FK Stevenson - Publications

Affiliations: 
Biochemistry University of Oxford, Oxford, United Kingdom 

8/295 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Pop LM, Smallshaw JE, Tucker TF, Stevenson FK, Vitetta ES. Failure of vaccination with idiotypic protein or DNA, (+/-IL-2), the depletion of regulatory T cells, or the blockade of CTLA-4 to prolong dormancy in mice with BCL1 lymphoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 28: 525-34. PMID 16224269  0.308
2005 Savelyeva N, King CA, Vitetta ES, Stevenson FK. Inhibition of a vaccine-induced anti-tumor B cell response by soluble protein antigen in the absence of continuing T cell help. Proceedings of the National Academy of Sciences of the United States of America. 102: 10987-92. PMID 16037207 DOI: 10.1073/pnas.0505108102  0.333
2001 Savelyeva N, Munday R, Spellerberg MB, Lomonossoff GP, Stevenson FK. Plant viral genes in DNA idiotypic vaccines activate linked CD4+ T-cell mediated immunity against B-cell malignancies. Nature Biotechnology. 19: 760-4. PMID 11479570 DOI: 10.1038/90816  0.323
1995 Stevenson FK, Zhu D, King CA, Ashworth LJ, Kumar S, Thompsett A, Hawkins RE. A genetic approach to idiotypic vaccination for B cell lymphoma Annals of the New York Academy of Sciences. 772: 212-226. PMID 8546396 DOI: 10.1111/j.1749-6632.1995.tb44747.x  0.31
1994 Hawkins RE, Zhu D, Ovecka M, Winter G, Hamblin TJ, Long A, Stevenson FK. Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines Blood. 83: 3279-3288. PMID 8193363  0.308
1993 King CA, Wills MR, Hamblin TJ, Stevenson FK. Idiotypic IgM on a B-cell surface requires processing for recognition by anti-idiotypic T cells. Cellular Immunology. 147: 411-24. PMID 8095858 DOI: 10.1006/cimm.1993.1080  0.302
1976 Hough DW, Eady RP, Hamblin TJ, Stevenson FK, Stevenson GT. Anti-idiotype sera raised against surface immunoglobulin of human neoplastic lymphocytes. The Journal of Experimental Medicine. 144: 960-9. PMID 62018 DOI: 10.1084/jem.144.4.960  0.307
1969 Kent PW, Molineux IJ, Haegele MR, Stevenson FK. Protein-polysaccharide complexes secreted by the calf tracheal epithelium in vitro Biochemical Journal. 114: 87P. PMID 5343805  0.376
Low-probability matches (unlikely to be authored by this person)
2004 Stevenson FK, Caligaris-Cappio F. Chronic lymphocytic leukemia: revelations from the B-cell receptor. Blood. 103: 4389-95. PMID 14962897 DOI: 10.1182/blood-2003-12-4312  0.299
1997 Bhat NM, Bieber MM, Hsu FJ, Chapman CJ, Spellerberg M, Stevenson FK, Teng NNH. Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies, II Clinical and Experimental Immunology. 108: 151-159. PMID 9097924 DOI: 10.1046/j.1365-2249.1997.d01-976.x  0.298
1994 Sahota S, Hamblin T, Oscier DG, Stevenson FK. Assessment of the role of clonogenic B lymphocytes in the pathogenesis of multiple myeloma. Leukemia. 8: 1285-9. PMID 8057663  0.297
2004 Stevenson FK, King A, Ottensmeier CH. Vaccine therapy in NHL: future promises and current limitations. Leukemia & Lymphoma. S85-90. PMID 15202530 DOI: 10.1080/10428190310001623711  0.296
1998 Sahota SS, Garand R, Bataille R, Smith AJ, Stevenson FK. VH gene analysis of clonally related IgM and IgG from human lymphoplasmacytoid B-cell tumors with chronic lymphocytic leukemia features and high serum monoclonal IgG. Blood. 91: 238-43. PMID 9414290  0.295
1993 Chapman CJ, Spellerberg MB, Smith GA, Carter SJ, Hamblin TJ, Stevenson FK. Autoanti-red cell antibodies synthesized by patients with infectious mononucleosis utilize the VH4-21 gene segment. Journal of Immunology (Baltimore, Md. : 1950). 151: 1051-61. PMID 8393034  0.295
1990 Wilson A, George AJT, King CA, Stevenson FK. Recognition of a B cell lymphoma by antmdiotypic T cells Journal of Immunology. 145: 3937-3943. PMID 2246520  0.295
1997 Spellerberg MB, Zhu D, Thompsett A, King CA, Hamblin TJ, Stevenson FK. DNA vaccines against lymphoma: promotion of anti-idiotypic antibody responses induced by single chain Fv genes by fusion to tetanus toxin fragment C. Journal of Immunology (Baltimore, Md. : 1950). 159: 1885-92. PMID 9257853  0.293
2000 Stevenson FK, King CA, Spellerberg MB, Zhu D, Rice J, Sahota S, Thompsett A, Radl J, Hamblin TJ. DNA vaccines against haematological malignancies. Haematologica. 11-3. PMID 10907456  0.291
2004 Stevenson FK, Ottensmeier CH, Johnson P, Zhu D, Buchan SL, McCann KJ, Roddick JS, King AT, McNicholl F, Savelyeva N, Rice J. DNA vaccines to attack cancer. Proceedings of the National Academy of Sciences of the United States of America. 101: 14646-52. PMID 15292504 DOI: 10.1073/pnas.0404896101  0.291
1993 Stevenson FK, Spellerberg MB, Treasure J, Chapman CJ, Silberstein LE, Hamblin TJ, Jones DB. Differential usage of an Ig heavy chain variable region gene by human B-cell tumors. Blood. 82: 224-30. PMID 8324224  0.29
1989 Stevenson FK, Smith GJ, North J, Hamblin TJ, Glennie MJ. Identification of normal B-cell counterparts of neoplastic cells which secrete cold agglutinins of anti-I and anti-i specificity. British Journal of Haematology. 72: 9-15. PMID 2472169 DOI: 10.1111/j.1365-2141.1989.tb07643.x  0.289
1993 Hawkins RE, Winter G, Hamblin TJ, Stevenson FK, Russell SJ. A genetic approach to idiotypic vaccination Journal of Immunotherapy. 14: 273-278. PMID 8280708 DOI: 10.1097/00002371-199311000-00004  0.289
1984 Stevenson FK, Glennie MJ, Johnston DM, Tutt AL, Stevenson GT. Consumption of monoclonal anti-idiotypic antibody by neoplastic B lymphocytes: a guide for immunotherapy. British Journal of Cancer. 50: 407-13. PMID 6380556 DOI: 10.1038/bjc.1984.190  0.289
1998 King CA, Spellerberg MB, Zhu D, Rice J, Sahota SS, Thompsett AR, Hamblin TJ, Radl J, Stevenson FK. DNA vaccines with single-chain Fv fused to fragment C of tetanus toxin induce protective immunity against lymphoma and myeloma. Nature Medicine. 4: 1281-6. PMID 9809552 DOI: 10.1038/3266  0.286
2022 Minton AR, Smith LD, Bryant DJ, Strefford JC, Forconi F, Stevenson FK, Tumbarello DA, James E, Løset GÅ, Munthe LA, Steele AJ, Packham G. B-cell receptor dependent phagocytosis and presentation of particulate antigen by chronic lymphocytic leukemia cells. Exploration of Targeted Anti-Tumor Therapy. 3: 37-49. PMID 35309250 DOI: 10.37349/etat.2022.00070  0.284
1995 Zhu D, Oscier DG, Stevenson FK. Splenic lymphoma with villous lymphocytes involves B cells with extensively mutated Ig heavy chain variable region genes. Blood. 85: 1603-7. PMID 7888678  0.283
1985 Tutt AL, Stevenson FK, Slavin S, Stevenson GT. Secretion of idiotypic IgM by the mouse B-cell leukaemia (BCL1) occurs spontaneously in vitro and in vivo. Immunology. 55: 59-63. PMID 3873405  0.281
1981 Stevenson FK, Hamblin TJ, Stevenson GT, Tutt AL. Extracellular idiotypic immunoglobulin arising from human leukemic B lymphocytes. The Journal of Experimental Medicine. 152: 1484-96. PMID 6969771 DOI: 10.1084/jem.152.6.1484  0.28
1988 George AJ, Spellerberg MB, Stevenson FK. Idiotype vaccination leads to the emergence of a stable surface Ig-negative variant of the mouse lymphoma BCL1, with different growth characteristics. Journal of Immunology (Baltimore, Md. : 1950). 140: 1695-701. PMID 3162250  0.279
1991 Smith GJ, Spellerberg MB, North J, Hamblin TJ, Stevenson FK. Isolation and EBV-transformation of a minor population of normal human tonsillar B cells bearing a cold agglutinin-associated idiotope. Journal of Autoimmunity. 3: 759-71. PMID 1965123 DOI: 10.1016/s0896-8411(05)80042-3  0.278
2018 Küppers R, Stevenson FK. Critical influences on the pathogenesis of follicular lymphoma. Blood. 131: 2297-2306. PMID 29666116 DOI: 10.1182/blood-2017-11-764365  0.278
2002 Forconi F, King CA, Sahota SS, Kennaway CK, Russell NH, Stevenson FK. Insight into the potential for DNA idiotypic fusion vaccines designed for patients by analysing xenogeneic anti-idiotypic antibody responses. Immunology. 107: 39-45. PMID 12225361  0.278
1999 Thomas MD, Clough K, Melamed MD, Stevenson FK, Chapman CJ, Spellerberg MB, Potter KN, Newton-Bishop JA, Gregson N, Dawson K. A human monoclonal antibody encoded by the V4-34 gene segment recognises melanoma-associated ganglioside via CDR3 and FWR1. Human Antibodies. 9: 95-106. PMID 10405830  0.277
1983 Stevenson FK, Gordon J. Immunization with idiotypic immunoglobulin protects against development of B lymphocytic leukemia, but emerging tumor cells can evade antibody attack by modulation. Journal of Immunology (Baltimore, Md. : 1950). 130: 970-3. PMID 6600259  0.277
