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Laurence E. Cheng, Ph.D. - Publications

Affiliations: 
2002 University of Washington, Seattle, Seattle, WA 
Area:
Immunology
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Abuqayyas L, Cheng L, Mitragotri D, Smith S, Santos MTD, Zhou Y, Chindalore V, Cohen S, Kivitz A, Posch M, Sullivan B, Parnes J. Fri0084 Safety, Pharmacokinetics, Pharmacodynamics, Immunogenicity, And Preliminary Efficacy Of Rozibafusp Alfa In Subjects With Rheumatoid Arthritis: Interim Analysis Of A Phase 1B Randomized, Placebo-Controlled, Multiple Ascending Dose Clinical Trial Annals of the Rheumatic Diseases. 79: 619-620. DOI: 10.1136/Annrheumdis-2020-Eular.4744  0.305
2019 Cheng LE, Hsu H, Kankam M, Siebers N, Stoltz R, Abuqayyas L, Ertik B, Sullivan B, Zhou L, Parnes JR. 290 Development and first-in-human characterization of an ICOSL and BAFF bispecific inhibitor AMG 570 for SLE treatment Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.290  0.359
2018 Cheng LE, Amoura Z, Cheah B, Hiepe F, Sullivan BA, Zhou L, Arnold GE, Tsuji WH, Merrill JT, Chung JB. A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled, Multiple-Dose Study to Evaluate AMG 557 in Patients With Systemic Lupus Erythematosus and Active Lupus Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29513931 DOI: 10.1002/Art.40479  0.302
2018 Cheng LE, Kankam M, Siebers N, Stoltz R, Abuqayyas L, Ertik B, Sullivan BA, Zhou L, Mitragotri D, Parnes JR. AB0521 Safety, pharmacokinetics, and pharmacodynamics of single doses of a bispecific icosl and baff inhibitor, amg 570, in healthy subjects Annals of the Rheumatic Diseases. 77: 1418-1418. DOI: 10.1136/Annrheumdis-2018-Eular.2956  0.366
2015 Ahmed A, Reith W, Puck JM, Cheng LE. Novel Mutation in the Class II Transactivator Associated with Immunodeficiency and Autoimmunity. Journal of Clinical Immunology. 35: 521-2. PMID 26271388 DOI: 10.1007/S10875-015-0183-Z  0.398
2015 Bose O, Baluk P, Looney MR, Cheng LE, McDonald DM, Caughey GH, Krummel MF. Mast cells present protrusions into blood vessels upon tracheal allergen challenge in mice. Plos One. 10: e0118513. PMID 25789765 DOI: 10.1371/Journal.Pone.0118513  0.327
2015 Cheng LE, Sullivan BM, Retana LE, Allen CD, Liang HE, Locksley RM. IgE-activated basophils regulate eosinophil tissue entry by modulating endothelial function. The Journal of Experimental Medicine. 212: 513-24. PMID 25779634 DOI: 10.1084/Jem.20141671  0.373
2015 Cheng LE, Locksley RM. Allergic inflammation--innately homeostatic. Cold Spring Harbor Perspectives in Biology. 7: a016352. PMID 25414367 DOI: 10.1101/Cshperspect.A016352  0.301
2013 Nussbaum JC, Van Dyken SJ, von Moltke J, Cheng LE, Mohapatra A, Molofsky AB, Thornton EE, Krummel MF, Chawla A, Liang HE, Locksley RM. Type 2 innate lymphoid cells control eosinophil homeostasis. Nature. 502: 245-8. PMID 24037376 DOI: 10.1038/Nature12526  0.379
2013 Molofsky AB, Nussbaum JC, Liang HE, Van Dyken SJ, Cheng LE, Mohapatra A, Chawla A, Locksley RM. Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages. The Journal of Experimental Medicine. 210: 535-49. PMID 23420878 DOI: 10.1084/Jem.20121964  0.327
2013 Cheng LE, Hartmann K, Roers A, Krummel MF, Locksley RM. Perivascular mast cells dynamically probe cutaneous blood vessels to capture immunoglobulin E. Immunity. 38: 166-75. PMID 23290520 DOI: 10.1016/J.Immuni.2012.09.022  0.385
2012 Hanson E, Zilberman-Rudenko J, Cheng L, Ashwell J, Siegel R, Orange J. P085 Skewed binding of linear ubiquitin chains underlies inflammatory pathology in NEMO syndrome Cytokine. 59: 546-547. DOI: 10.1016/J.Cyto.2012.06.173  0.344
2011 Sullivan BM, Liang HE, Bando JK, Wu D, Cheng LE, McKerrow JK, Allen CD, Locksley RM. Genetic analysis of basophil function in vivo. Nature Immunology. 12: 527-35. PMID 21552267 DOI: 10.1038/Ni.2036  0.516
2010 Cheng LE, Wang ZE, Locksley RM. Murine B cells regulate serum IgE levels in a CD23-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 185: 5040-7. PMID 20870945 DOI: 10.4049/Jimmunol.1001900  0.447
2007 Cheng L, Greenberg P. Delivery Of Augmented Il-2 Receptor Signals To Cd8+ T Cells Replaces The Requirement For Helper Function In The Generation Of Primary But Not Secondary Cd8+ T Cell Responses Journal of Allergy and Clinical Immunology. 119: S92. DOI: 10.1016/J.Jaci.2006.11.386  0.642
2002 Cheng LE, Greenberg PD. Selective delivery of augmented IL-2 receptor signals to responding CD8+ T cells increases the size of the acute antiviral response and of the resulting memory T cell pool. Journal of Immunology (Baltimore, Md. : 1950). 169: 4990-7. PMID 12391213 DOI: 10.4049/Jimmunol.169.9.4990  0.645
2002 Blattman JN, Cheng LE, Greenberg PD. CD8(+) T cell responses: it's all downhill after their prime. Nature Immunology. 3: 601-2. PMID 12087413 DOI: 10.1038/Ni0702-601  0.636
2002 Ohlén C, Kalos M, Cheng LE, Shur AC, Hong DJ, Carson BD, Kokot NC, Lerner CG, Sather BD, Huseby ES, Greenberg PD. CD8(+) T cell tolerance to a tumor-associated antigen is maintained at the level of expansion rather than effector function. The Journal of Experimental Medicine. 195: 1407-18. PMID 12045239 DOI: 10.1084/Jem.20011063  0.637
2002 Cheng LE, Ohlén C, Nelson BH, Greenberg PD. Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death. Proceedings of the National Academy of Sciences of the United States of America. 99: 3001-6. PMID 11867736 DOI: 10.1073/Pnas.052676899  0.628
1995 Chan FK, Zhang J, Cheng L, Shapiro DN, Winoto A. Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. Molecular and Cellular Biology. 15: 2682-8. PMID 7739548 DOI: 10.1128/Mcb.15.5.2682  0.323
1995 Woronicz JD, Lina A, Calnan BJ, Szychowski S, Cheng L, Winoto A. Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis. Molecular and Cellular Biology. 15: 6364-76. PMID 7565789 DOI: 10.1128/Mcb.15.11.6364  0.333
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