677
2008 Marsault E, Hoveyda HR, Gagnon R, Peterson ML, Vézina M, Saint-Louis C, Landry A, Pinault JF, Ouellet L, Beauchemin S, Beaubien S, Mathieu A, Benakli K, Wang Z, Brassard M, ... ... Bhat S, et al. Efficient parallel synthesis of macrocyclic peptidomimetics. Bioorganic & Medicinal Chemistry Letters. 18: 4731-5. PMID 18640834 DOI: 10.1016/J.Bmcl.2008.06.085  0.302
2007 Low WK, Dang Y, Bhat S, Romo D, Liu JO. Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity. Chemistry & Biology. 14: 715-27. PMID 17584618 DOI: 10.1016/J.Chembiol.2007.05.012  0.697
2007 McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio CL. The HBV drug entecavir - effects on HIV-1 replication and resistance. The New England Journal of Medicine. 356: 2614-21. PMID 17582071 DOI: 10.1056/Nejmoa067710  0.665
2007 Chong CR, Xu J, Lu J, Bhat S, Sullivan DJ, Liu JO. Inhibition of angiogenesis by the antifungal drug itraconazole. Acs Chemical Biology. 2: 263-70. PMID 17432820 DOI: 10.1021/Cb600362D  0.761
2006 Brockhausen I, Benn M, Bhat S, Marone S, Riley JG, Montoya-Peleaz P, Vlahakis JZ, Paulsen H, Schutzbach JS, Szarek WA. UDP-Gal: GlcNAc-R beta1,4-galactosyltransferase--a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme. Glycoconjugate Journal. 23: 525-41. PMID 17006644 DOI: 10.1007/S10719-006-7153-X  0.391
2004 Kisilevsky R, Szarek WA, Ancsin JB, Elimova E, Marone S, Bhat S, Berkin A. Inhibition of amyloid A amyloidogenesis in vivo and in tissue culture by 4-deoxy analogues of peracetylated 2-acetamido-2-deoxy-alpha- and beta-d-glucose: implications for the treatment of various amyloidoses. The American Journal of Pathology. 164: 2127-37. PMID 15161647 DOI: 10.1016/S0002-9440(10)63771-6  0.353
2003 Kisilevsky R, Szarek WA, Ancsin J, Bhat S, Li Z, Marone S. Novel glycosaminoglycan precursors as anti-amyloid agents, part III. Journal of Molecular Neuroscience : Mn. 20: 291-7. PMID 14501011 DOI: 10.1385/Jmn:20:3:291  0.375
2002 Kisilevsky R, Crandall I, Szarek WA, Bhat S, Tan C, Boudreau L, Kain KC. Short-chain aliphatic polysulfonates inhibit the entry of Plasmodium into red blood cells. Antimicrobial Agents and Chemotherapy. 46: 2619-26. PMID 12121942 DOI: 10.1128/Aac.46.8.2619-2626.2002  0.373
2000 Bhat S, Vaino AR, Szarek WA. Targeting of phosphonoacetate to the liver: Synthesis of a phosphonoacetate-trilactoside conjugate Israel Journal of Chemistry. 40: 335-341. DOI: 10.1560/8Qka-Dfyf-Fj70-E1Cx  0.316
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