1990 Stevenson FK, George AJ, Glennie MJ. Anti-idiotypic therapy of leukemias and lymphomas. Chemical Immunology. 48: 126-66. PMID 2403803  0.276
1985 Gregg EO, Al-Saffar N, Jones DB, Wright DH, Stevenson FK, Smith JL. Immunoglobulin negative follicle centre cell lymphoma. British Journal of Cancer. 50: 735-44. PMID 6437429 DOI: 10.1038/bjc.1984.250  0.276
2012 Stevenson FK, Stevenson GT. Follicular lymphoma and the immune system: from pathogenesis to antibody therapy. Blood. 119: 3659-67. PMID 22337721 DOI: 10.1182/blood-2011-11-367730  0.275
1989 Stevenson FK, Stevenson GT. Therapeutic strategies for B cell malignancies involving idiotype-anti-idiotype interactions. International Reviews of Immunology. 1: 303-33. PMID 3334051 DOI: 10.3109/08830188609056611  0.273
2002 Thirdborough SM, Radcliffe JN, Friedmann PS, Stevenson FK. Vaccination with DNA encoding a single-chain TCR fusion protein induces anticlonotypic immunity and protects against T-cell lymphoma. Cancer Research. 62: 1757-60. PMID 11912151  0.272
1997 Sahota SS, Leo R, Hamblin TJ, Stevenson FK. Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells. Blood. 89: 219-26. PMID 8978295  0.272
2008 Rice J, Dossett ML, Ohlén C, Buchan SL, Kendall TJ, Dunn SN, Stevenson FK, Greenberg PD. DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire. European Journal of Immunology. 38: 2118-30. PMID 18624299 DOI: 10.1002/Eji.200838213  0.271
1999 Stevenson FK, Sahota SS. B cell maturation in relation to multiple myeloma. Pathologie-Biologie. 47: 89-97. PMID 10192875  0.271
1986 Stevenson FK, Wrightham M, Glennie MJ, Jones DB, Cattan AR, Feizi T, Hamblin TJ, Stevenson GT. Antibodies to shared idiotypes as agents for analysis and therapy for human B cell tumors. Blood. 68: 430-6. PMID 2425869  0.27
1995 Stevenson FK, Spellerberg MB, Chapman CJ, Hamblin TJ. Differential usage of an autoantibody-associated VH gene, VH4-21, by human B-cell tumors. Leukemia & Lymphoma. 16: 379-84. PMID 7787747 DOI: 10.3109/10428199509054423  0.27
2000 Stevenson FK. DNA vaccines against cancer: from genes to therapy. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 10: 1413-8. PMID 10643531 DOI: 10.1023/a:1008395012716  0.268
2007 Radcliffe CM, Arnold JN, Suter DM, Wormald MR, Harvey DJ, Royle L, Mimura Y, Kimura Y, Sim RB, Inogès S, Rodriguez-Calvillo M, Zabalegui N, de Cerio AL, Potter KN, Mockridge CI, ... ... Stevenson FK, et al. Human follicular lymphoma cells contain oligomannose glycans in the antigen-binding site of the B-cell receptor. The Journal of Biological Chemistry. 282: 7405-15. PMID 17197448 DOI: 10.1074/Jbc.M602690200  0.268
2005 Sahota SS, Townsend M, Stevenson FK. Identification and assembly of V genes as idiotype-specific DNA fusion vaccines in multiple myeloma. Methods in Molecular Medicine. 113: 105-19. PMID 15968098 DOI: 10.1385/1-59259-916-8:105  0.266
2014 Stevenson FK, Forconi F, Packham G. The meaning and relevance of B-cell receptor structure and function in chronic lymphocytic leukemia. Seminars in Hematology. 51: 158-67. PMID 25048780 DOI: 10.1053/j.seminhematol.2014.05.003  0.266
2010 Coelho V, Krysov S, Ghaemmaghami AM, Emara M, Potter KN, Johnson P, Packham G, Martinez-Pomares L, Stevenson FK. Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins. Proceedings of the National Academy of Sciences of the United States of America. 107: 18587-92. PMID 20937880 DOI: 10.1073/Pnas.1009388107  0.266
2021 Chiodin G, Allen JD, Bryant D, Rock P, Martino EA, Valle-Argos B, Duriez PJ, Watanabe Y, Henderson I, Blachly JS, McCann KJ, Strefford JC, Packham G, Geijtenbeek TB, Figdor C, ... ... Stevenson FK, et al. Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior. Blood. PMID 34424958 DOI: 10.1182/blood.2021012052  0.266
1996 Fais F, Sellars B, Ghiotto F, Yan XJ, Dono M, Allen SL, Budman D, Dittmar K, Kolitz J, Lichtman SM, Schulman P, Schuster M, Vinciguerra VP, Rai K, Stevenson FK, et al. Examples of in vivo isotype class switching in IgM+ chronic lymphocytic leukemia B cells. The Journal of Clinical Investigation. 98: 1659-66. PMID 8833916 DOI: 10.1172/JCI118961  0.264
1987 George AJ, Tutt AL, Stevenson FK. Anti-idiotypic mechanisms involved in suppression of a mouse B cell lymphoma, BCL1. Journal of Immunology (Baltimore, Md. : 1950). 138: 628-34. PMID 3491853  0.263
1988 George AJ, Folkard SG, Hamblin TJ, Stevenson FK. Idiotypic vaccination as a treatment for a B cell lymphoma. Journal of Immunology (Baltimore, Md. : 1950). 141: 2168-74. PMID 3049800  0.263
1991 Stevenson FK, Bell AJ, Cusack R, Hamblin TJ, Slade CJ, Spellerberg MB, Stevenson GT. Preliminary studies for an immunotherapeutic approach to the treatment of human myeloma using chimeric anti-CD38 antibody. Blood. 77: 1071-9. PMID 1995092  0.262
2005 Di Genova G, Roddick J, McNicholl F, Stevenson FK. Vaccination of human subjects expands both specific and bystander memory T cells but antibody production remains vaccine specific. Blood. 107: 2806-13. PMID 16339400 DOI: 10.1182/blood-2005-08-3255  0.262
1996 Bhat NM, Bieber MM, Stevenson FK, Teng NNH. Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodies Clinical and Experimental Immunology. 105: 183-190. PMID 8697629  0.261
2000 Bhat NM, Bieber MM, Spellerberg MB, Stevenson FK, Teng NNH. Recognition of auto- and exoantigens by V4-34 gene encoded antibodies Scandinavian Journal of Immunology. 51: 134-140. PMID 10652159 DOI: 10.1046/j.1365-3083.2000.00654.x  0.261
1978 Stevenson FK, Elliott EV, Stevenson GT. Some effects on leukaemic B lymphocytes of antibodies to defined regions of their surface immunoglobulin. Immunology. 32: 549-57. PMID 415966  0.26
2000 Baxendale HE, Davis Z, White HN, Spellerberg MB, Stevenson FK, Goldblatt D. Immunogenetic analysis of the immune response to pneumococcal polysaccharide. European Journal of Immunology. 30: 1214-23. PMID 10760811 DOI: 10.1002/(SICI)1521-4141(200004)30:4<1214::AID-IMMU1214>3.0.CO;2-D  0.26
2002 Zhu D, Rice J, Savelyeva N, Stevenson FK. DNA fusion vaccines against B-cell tumors. Trends in Molecular Medicine. 7: 566-72. PMID 11733220 DOI: 10.1016/s1471-4914(01)02126-8  0.26
1989 Stevenson FK, Smith GJ, North J, Glennie MG, Hamblin TJ. Use of a cross reacting anti-idiotype to identify normal counterparts of neoplastic cells. Nouvelle Revue Francaise D'Hematologie. 30: 299-300. PMID 3265500  0.259
1984 Stevenson FK, Gregg EO, Smith JL, Stevenson GT. Secretion of immunoglobulin by neoplastic B lymphocytes from lymph nodes of patients with lymphoma. British Journal of Cancer. 50: 579-86. PMID 6333886 DOI: 10.1038/bjc.1984.224  0.259
2021 Valle-Argos B, Chiodin G, Bryant DJ, Taylor J, Lemm E, Duriez PJ, Rock PJ, Strefford JC, Forconi F, Burack RW, Packham G, Stevenson FK. DC-SIGN binding to mannosylated B-cell receptors in follicular lymphoma down-modulates receptor signaling capacity. Scientific Reports. 11: 11676. PMID 34083646 DOI: 10.1038/s41598-021-91112-7  0.259
1992 George AJ, Stevenson FK. Prospects for the treatment of B cell tumors using idiotypic vaccination. International Reviews of Immunology. 4: 271-310. PMID 2519930 DOI: 10.3109/08830188909044783  0.258
2001 Stevenson FK, Zhu D, Rice J. New strategies for vaccination and imunomodulation in NHL. Annals of Hematology. B132-4. PMID 11757697 DOI: 10.1007/pl00022778  0.258
2011 Stevenson FK, Mander A, Chudley L, Ottensmeier CH. DNA fusion vaccines enter the clinic. Cancer Immunology, Immunotherapy : Cii. 60: 1147-51. PMID 21644035 DOI: 10.1007/s00262-011-1042-2  0.258
2001 Forconi F, Sahota SS, Raspadori D, Mockridge CI, Lauria F, Stevenson FK. Tumor cells of hairy cell leukemia express multiple clonally related immunoglobulin isotypes via RNA splicing. Blood. 98: 1174-81. PMID 11493467 DOI: 10.1182/blood.v98.4.1174  0.258
2004 Stevenson FK, Rice J, Ottensmeier CH, Thirdborough SM, Zhu D. DNA fusion gene vaccines against cancer: from the laboratory to the clinic. Immunological Reviews. 199: 156-80. PMID 15233733 DOI: 10.1111/j.0105-2896.2004.00145.x  0.258
1999 Zhu D, Thompsett AR, Bedu-Addo G, Stevenson FK, Bates I. VH gene sequences from a novel tropical splenic lymphoma reveal a naive B cell as the cell of origin. British Journal of Haematology. 107: 114-20. PMID 10520031 DOI: 10.1046/j.1365-2141.1999.01679.x  0.257
2000 Garand R, Sahota SS, Avet-Loiseau H, Talmant P, Robillard N, Moreau A, Gaillard F, Stevenson FK, Bataille R. IgG-secreting lymphoplasmacytoid leukaemia: a B-cell disorder with extensively mutated VH genes undergoing Ig isotype-switching frequently associated with trisomy 12. British Journal of Haematology. 109: 71-80. PMID 10848784 DOI: 10.1046/j.1365-2141.2000.01971.x  0.257
1993 Bhat NM, Bieber MM, Chapman CJ, Stevenson FK, Teng NNH. Human antilipid A monoclonal antibodies bind to human B cells and the i antigen on cord red blood cells Journal of Immunology. 151: 5011-5021. PMID 7691963  0.257
1984 Gordon J, Abdul-Ahad AK, Hamblin TJ, Stevenson FK, Stevenson GT. Mechanisms of tumour cell escape encountered in treating lymphocytic leukaemia with anti-idiotypic antibody. British Journal of Cancer. 49: 547-57. PMID 6722005 DOI: 10.1038/bjc.1984.88  0.256
2004 Heslop HE, Stevenson FK, Molldrem JJ. Immunotherapy of hematologic malignancy. Hematology. American Society of Hematology. Education Program. 331-49. PMID 14633789 DOI: 10.1182/asheducation-2003.1.331  0.255
2004 Zhu D, Qi CF, Morse HC, Janz S, Stevenson FK. Deregulated expression of the Myc cellular oncogene drives development of mouse "Burkitt-like" lymphomas from naive B cells. Blood. 105: 2135-7. PMID 15522957 DOI: 10.1182/blood-2004-07-2573  0.255
2023 Stevenson FK, Forconi F. The essential microenvironmental role of oligomannoses inserted into the antigen-binding sites of lymphoma cells. Blood. PMID 37992212 DOI: 10.1182/blood.2023022703  0.255
1996 Sahota SS, Leo R, Hamblin TJ, Stevenson FK. Ig VH gene mutational patterns indicate different tumor cell status in human myeloma and monoclonal gammopathy of undetermined significance. Blood. 87: 746-55. PMID 8555499  0.253
2005 McCann K, Sahota SS, Stevenson FK, Ottensmeier CH. Idiotype gene rescue in follicular lymphoma. Methods in Molecular Medicine. 115: 145-71. PMID 15998967 DOI: 10.1385/1-59259-936-2:145  0.253
2002 Stevenson FK, Sahota SS, Ottensmeier CH, Zhu D, Forconi F, Hamblin TJ. The occurrence and significance of V gene mutations in B cell-derived human malignancy. Advances in Cancer Research. 83: 81-116. PMID 11665722 DOI: 10.1016/s0065-230x(01)83004-9  0.252
1978 Stevenson FK, Elliott EV. Mediation of cytotoxic functions by classes and subclasses of sheep antibody reactive with cell surface immunoglobulin idiotypic and constant region determinants. Immunology. 34: 353-8. PMID 75184  0.252
2014 Packham G, Krysov S, Allen A, Savelyeva N, Steele AJ, Forconi F, Stevenson FK. The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy. Haematologica. 99: 1138-48. PMID 24986876 DOI: 10.3324/haematol.2013.098384  0.252
2015 Linley A, Krysov S, Ponzoni M, Johnson PW, Packham G, Stevenson FK. Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells. Blood. 126: 1902-10. PMID 26194765 DOI: 10.1182/blood-2015-04-640805  0.251
2008 Chaise C, Buchan SL, Rice J, Marquet J, Rouard H, Kuentz M, Vittes GE, Molinier-Frenkel V, Farcet JP, Stauss HJ, Delfau-Larue MH, Stevenson FK. DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance. Blood. 112: 2956-64. PMID 18502835 DOI: 10.1182/blood-2008-02-137695  0.251
1982 Stevenson FK, Hamblin TJ, Stevenson GT. The nature of the immunoglobulin G on the surface of B lymphocytes in chronic lymphocytic leukemia. The Journal of Experimental Medicine. 154: 1965-9. PMID 6976409 DOI: 10.1084/jem.154.6.1965  0.25
2002 Rice J, Buchan S, Stevenson FK. Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen. Journal of Immunology (Baltimore, Md. : 1950). 169: 3908-13. PMID 12244189  0.249
2021 Stevenson FK, Forconi F, Kipps TJ. Exploring the pathways to chronic lymphocytic leukemia. Blood. 138: 827-835. PMID 34075408 DOI: 10.1182/blood.2020010029  0.249
1981 Stevenson FK, Morris D, Stevenson GT. Immunoglobulin produced by guinea-pig leukaemic B lymphocytes: its source and use as a monitor of tumour load. Immunology. 41: 313-21. PMID 6969218  0.248
1987 Wrightham M, Tutt AL, Glennie MJ, Hamblin TJ, Stevenson GT, Stevenson FK. Monoclonal anti-light chain idiotype as a tumor-specific probe for human neoplastic B lymphocytes. Blood. 69: 919-23. PMID 2434161  0.247
1991 George AJ, McBride HM, Glennie MJ, Smith LJ, Stevenson FK. Monoclonal antibodies raised against the idiotype of the murine B cell lymphoma, BCL1 act primarily with heavy chain determinants. Hybridoma. 10: 219-27. PMID 1908435 DOI: 10.1089/hyb.1991.10.219  0.247
2010 Krysov S, Potter KN, Mockridge CI, Coelho V, Wheatley I, Packham G, Stevenson FK. Surface IgM of CLL cells displays unusual glycans indicative of engagement of antigen in vivo. Blood. 115: 4198-205. PMID 20237321 DOI: 10.1182/blood-2009-12-254847  0.246
1996 Snow RE, Chapman CJ, Holgate ST, Stevenson FK. Immunogenetics of human IgE. Human Antibodies and Hybridomas. 7: 157-66. PMID 9140727  0.244
1996 Chapman CJ, Mockridge CI, Hamblin TJ, Stevenson FK. Tracking of the V4-34 (VH4-21) gene in human tonsil reveals clonal isotype switch events and a highly variable degree of somatic hypermutation. Clinical and Experimental Immunology. 105: 360-8. PMID 8706346 DOI: 10.1046/j.1365-2249.1996.d01-769.x  0.243
1996 Chapman CJ, Zhou JX, Gregory C, Rickinson AB, Stevenson FK. VH and VL gene analysis in sporadic Burkitt's lymphoma shows somatic hypermutation, intraclonal heterogeneity, and a role for antigen selection. Blood. 88: 3562-8. PMID 8896424  0.242
2017 Kipps TJ, Stevenson FK, Wu CJ, Croce CM, Packham G, Wierda WG, O'Brien S, Gribben J, Rai K. Chronic lymphocytic leukaemia. Nature Reviews. Disease Primers. 3: 16096. PMID 28102226 DOI: 10.1038/nrdp.2016.96  0.24
2000 Ottensmeier CH, Stevenson FK. Isotype switch variants reveal clonally related subpopulations in diffuse large B-cell lymphoma. Blood. 96: 2550-6. PMID 11001910  0.24
1996 Spellerberg MB, Chapman CJ, Mockridge CI, Isenberg DA, Stevenson FK. Dual recognition of lipid A and DNA by human antibodies encoded by the VH4-21 gene: a possible link between infection and lupus. Human Antibodies and Hybridomas. 6: 52-6. PMID 7492751  0.24
1995 Chapman CJ, Mockridge CI, Rowe M, Rickinson AB, Stevenson FK. Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity. Blood. 85: 2176-81. PMID 7718888  0.24
1983 Mufti GJ, Hamblin TJ, Stevenson FK, Fitchett M. Polycythaemia rubra vera and hairy cell leukaemia in the same patient: studies on the spleen. Journal of Clinical Pathology. 35: 1312-5. PMID 7174843 DOI: 10.1136/jcp.35.12.1312  0.24
2002 Zhu D, Orchard J, Oscier DG, Wright DH, Stevenson FK. V(H) gene analysis of splenic marginal zone lymphomas reveals diversity in mutational status and initiation of somatic mutation in vivo. Blood. 100: 2659-61. PMID 12239182 DOI: 10.1182/blood-2002-01-0169  0.239
1989 Dearman RJ, Stevenson FK, Wrightham M, Hamblin TJ, Glennie MJ, Stevenson GT. Lymphokine-activated killer cells from normal and lymphoma subjects are cytotoxic for cells coated with antibody derivatives displaying human Fc gamma. Blood. 72: 1985-91. PMID 2973819  0.239
2007 Zhu D, Williams JN, Rice J, Stevenson FK, Heckels JE, Christodoulides M. A DNA fusion vaccine induces bactericidal antibodies to a peptide epitope from the PorA porin of Neisseria meningitidis. Infection and Immunity. 76: 334-8. PMID 17967859 DOI: 10.1128/IAI.00943-07  0.238
1978 Elliott EV, Pindar A, Stevenson FK, Stevenson GT. Synergistic cytotoxic effects of antibodies directed against different cell surface determinants. Immunology. 34: 405-9. PMID 76604  0.238
1975 Stevenson GT, Stevenson FK. Antibody to a molecularly-defined antigen confined to a tumour cell surface. Nature. 254: 714-6. PMID 47617 DOI: 10.1038/254714a0  0.237
2005 Perkins SD, Flick-Smith HC, Garmory HS, Essex-Lopresti AE, Stevenson FK, Phillpotts RJ. Evaluation of the VP22 protein for enhancement of a DNA vaccine against anthrax. Genetic Vaccines and Therapy. 3: 3. PMID 15842732 DOI: 10.1186/1479-0556-3-3  0.237
2012 Zhu D, Spellerberg MB, King CA, Rice J, Thompsett AR, Stevenson FK. DNA fusion vaccines against B-cell tumors. Methods in Molecular Medicine. 29: 405-23. PMID 21374338 DOI: 10.1385/1-59259-688-6:405  0.237
2008 McCann KJ, Ottensmeier CH, Callard A, Radcliffe CM, Harvey DJ, Dwek RA, Rudd PM, Sutton BJ, Hobby P, Stevenson FK. Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma. Molecular Immunology. 45: 1567-72. PMID 18022232 DOI: 10.1016/J.Molimm.2007.10.009  0.236
2011 Savelyeva N, Shipton M, Suchacki A, Babbage G, Stevenson FK. High-affinity memory B cells induced by conjugate vaccines against weak tumor antigens are vulnerable to nonconjugated antigen. Blood. 118: 650-9. PMID 21613251 DOI: 10.1182/blood-2011-01-328864  0.235
2017 Ghia P, Nadel B, Sander B, Stamatopoulos K, Stevenson FK. Early stages in the ontogeny of small B-cell lymphomas: genetics and microenvironment. Journal of Internal Medicine. 282: 395-414. PMID 28393412 DOI: 10.1111/joim.12608  0.235
2001 Potter KN, Thomson RK, Hamblin A, Richards SD, Lindsay JG, Stevenson FK. Immunogenetic analysis reveals that epitope shifting occurs during B-cell affinity maturation in primary biliary cirrhosis Journal of Molecular Biology. 306: 37-46. PMID 11178892 DOI: 10.1006/jmbi.2000.4210  0.234
2010 Zuckerman NS, McCann KJ, Ottensmeier CH, Barak M, Shahaf G, Edelman H, Dunn-Walters D, Abraham RS, Stevenson FK, Mehr R. Ig gene diversification and selection in follicular lymphoma, diffuse large B cell lymphoma and primary central nervous system lymphoma revealed by lineage tree and mutation analyses. International Immunology. 22: 875-87. PMID 21059768 DOI: 10.1093/intimm/dxq441  0.234
2010 Stevenson FK, Ottensmeier CH, Rice J. DNA vaccines against cancer come of age. Current Opinion in Immunology. 22: 264-70. PMID 20172703 DOI: 10.1016/j.coi.2010.01.019  0.233
2016 Chotprakaikiat W, Allen A, Bui-Minh D, Harden E, Jobsri J, Cavallo F, Gleba Y, Stevenson FK, Ottensmeier C, Klimyuk V, Savelyeva N. A plant-expressed conjugate vaccine breaks CD4(+) tolerance and induces potent immunity against metastatic Her2(+) breast cancer. Oncoimmunology. 5: e1166323. PMID 27471642 DOI: 10.1080/2162402X.2016.1166323  0.233
2020 Chiorazzi N, Stevenson FK. Celebrating 20 Years of IGHV Mutation Analysis in CLL. Hemasphere. 4: e334. PMID 32382709 DOI: 10.1097/HS9.0000000000000334  0.233
1994 Stevenson FK, Longhurst C, Chapman CJ, Ehrenstein M, Spellerberg MB, Hamblin TJ, Ravirajan CT, Latchman D, Isenberg D. Utilization of the VH4-21 gene segment by anti-DNA antibodies from patients with systemic lupus erythematosus. Journal of Autoimmunity. 6: 809-25. PMID 8155258 DOI: 10.1006/JAUT.1993.1066  0.233
2014 Krysov S, Steele AJ, Coelho V, Linley A, Sanchez Hidalgo M, Carter M, Potter KN, Kennedy B, Duncombe AS, Ashton-Key M, Forconi F, Stevenson FK, Packham G. Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK. Blood. 124: 3101-9. PMID 25170122 DOI: 10.1182/blood-2014-04-567198  0.233
2015 Jobsri J, Allen A, Rajagopal D, Shipton M, Kanyuka K, Lomonossoff GP, Ottensmeier C, Diebold SS, Stevenson FK, Savelyeva N. Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody. Plos One. 10: e0118096. PMID 25692288 DOI: 10.1371/journal.pone.0118096  0.232
2004 Mockridge CI, Rahman A, Buchan S, Hamblin T, Isenberg DA, Stevenson FK, Potter KN. Common patterns of B cell perturbation and expanded V4-34 immunoglobulin gene usage in autoimmunity and infection. Autoimmunity. 37: 9-15. PMID 15115306 DOI: 10.1080/08916930310001624656  0.232
1984 Tutt AL, Stevenson FK, Smith JL, Stevenson GT. Antibodies against urinary light chain idiotypes as agents for detection and destruction of human neoplastic B lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 131: 3058-63. PMID 6417240  0.232
2011 Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G. B-cell receptor signaling in chronic lymphocytic leukemia. Blood. 118: 4313-20. PMID 21816833 DOI: 10.1182/blood-2011-06-338855  0.232
1998 Mockridge CI, Chapman CJ, Spellerberg MB, Sheth B, Fleming TP, Isenberg DA, Stevenson FK. Sequence analysis of V(4-34)-encoded antibodies from single B cells of two patients with systemic lupus erythematosus (SLE). Clinical and Experimental Immunology. 114: 129-36. PMID 9764614 DOI: 10.1046/j.1365-2249.1998.00703.x  0.231
2006 Babbage G, Ottensmeier CH, Blaydes J, Stevenson FK, Sahota SS. Immunoglobulin heavy chain locus events and expression of activation-induced cytidine deaminase in epithelial breast cancer cell lines. Cancer Research. 66: 3996-4000. PMID 16618718 DOI: 10.1158/0008-5472.CAN-05-3704  0.23
1998 Ottensmeier CH, Thompsett AR, Zhu D, Wilkins BS, Sweetenham JW, Stevenson FK. Analysis of VH genes in follicular and diffuse lymphoma shows ongoing somatic mutation and multiple isotype transcripts in early disease with changes during disease progression. Blood. 91: 4292-9. PMID 9596678  0.23
2003 Sahota SS, Forconi F, Ottensmeier CH, Stevenson FK. Origins of the malignant clone in typical Waldenstrom's macroglobulinemia. Seminars in Oncology. 30: 136-41. PMID 12720123 DOI: 10.1053/sonc.2003.50072  0.229
2022 Taylor J, Wilmore S, Marriot S, Rogers-Broadway KR, Fell R, Minton AR, Branch T, Ashton-Key M, Coldwell M, Stevenson FK, Forconi F, Steele AJ, Packham G, Yeomans A. B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells. Cellular Signalling. 94: 110311. PMID 35306137 DOI: 10.1016/j.cellsig.2022.110311  0.229
2006 Rice J, Dunn S, Piper K, Buchan SL, Moss PA, Stevenson FK. DNA fusion vaccines induce epitope-specific cytotoxic CD8(+) T cells against human leukemia-associated minor histocompatibility antigens. Cancer Research. 66: 5436-42. PMID 16707472 DOI: 10.1158/0008-5472.CAN-05-3130  0.229
2012 Forconi F, Potter KN, Sozzi E, Henderson I, Cencini E, Rossi D, Bomben R, Gattei V, Gaidano G, Packham G, Stevenson FK. The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells. Blood. 119: 2106-9. PMID 22234701 DOI: 10.1182/blood-2011-08-375501  0.229
2006 Stevenson FK, Rice J. Optimizing cancer immunotherapy trials: back to basics. European Journal of Immunology. 36: 1070-3. PMID 16639707 DOI: 10.1002/eji.200636085  0.228
1981 Hamblin TJ, Abdul-Ahad AK, Gordon J, Stevenson FK, Stevenson GT. Preliminary experience in treating lymphocytic leukaemia with antibody to immunoglobulin idiotypes on the cell surfaces. British Journal of Cancer. 42: 495-502. PMID 7192154 DOI: 10.1038/bjc.1980.271  0.228
1997 Thorpe SJ, Boult CE, Stevenson FK, Scott ML, Sutherland J, Spellerberg MB, Natvig JB, Thompson KM. Cold agglutinin activity is common among human monoclonal IgM Rh system antibodies using the V4-34 heavy chain variable gene segment. Transfusion. 37: 1111-6. PMID 9426632  0.228
1987 Gregg EO, Bridges SH, Youle RJ, Longo DL, Houston LL, Glennie MJ, Stevenson FK, Green I. Whole ricin and recombinant ricin A chain idiotype-specific immunotoxins for therapy of the guinea pig L2C B cell leukemia. Journal of Immunology (Baltimore, Md. : 1950). 138: 4502-8. PMID 3495593  0.228
1986 Stevenson GT, Glennie MJ, Paul FE, Stevenson FK, Watts HF, Wyeth P. Preparation and properties of FabIgG, a chimeric univalent antibody designed to attack tumour cells. Bioscience Reports. 5: 991-8. PMID 3879458 DOI: 10.1007/BF01119911  0.227
1996 Mockridge CI, Chapman CJ, Spellerberg MB, Isenberg DA, Stevenson FK. Use of phage surface expression to analyze regions of human V4-34(VH4-21)-encoded IgG autoantibody required for recognition of DNA: no involvement of the 9G4 idiotope. Journal of Immunology (Baltimore, Md. : 1950). 157: 2449-54. PMID 8805644  0.226
1999 Sahota SS, Garand R, Mahroof R, Smith A, Juge-Morineau N, Stevenson FK, Bataille R. V(H) gene analysis of IgM-secreting myeloma indicates an origin from a memory cell undergoing isotype switch events. Blood. 94: 1070-6. PMID 10419900  0.226
1988 Stevenson FK, George AJ, Tutt AL, Glennie MJ, Stevenson GT. Involvement of innate and induced anti-idiotypic mechanisms in suppression of B cell tumors. Monographs in Allergy. 22: 184-93. PMID 3501833  0.226
2002 Zhu D, McCarthy H, Ottensmeier CH, Johnson P, Hamblin TJ, Stevenson FK. Acquisition of potential N-glycosylation sites in the immunoglobulin variable region by somatic mutation is a distinctive feature of follicular lymphoma. Blood. 99: 2562-8. PMID 11895794 DOI: 10.1182/blood.v99.7.2562  0.226
2004 Forconi F, Sahota SS, Raspadori D, Ippoliti M, Babbage G, Lauria F, Stevenson FK. Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch. Blood. 104: 3312-7. PMID 15284115 DOI: 10.1182/blood-2004-03-0950  0.226
1991 Dyke RJ, McBride H, George AJT, Hamblin TJ, Stevenson FK. Idiotypic vaccination against B-cell lymphoma leads to dormant tumour Cellular Immunology. 132: 70-83. PMID 2065360 DOI: 10.1016/0008-8749(91)90007-X  0.225
1999 Stevenson FK, Link CJ, Traynor A, Yu H, Corr M. DNA vaccination against multiple myeloma. Seminars in Hematology. 36: 38-42. PMID 9989489  0.225
1999 Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 94: 1848-54. PMID 10477713  0.224
2012 Paterson A, Mockridge CI, Adams JE, Krysov S, Potter KN, Duncombe AS, Cook SJ, Stevenson FK, Packham G. Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia. Blood. 119: 1726-36. PMID 22160382 DOI: 10.1182/blood-2011-07-367417  0.224
2005 Sahota SS, Babbage G, Zojer N, Ottensmeier CH, Stevenson FK. Determining mutational status of immunoglobulin v genes in chronic lymphocytic leukemia: a useful prognostic indicator. Methods in Molecular Medicine. 115: 129-44. PMID 15998966 DOI: 10.1385/1-59259-936-2:129  0.223
1998 Thorpe SJ, Turner CE, Stevenson FK, Spellerberg MB, Thorpe R, Natvig JB, Thompson KM. Human monoclonal antibodies encoded by the V4-34 gene segment show cold agglutinin activity and variable multireactivity which correlates with the predicted charge of the heavy-chain variable region. Immunology. 93: 129-36. PMID 9536129 DOI: 10.1046/j.1365-2567.1998.00406.x  0.223
2006 Potter KN, Mockridge CI, Neville L, Wheatley I, Schenk M, Orchard J, Duncombe AS, Packham G, Stevenson FK. Structural and functional features of the B-cell receptor in IgG-positive chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1672-9. PMID 16551848 DOI: 10.1158/1078-0432.CCR-05-2164  0.223
1987 Hamblin TJ, Cattan AR, Glennie MJ, MacKenzie MR, Stevenson FK, Watts HF, Stevenson GT. Initial experience in treating human lymphoma with a chimeric univalent derivative of monoclonal anti-idiotype antibody. Blood. 69: 790-7. PMID 3101763  0.223
1994 Moazzeni M, Mosayyebi G, Stevenson FK, Abbot S, Mageed RA, Shokri F. Biased utilization of immunoglobulin variable region heavy- and light-chain genes by the malignant CD5- B lymphocytes from patients with Burkitt's lymphoma. International Journal of Cancer. 58: 226-32. PMID 7517918 DOI: 10.1002/ijc.2910580214  0.222
2003 Cochran DA, Evans CA, Blinco D, Burthem J, Stevenson FK, Gaskell SJ, Whetton AD. Proteomic analysis of chronic lymphocytic leukemia subtypes with mutated or unmutated Ig V(H) genes. Molecular & Cellular Proteomics : McP. 2: 1331-41. PMID 14557598 DOI: 10.1074/Mcp.M300055-Mcp200  0.221
2021 Wilmore S, Rogers-Broadway KR, Taylor J, Lemm E, Fell R, Stevenson FK, Forconi F, Steele AJ, Coldwell M, Packham G, Yeomans A. Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells. Cellular and Molecular Life Sciences : Cmls. PMID 34398253 DOI: 10.1007/s00018-021-03910-x  0.221
2018 Drennan S, Chiodin G, D'Avola A, Tracy I, Johnson PW, Trentin L, Steele AJ, Packham G, Stevenson FK, Forconi F. Ibrutinib therapy releases leukemic surface IgM from antigen drive in chronic lymphocytic leukemia patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30373751 DOI: 10.1158/1078-0432.CCR-18-1286  0.219
2002 Rice J, de Lima B, Stevenson FK, Stevenson PG. A gamma-herpesvirus immune evasion gene allows tumor cells in vivo to escape attack by cytotoxic T cells specific for a tumor epitope. European Journal of Immunology. 32: 3481-7. PMID 12442330 DOI: 10.1002/1521-4141(200212)32:12<3481::AID-IMMU3481>3.0.CO;2-J  0.219
2013 Coelho V, Krysov S, Steele A, Sanchez Hidalgo M, Johnson PW, Chana PS, Packham G, Stevenson FK, Forconi F. Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function. Blood. 122: 2664-72. PMID 23954894 DOI: 10.1182/blood-2013-02-485425  0.218
2015 Yeomans A, Thirdborough SM, Valle-Argos B, Linley A, Krysov S, Sanchez Hidalgo M, Leonard E, Ishfaq M, Wagner SD, Willis AE, Steele AJ, Stevenson FK, Forconi F, Coldwell MJ, Packham G. Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation. Blood. PMID 26491071 DOI: 10.1182/blood-2015-07-660969  0.218
1996 Longhurst C, Ehrenstein MR, Leaker B, Stevenson FK, Spellerberg M, Chapman C, Latchmen D, Isenberg DA, Cambridge G. Analysis of immunoglobulin variable region genes of a human IgM anti-myeloperoxidase antibody derived from a patient with vasculitis. Immunology. 87: 334-8. PMID 8698399 DOI: 10.1046/j.1365-2567.1996.463529.x  0.218
2010 Chapman CJ, Dunn-Walters DK, Stevenson FK, Hussell T, Isaacson PG, Spencer J. Sequence analysis of immunoglobulin variable region genes that encode autoantibodies expressed by lymphomas of mucosa associated lymphoid tissue. Clinical Molecular Pathology. 49: M29-32. PMID 16696041 DOI: 10.1136/mp.49.1.m29  0.218
1997 Chapman CJ, Mockridge CI, Spellerberg MB, Zhu D, Stevenson FK. Phage surface expression for analysis of recognition sites of human autoantibodies: comparison of single chain Fv and Fab. Human Antibodies. 8: 124-8. PMID 9322082  0.217
1996 Li Y, Spellerberg MB, Stevenson FK, Capra JD, Potter KN. The I binding specificity of human VH 4-34 (VH 4-21) encoded antibodies is determined by both VH framework region 1 and complementarity determining region 3. Journal of Molecular Biology. 256: 577-89. PMID 8604140  0.213
1990 Jefferies LC, Stevenson FK, Goldman J, Bennett IM, Spitalnik SL, Silberstein LE. Anti-idiotypic antibodies specific for a pathologic anti-Pr2 cold agglutinin. Transfusion. 30: 495-502. PMID 2116048 DOI: 10.1046/j.1537-2995.1990.30690333478.x  0.213
2004 Rice J, Buchan S, Dewchand H, Simpson E, Stevenson FK. DNA fusion vaccines induce targeted epitope-specific CTLs against minor histocompatibility antigens from a normal or tolerized repertoire. Journal of Immunology (Baltimore, Md. : 1950). 173: 4492-9. PMID 15383580  0.212
1992 Ling NR, Stevenson FK, Brown B. Urinary excretion of CD23 antigen in normal individuals and patients with chronic lymphocytic leukaemia (CLL). Clinical and Experimental Immunology. 86: 360-6. PMID 1721010 DOI: 10.1111/j.1365-2249.1991.tb02938.x  0.211
2010 Di Genova G, Savelyeva N, Suchacki A, Thirdborough SM, Stevenson FK. Bystander stimulation of activated CD4+ T cells of unrelated specificity following a booster vaccination with tetanus toxoid. European Journal of Immunology. 40: 976-85. PMID 20104490 DOI: 10.1002/eji.200940017  0.21
2002 Potter KN, Mockridge CI, Rahman A, Buchan S, Hamblin T, Davidson B, Isenberg DA, Stevenson FK. Disturbances in peripheral blood B cell subpopulations in autoimmune patients. Lupus. 11: 872-7. PMID 12529053 DOI: 10.1191/0961203302lu309oa  0.21
1995 Stevenson FK, Zhu D, King CA, Ashworth LJ, Kumar S, Hawkins RE. Idiotypic DNA vaccines against B-cell lymphoma Immunological Reviews. 210-228. PMID 7590827  0.209
2002 Sahota SS, Forconi F, Ottensmeier CH, Provan D, Oscier DG, Hamblin TJ, Stevenson FK. Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events. Blood. 100: 1505-7. PMID 12149241  0.209
2005 Buchan S, Grønevik E, Mathiesen I, King CA, Stevenson FK, Rice J. Electroporation as a "prime/boost" strategy for naked DNA vaccination against a tumor antigen. Journal of Immunology (Baltimore, Md. : 1950). 174: 6292-8. PMID 15879128  0.208
1992 Stevenson FK. Update on tumor vaccines. International Journal of Clinical & Laboratory Research. 22: 84-9. PMID 1504310 DOI: 10.1007/BF02591402  0.207
1994 Zhu D, Hawkins RE, Hamblin TJ, Stevenson FK. Clonal history of a human follicular lymphoma as revealed in the immunoglobulin variable region genes British Journal of Haematology. 86: 505-512. PMID 8043433  0.206
1999 Rice J, King CA, Spellerberg MB, Fairweather N, Stevenson FK. Manipulation of pathogen-derived genes to influence antigen presentation via DNA vaccines. Vaccine. 17: 3030-8. PMID 10462238 DOI: 10.1016/s0264-410x(99)00171-1  0.206
2004 Forconi F, Sahota SS, Lauria F, Stevenson FK. Revisiting the definition of somatic mutational status in B-cell tumors: does 98% homology mean that a V(H)-gene is unmutated? Leukemia. 18: 882-3. PMID 14973503 DOI: 10.1038/sj.leu.2403312  0.206
2002 Zhu D, Stevenson FK. DNA gene fusion vaccines against cancer. Current Opinion in Molecular Therapeutics. 4: 41-8. PMID 11883694  0.204
1998 Janezic A, Chapman CJ, Snow RE, Hourihane JO, Warner JO, Stevenson FK. Immunogenetic analysis of the heavy chain variable regions of IgE from patients allergic to peanuts. The Journal of Allergy and Clinical Immunology. 101: 391-6. PMID 9525457 DOI: 10.1016/S0091-6749(98)70253-2  0.204
2007 Mockridge CI, Potter KN, Wheatley I, Neville LA, Packham G, Stevenson FK. Reversible anergy of sIgM-mediated signaling in the two subsets of CLL defined by VH-gene mutational status. Blood. 109: 4424-31. PMID 17255355 DOI: 10.1182/blood-2006-11-056648  0.203
1976 Stevenson FK, Mole LE, Raymont CM, Stevenson GT. A gamma Bence-Jones protein in guinea pigs. The Biochemical Journal. 151: 751-3. PMID 814896 DOI: 10.1042/bj1510751  0.2
2009 McCann KJ, Ashton-Key M, Smith K, Stevenson FK, Ottensmeier CH. Primary central nervous system lymphoma: tumor-related clones exist in the blood and bone marrow with evidence for separate development. Blood. 113: 4677-80. PMID 19096008 DOI: 10.1182/blood-2008-09-179366  0.199
2010 Forconi F, Potter KN, Wheatley I, Darzentas N, Sozzi E, Stamatopoulos K, Mockridge CI, Packham G, Stevenson FK. The normal IGHV1-69-derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL. Blood. 115: 71-7. PMID 19887677 DOI: 10.1182/blood-2009-06-225813  0.199
2003 Zhu D, Ottensmeier CH, Du MQ, McCarthy H, Stevenson FK. Incidence of potential glycosylation sites in immunoglobulin variable regions distinguishes between subsets of Burkitt's lymphoma and mucosa-associated lymphoid tissue lymphoma. British Journal of Haematology. 120: 217-22. PMID 12542478 DOI: 10.1046/j.1365-2141.2003.04064.x  0.199
1991 Stevenson FK. Tumor vaccines. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 5: 2250-7. PMID 1860616 DOI: 10.1096/fasebj.5.9.1860616  0.199
1995 Chapman CJ, Spellerberg MB, Hamblin TJ, Stevenson FK. Pattern of usage of the VH4-21 gene by B lymphocytes in a patient with EBV infection indicates ongoing mutation and class switching. Molecular Immunology. 32: 347-53. PMID 7739572 DOI: 10.1016/0161-5890(94)00162-t  0.199
1992 Pascual V, Victor K, Spellerberg M, Hamblin TJ, Stevenson FK, Capra JD. VH restriction among human cold agglutinins: The VH4-21 gene segment is required to encode anti-I and anti-I specificities Journal of Immunology. 149: 2337-2344. PMID 1382098  0.198
1995 Snow RE, Chapman CJ, Frew AJ, Holgate ST, Stevenson FK. Analysis of Ig VH region genes encoding IgE antibodies in splenic B lymphocytes of a patient with asthma. Journal of Immunology (Baltimore, Md. : 1950). 154: 5576-81. PMID 7730656  0.198
2003 Babbage G, Garand R, Robillard N, Zojer N, Stevenson FK, Sahota SS. Mantle cell lymphoma with t(11;14) and unmutated or mutated VH genes expresses AID and undergoes isotype switch events. Blood. 103: 2795-8. PMID 14551145 DOI: 10.1182/blood-2003-05-1632  0.198
1991 Thompson KM, Sutherland J, Barden G, Melamed MD, Randen I, Natvig JB, Pascual V, Capra JD, Stevenson FK. Human monoclonal antibodies against blood group antigens preferentially express a VH4-21 variable region gene-associated epitope. Scandinavian Journal of Immunology. 34: 509-18. PMID 1718028  0.198
1986 Stevenson FK, George AJ, Walters MT, Hamblin TJ. Analysis of soluble HLA class II antigenic material in patients with immunological diseases using monoclonal antibodies. Journal of Immunological Methods. 86: 187-90. PMID 2418122 DOI: 10.1016/0022-1759(86)90451-5  0.197
2001 Stevenson FK, Rosenberg W. DNA vaccination: a potential weapon against infection and cancer. Vox Sanguinis. 80: 12-8. PMID 11339062 DOI: 10.1046/j.1423-0410.2001.00009.x  0.197
1990 Stevenson FK, Douglass WA, Spellerberg MB, Walters MT, Cawley MI. Soluble histocompatibility antigens in synovial fluids of patients with rheumatoid arthritis. Clinical and Experimental Immunology. 80: 32-7. PMID 2323100 DOI: 10.1111/j.1365-2249.1990.tb06437.x  0.196
2013 Campos-Perez J, Rice J, Escors D, Collins M, Paterson A, Savelyeva N, Stevenson FK. DNA fusion vaccine designs to induce tumor-lytic CD8+ T-cell attack via the immunodominant cysteine-containing epitope of NY-ESO 1. International Journal of Cancer. 133: 1400-7. PMID 23494538 DOI: 10.1002/ijc.28156  0.196
1998 Chapman CJ, Wright D, Stevenson FK. Insight into Burkitt's lymphoma from immunoglobulin variable region gene analysis. Leukemia & Lymphoma. 30: 257-67. PMID 9713958 DOI: 10.3109/10428199809057539  0.194
2007 Radcliffe JN, Roddick JS, Friedmann PS, Stevenson FK, Thirdborough SM. Prime-boost with alternating DNA vaccines designed to engage different antigen presentation pathways generates high frequencies of peptide-specific CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 177: 6626-33. PMID 17082574 DOI: 10.4049/jimmunol.177.10.6626  0.193
2015 McCann KJ, Godeseth R, Chudley L, Mander A, Di Genova G, Lloyd-Evans P, Kerr JP, Malykh VB, Jenner MW, Orchard KH, Stevenson FK, Ottensmeier CH. Idiotypic DNA vaccination for the treatment of multiple myeloma: safety and immunogenicity in a phase I clinical study. Cancer Immunology, Immunotherapy : Cii. 64: 1021-32. PMID 25982371 DOI: 10.1007/s00262-015-1703-7  0.191
1991 George AJ, Foreman RC, Stevenson FK. Characterisation of a light chain loss variant of the BCL1 lymphoma. Molecular Immunology. 28: 789-99. PMID 1649967 DOI: 10.1016/0161-5890(91)90122-z  0.191
1999 Thompsett AR, Ellison DW, Stevenson FK, Zhu D. V(H) gene sequences from primary central nervous system lymphomas indicate derivation from highly mutated germinal center B cells with ongoing mutational activity. Blood. 94: 1738-46. PMID 10477699  0.191
1983 Stevenson FK, Stevenson GT, Tutt AL. The export of immunoglobulin D by human neoplastic B lymphocytes. The Journal of Experimental Medicine. 157: 337-41. PMID 6401318 DOI: 10.1084/jem.157.1.337  0.19
1985 Mufti GJ, Hamblin TJ, Stevenson FK, Fitchett M. Polycythemia rubra vera and hairy cell leukemia. Acta Haematologica. 73: 189. PMID 3929540 DOI: 10.1159/000206322  0.19
2004 Forconi F, Capello D, Berra E, Rossi D, Gloghini A, Cerri M, Muti G, Morra E, Paulli M, Magrini U, Lucioni M, Rambaldi A, Lauria F, Carbone A, Stevenson FK, et al. Incidence of novel N-glycosylation sites in the B-cell receptor of lymphomas associated with immunodeficiency British Journal of Haematology. 124: 604-609. PMID 14871246 DOI: 10.1111/j.1365-2141.2004.04816.x  0.189
1998 Thomson RK, Davis Z, Palmer JM, Arthur MJ, Yeaman SJ, Chapman CJ, Spellerberg MB, Stevenson FK. Immunogenetic analysis of a panel of monoclonal IgG and IgM anti-PDC-E2/X antibodies derived from patients with primary biliary cirrhosis. Journal of Hepatology. 28: 582-94. PMID 9566826 DOI: 10.1016/S0168-8278(98)80281-X  0.189
2019 Lemm EA, Valle-Argos B, Smith LD, Richter J, Gebreselassie Y, Carter MJ, Karolova J, Svaton M, Helman K, Weston-Bell NJ, Karydis L, Williamson CT, Lenz G, Pettigrew J, Harwig C, ... Stevenson FK, et al. Preclinical evaluation of a novel SHIP1 phosphatase activator for inhibition of PI3K signaling in malignant B-cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31831562 DOI: 10.1158/1078-0432.CCR-19-2202  0.188
2016 Aguilar-Hernandez MM, Blunt MD, Dobson R, Yeomans A, Thirdborough S, Larrayoz M, Smith LD, Linley A, Strefford JC, Davies A, Johnson PM, Savelyeva N, Cragg M, Forconi F, Packham G, ... Stevenson FK, et al. IL-4 enhances expression and function of surface IgM in CLL cells. Blood. PMID 27002119 DOI: 10.1182/blood-2015-11-682906  0.188
2009 Chen CG, Lu YT, Lin M, Savelyeva N, Stevenson FK, Zhu D. Amplification of immune responses against a DNA-delivered idiotypic lymphoma antigen by fusion to the B subunit of E. coli heat labile toxin. Vaccine. 27: 4289-96. PMID 19450635 DOI: 10.1016/j.vaccine.2009.05.025  0.186
2000 Sahota SS, Davis Z, Hamblin TJ, Stevenson FK. Somatic mutation of bcl-6 genes can occur in the absence of V(H) mutations in chronic lymphocytic leukemia. Blood. 95: 3534-40. PMID 10828040  0.184
2008 Radcliffe JN, Roddick JS, Stevenson FK, Thirdborough SM. Prolonged antigen expression following DNA vaccination impairs effector CD8+ T cell function and memory development. Journal of Immunology (Baltimore, Md. : 1950). 179: 8313-21. PMID 18056376 DOI: 10.4049/jimmunol.179.12.8313  0.184
1999 Stevenson FK, Natvig J. Autoantibodies revealed: the role of B cells in autoimmune disease. Immunology Today. 20: 296-8. PMID 10475678 DOI: 10.1016/s0167-5699(98)01421-2  0.183
1999 Snow RE, Djukanovic R, Stevenson FK. Analysis of immunoglobulin E VH transcripts in a bronchial biopsy of an asthmatic patient confirms bias towards VH5, and indicates local clonal expansion, somatic mutation and isotype switch events. Immunology. 98: 646-51. PMID 10594700  0.183
2011 Vittes GE, Harden EL, Ottensmeier CH, Rice J, Stevenson FK. DNA fusion gene vaccines induce cytotoxic T-cell attack on naturally processed peptides of human prostate-specific membrane antigen. European Journal of Immunology. 41: 2447-56. PMID 21604260 DOI: 10.1002/eji.201141518  0.182
1981 Gordon J, Hamblin TJ, Smith JL, Stevenson FK, Stevenson GT. A human b-cell lymphoma synthesizing and expressing surface mu-chain in the absence of detectable light chain. Blood. 58: 552-6. PMID 6789844  0.181
1998 Zhu D, van Arkel C, King CA, Meirvenne SV, de Greef C, Thielemans K, Radl J, Stevenson FK. Immunoglobulin VH gene sequence analysis of spontaneous murine immunoglobulin-secreting B-cell tumours with clinical features of human disease. Immunology. 93: 162-70. PMID 9616364 DOI: 10.1046/j.1365-2567.1998.00428.x  0.181
2005 Packham G, Stevenson FK. Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia. Immunology. 114: 441-9. PMID 15804279 DOI: 10.1111/j.1365-2567.2005.02117.x  0.178
2005 Perkins SD, Hartley MG, Lukaszewski RA, Phillpotts RJ, Stevenson FK, Bennett AM. VP22 enhances antibody responses from DNA vaccines but not by intercellular spread. Vaccine. 23: 1931-40. PMID 15734065 DOI: 10.1016/j.vaccine.2004.10.033  0.177
2016 Yeomans A, Lemm E, Wilmore S, Cavell BE, Valle-Argos B, Krysov S, Sanchez Hidalgo M, Leonard E, Willis AE, Forconi F, Stevenson FK, Steele AJ, Coldwell MJ, Packham G. PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells. Oncotarget. PMID 27579538 DOI: 10.18632/oncotarget.11655  0.176
2003 Zojer N, Ludwig H, Fiegl M, Stevenson FK, Sahota SS. Patterns of somatic mutations in VH genes reveal pathways of clonal transformation from MGUS to multiple myeloma. Blood. 101: 4137-9. PMID 12531815 DOI: 10.1182/blood-2002-09-2825  0.175
2006 Stevenson FK. Update on cancer vaccines. Current Opinion in Oncology. 17: 573-7. PMID 16224235 DOI: 10.1097/01.cco.0000181406.60213.c7  0.175
1998 Chapman CJ, Wright D, Feizi HP, Davis Z, Stevenson FK. V(H) gene analysis of Burkitt's lymphoma in children from north-western Iran. British Journal of Haematology. 103: 1116-23. PMID 9886329  0.175
1997 Oscier DG, Thompsett A, Zhu D, Stevenson FK. Differential rates of somatic hypermutation in V(H) genes among subsets of chronic lymphocytic leukemia defined by chromosomal abnormalities. Blood. 89: 4153-60. PMID 9166858  0.174
2001 Rice J, Elliott T, Buchan S, Stevenson FK. DNA fusion vaccine designed to induce cytotoxic T cell responses against defined peptide motifs: implications for cancer vaccines. Journal of Immunology (Baltimore, Md. : 1950). 167: 1558-65. PMID 11466377  0.173
1987 Walters MT, Stevenson FK, Herbert A, Cawley MI, Smith JL. Lymphoma in Sjögren's syndrome: urinary monoclonal free light chains as a diagnostic aid and a means of tumour monitoring. Scandinavian Journal of Rheumatology. Supplement. 61: 114-7. PMID 3109020  0.172
1983 Stevenson GT, Stevenson FK. Treatment of lymphoid tumors with anti-idiotype antibodies. Springer Seminars in Immunopathology. 6: 99-115. PMID 6351310 DOI: 10.1007/BF01857369  0.171
1995 Chapman CJ, Mockridge CI, Spellerberg MB, Isenberg DA, Hamblin TJ, Stevenson FK. Use of a phage expression system to produce Fabs from human autoanti-DNA antibodies encoded by the VH4-21 gene segment. Annals of the New York Academy of Sciences. 764: 576-9. PMID 7486589 DOI: 10.1111/j.1749-6632.1995.tb55886.x  0.17
2012 Krysov S, Dias S, Paterson A, Mockridge CI, Potter KN, Smith KA, Ashton-Key M, Stevenson FK, Packham G. Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells. Blood. 119: 170-9. PMID 22086413 DOI: 10.1182/blood-2011-07-370403  0.17
2006 Coenen S, Pickering B, Potter KN, Johnson PW, Stevenson FK, Packham G. The relevance of sequence insertions in the Mcl-1 promoter in chronic lymphocytic leukemia and in normal cells. Haematologica. 90: 1285-6. PMID 16154859  0.166
2007 Babbage G, Townsend M, Zojer N, Mockridge IC, Garand R, Barlogie B, Shaughnessy J, Stevenson FK, Sahota SS. IgM-expressing Waldenstrom's macroglobulinemia tumor cells reveal a potential for isotype switch events in vivo. Leukemia. 21: 827-30. PMID 17287856 DOI: 10.1038/sj.leu.2404538  0.165
2022 Chiodin G, Drennan S, Martino EA, Ondrisova L, Henderson I, Del Rio L, Tracy I, D'Avola A, Parker H, Bonfiglio S, Scarfò L, Sutton LA, Strefford JC, Forster J, Brake O, ... ... Stevenson FK, et al. High surface IgM levels associate with shorter response to ibrutinib and BTK bypass in CLL patients. Blood Advances. PMID 35640238 DOI: 10.1182/bloodadvances.2021006659  0.165
2006 Sahota SS, Goonewardena CM, Cooper CD, Liggins AP, Ait-Tahar K, Zojer N, Stevenson FK, Banham AH, Pulford K. PASD1 is a potential multiple myeloma-associated antigen. Blood. 108: 3953-5. PMID 17114574 DOI: 10.1182/blood-2006-04-014621  0.164
1983 Stevenson FK, Spellerberg M, Smith JL. Monoclonal immunoglobulin light chain in urine of patients with B lymphocytic disease: its source and use as a diagnostic aid. British Journal of Cancer. 47: 607-12. PMID 6405775 DOI: 10.1038/bjc.1983.98  0.163
2006 Sahota SS, Stevenson FK. Lineage complexity in multiple myeloma? Leukemia & Lymphoma. 47: 1997-8. PMID 17065026 DOI: 10.1080/10428190600758686  0.161
2020 Odabashian M, Carlotti E, Araf S, Okosun J, Spada F, Gribben JG, Forconi F, Stevenson FK, Calaminici M, Krysov S. IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution. Blood. 135: 834-844. PMID 31932843 DOI: 10.1182/blood.2019002279  0.16
2016 McCann KJ, Mander A, Cazaly A, Chudley L, Stasakova J, Thirdborough SM, King A, Lloyd-Evans P, Buxton E, Edwards C, Halford S, Bateman A, O'Callaghan A, Clive S, Anthoney A, ... ... Stevenson FK, et al. Targeting Carcinoembryonic Antigen with DNA Vaccination: On-Target Adverse Events Link with Immunological and Clinical Outcomes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27091407 DOI: 10.1158/1078-0432.CCR-15-2507  0.16
2008 Rice J, Ottensmeier CH, Stevenson FK. DNA vaccines: precision tools for activating effective immunity against cancer. Nature Reviews. Cancer. 8: 108-20. PMID 18219306 DOI: 10.1038/nrc2326  0.16
1997 Stevenson FK, Silverman GJ. Expression of anti-DNA antibodies. Lupus. 6: 321-3. PMID 9296777 DOI: 10.1177/096120339700600322  0.16
2016 Bollard CM, Stevenson FK. Introduction to a review series on advances in cell-based immune therapeutics in hematology. Blood. 127: 3293. PMID 27207803 DOI: 10.1182/blood-2016-05-713255  0.159
1993 Potter KN, Li Y, Pascual V, Williams RC, Byres LC, Spellerberg M, Stevenson FK, Capra JD. Molecular characterization of a cross-reactive idiotope on human immunoglobulins utilizing the VH4-21 gene segment. The Journal of Experimental Medicine. 178: 1419-28. PMID 8376944  0.159
2015 Li Causi E, Parikh SC, Chudley L, Layfield DM, Ottensmeier CH, Stevenson FK, Di Genova G. Vaccination Expands Antigen-Specific CD4+ Memory T Cells and Mobilizes Bystander Central Memory T Cells. Plos One. 10: e0136717. PMID 26332995 DOI: 10.1371/journal.pone.0136717  0.158
2022 Arthur R, Wathen A, Lemm EA, Stevenson FK, Forconi F, Linley AJ, Steele AJ, Packham G, Valle-Argos B. BTK-independent regulation of calcium signalling downstream of the B-cell receptor in malignant B-cells. Cellular Signalling. 96: 110358. PMID 35597428 DOI: 10.1016/j.cellsig.2022.110358  0.156
1986 Walters MT, Stevenson FK, Herbert A, Cawley MI, Smith JL. Urinary monoclonal free light chains in primary Sjögren's syndrome: an aid to the diagnosis of malignant lymphoma. Annals of the Rheumatic Diseases. 45: 210-9. PMID 3082300 DOI: 10.1136/ard.45.3.210  0.156
2018 Allen A, Wang C, Caproni LJ, Sugiyarto G, Harden E, Douglas LR, Duriez PJ, Karbowniczek K, Extance J, Rothwell PJ, Orefo I, Tite JP, Stevenson FK, Ottensmeier CH, Savelyeva N. Linear doggybone DNA vaccine induces similar immunological responses to conventional plasmid DNA independently of immune recognition by TLR9 in a pre-clinical model. Cancer Immunology, Immunotherapy : Cii. PMID 29330557 DOI: 10.1007/s00262-017-2111-y  0.156
2006 McCann KJ, Johnson PW, Stevenson FK, Ottensmeier CH. Universal N-glycosylation sites introduced into the B-cell receptor of follicular lymphoma by somatic mutation: a second tumorigenic event? Leukemia. 20: 530-4. PMID 16437152 DOI: 10.1038/sj.leu.2404095  0.155
1995 Børretzen M, Chapman C, Stevenson FK, Natvig JB, Thompson KM. Structural analysis of VH4-21 encoded human IgM allo- and autoantibodies against red blood cells. Scandinavian Journal of Immunology. 42: 90-7. PMID 7631150  0.155
1967 Stevenson FK, Stevenson GT. Antibody activity in the presence of urea or guanidine. Biochimica Et Biophysica Acta. 133: 162-4. PMID 6047649 DOI: 10.1016/0005-2795(67)90049-9  0.155
1989 Hamblin TJ, Inzani V, Sadullah S, Stevenson FK, Williamson P, van der Plas J, Palmer P, Franks CR. A phase-II trial of recombinant interleukin-2 and 5-FU chemotherapy in patients with metastatic colorectal carcinoma. Cancer Treatment Reviews. 163-7. PMID 2670212 DOI: 10.1016/0305-7372(89)90037-6  0.154
2002 Potter KN, Hobby P, Klijn S, Stevenson FK, Sutton BJ. Evidence for involvement of a hydrophobic patch in framework region 1 of human V4-34-encoded Igs in recognition of the red blood cell I antigen. Journal of Immunology (Baltimore, Md. : 1950). 169: 3777-82. PMID 12244172 DOI: 10.4049/jimmunol.169.7.3777  0.154
2015 Blunt MD, Carter MJ, Larrayoz M, Smith LD, Aguilar-Hernandez M, Cox KL, Tipton T, Reynolds M, Murphy S, Lemm E, Dias S, Duncombe A, Strefford JC, Johnson PW, Forconi F, ... Stevenson FK, et al. The PI3K/mTOR inhibitor PF-04691502 induces apoptosis and inhibits microenvironmental signaling in CLL and the Eµ-TCL1 mouse model. Blood. 125: 4032-41. PMID 25957390 DOI: 10.1182/blood-2014-11-610329  0.152
2002 Hamblin TJ, Orchard JA, Ibbotson RE, Davis Z, Thomas PW, Stevenson FK, Oscier DG. CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood. 99: 1023-9. PMID 11807008  0.15
2016 D'Avola A, Drennan S, Tracy I, Henderson I, Chiecchio L, Larrayoz M, Rose-Zerilli M, Strefford J, Plass C, Johnson PW, Steele AJ, Packham G, Stevenson FK, Oakes CC, Forconi F. Surface IgM expression and function associate with clinical behavior, genetic abnormalities and DNA methylation in CLL. Blood. PMID 27301861 DOI: 10.1182/Blood-2016-03-707786  0.15
2000 Stevenson FK, Zhu D, Spellerberg MB, Rice J, King CA, Thompsett AR, Sahota SS, Hamblin TJ. DNA vaccination against cancer antigens. Ernst Schering Research Foundation Workshop. 119-36. PMID 10943320 DOI: 10.1007/978-3-662-04183-3_8  0.147
1972 Stevenson FK. The immunological demonstration of an association between maltase activity and proximal tubular cell borders in the rabbit kidney. Biochimica Et Biophysica Acta. 282: 226-33. PMID 4115987 DOI: 10.1016/0005-2736(72)90328-8  0.146
2017 Stevenson FK, Bollard CM. Introduction to a review series on therapeutic antibodies. Blood. 131: 1. PMID 29118004 DOI: 10.1182/blood-2017-10-798769  0.145
1978 Hough DW, Chapple JC, Stevenson FK, Stevenson GT. Further studies of immunoglobulin synthesis by guinea pig leukaemic lymphocytes. Immunology. 34: 889-99. PMID 96010  0.144
2007 Pickering BM, de Mel S, Lee M, Howell M, Habens F, Dallman CL, Neville LA, Potter KN, Mann J, Mann DA, Johnson PW, Stevenson FK, Packham G. Pharmacological inhibitors of NF-kappaB accelerate apoptosis in chronic lymphocytic leukaemia cells. Oncogene. 26: 1166-77. PMID 16924235 DOI: 10.1038/sj.onc.1209897  0.144
2012 Stevenson FK. Turning genes into cancer vaccines. Discovery Medicine. 5: 37-42. PMID 20704921  0.144
1991 Mageed RA, MacKenzie LE, Stevenson FK, Yuksel B, Shokri F, Maziak BR, Jefferis R, Lydyard PM. Selective expression of a VHIV subfamily of immunoglobulin genes in human CD5+ B lymphocytes from cord blood. The Journal of Experimental Medicine. 174: 109-13. PMID 1711557  0.143
2004 McCarthy H, Ottensmeier CH, Hamblin TJ, Stevenson FK. Anti-idiotype vaccines. British Journal of Haematology. 123: 770-81. PMID 14632768 DOI: 10.1046/j.1365-2141.2003.04698.x  0.141
1988 Smith JL, Oscier DG, Haegert DG, Jones DB, Howell M, Hodges E, Stevenson FK, Hamblin TJ. CD3+ CD8+ T cell lymphocytosis masking B cell leukaemia. Journal of Clinical Pathology. 41: 746-52. PMID 3261739  0.14
2014 Stevenson FK, Smith JL. Chronic lymphocytic leukaemia and normal B lymphopoiesis. Immunology Today. 5: 60. PMID 25291511 DOI: 10.1016/0167-5699(84)90163-4  0.139
2003 Potter KN, Orchard J, Critchley E, Mockridge CI, Jose A, Stevenson FK. Features of the overexpressed V1-69 genes in the unmutated subset of chronic lymphocytic leukemia are distinct from those in the healthy elderly repertoire. Blood. 101: 3082-4. PMID 12480699 DOI: 10.1182/blood-2002-08-2432  0.134
2008 Furmanski AL, Ferreira C, Bartok I, Dimakou S, Rice J, Stevenson FK, Millrain MM, Simpson E, Dyson J. Public T cell receptor beta-chains are not advantaged during positive selection. Journal of Immunology (Baltimore, Md. : 1950). 180: 1029-39. PMID 18178843 DOI: 10.4049/jimmunol.180.2.1029  0.134
1977 Stevenson GT, Elliott EV, Stevenson FK. Idiotypic determinants on the surface immunoglobulin of neoplastic lymphocytes: a therapeutic target. Federation Proceedings. 36: 2268-71. PMID 69552  0.131
1994 Roelcke D, Kreft H, Hack H, Stevenson FK. Anti-j: human cold agglutinins recognizing linear (i) and branched (I) type 2 chains. Vox Sanguinis. 67: 216-21. PMID 7801615  0.129
2003 Jardin F, Bastard C, Contentin N, Parmentier F, Picquenot JM, Tilly H, Stevenson FK, Sahota SS. Intronic BCL-6 mutations are preferentially targeted to the translocated allele in t(3;14)(q27;q32) non-Hodgkin B-cell lymphoma. Blood. 102: 1872-6. PMID 12775568 DOI: 10.1182/blood-2002-12-3630  0.129
2014 Stevenson FK. Idiotypes and diseases. Immunology Today. 7: 287-8. PMID 25290840 DOI: 10.1016/0167-5699(86)90059-9  0.129
1998 Snow RE, Chapman CJ, Holgate ST, Stevenson FK. Clonally related IgE and IgG4 transcripts in blood lymphocytes of patients with asthma reveal differing patterns of somatic mutation. European Journal of Immunology. 28: 3354-61. PMID 9808205 DOI: 10.1002/(SICI)1521-4141(199810)28:10<3354::AID-IMMU3354>3.0.CO;2-Z  0.128
2008 Thirdborough SM, Roddick JS, Radcliffe JN, Howarth M, Stevenson FK, Elliott T. Tapasin shapes immunodominance hierarchies according to the kinetic stability of peptide-MHC class I complexes. European Journal of Immunology. 38: 364-9. PMID 18196518 DOI: 10.1002/Eji.200737832  0.126
1993 Deane M, Mackenzie LE, Stevenson FK, Youinou PY, Lydyard PM, Mageed RA. The genetic basis of human VH4 gene family-associated cross-reactive idiotype expression in CD5+ and CD5- cord blood B-lymphocyte clones. Scandinavian Journal of Immunology. 38: 348-58. PMID 7692592  0.126
2016 Blunt MD, Koehrer S, Dobson R, Larrayoz M, Wilmore S, Hayman A, Parnell J, Smith LD, Davies A, Johnson PW, Conley PB, Pandey A, Strefford JC, Stevenson FK, Packham G, et al. The dual Syk/JAK inhibitor cerdulatinib antagonises B-cell receptor and microenvironmental signaling in chronic lymphocytic leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27697994 DOI: 10.1158/1078-0432.CCR-16-1662  0.126
1991 Pascual V, Victor K, Lelsz D, Spellerberg MB, Hamblin TJ, Thompson KM, Randen I, Natvig J, Capra JD, Stevenson FK. Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype. Journal of Immunology (Baltimore, Md. : 1950). 146: 4385-91. PMID 1710250  0.125
2004 Stevenson FK, Rice J, Zhu D. Tumor vaccines. Advances in Immunology. 82: 49-103. PMID 14975255 DOI: 10.1016/S0065-2776(04)82002-9  0.125
2004 Savelyeva N, Zhu D, Stevenson FK. Engineering DNA vaccines that include plant virus coat proteins. Biotechnology & Genetic Engineering Reviews. 20: 101-14. PMID 14997848 DOI: 10.1080/02648725.2003.10648039  0.122
2024 Steidl C, Stevenson FK. Introduction to a review series on the influence of the tumor microenvironment on the pathogenesis of B-cell lymphomas. Blood. 143: 1057-1058. PMID 38512261 DOI: 10.1182/blood.2023021003  0.12
2000 Stevenson FK, Anderson KC. Preparing the ground for vaccination against multiple myeloma. Immunology Today. 21: 170-1. PMID 10798849 DOI: 10.1016/s0167-5699(99)01579-0  0.118
2010 Stevenson FK, Johnson PW. Harnessing innate immunity to suppress lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4295-6. PMID 20697076 DOI: 10.1200/JCO.2010.30.4212  0.117
1975 Stevenson GT, Eady RP, Hough DW, Jurd RD, Stevenson FK. Surface immunoglobulin of guinea-pig leukaemic lymphocytes. Immunology. 28: 807-20. PMID 48498  0.115
1978 Stevenson FK, Cleeter MW, Stevenson GT. beta2-Microglobulin from normal and leukaemic guinea-pig lymphocytes. Scandinavian Journal of Immunology. 8: 127-34. PMID 81517 DOI: 10.1111/j.1365-3083.1978.tb00504.x  0.114
2000 Hamblin TJ, Orchard JA, Gardiner A, Oscier DG, Davis Z, Stevenson FK. Immunoglobulin V genes and CD38 expression in CLL. Blood. 95: 2455-7. PMID 10787241  0.113
2016 Drennan S, D'Avola A, Gao Y, Weigel C, Chrysostomou E, Steele AJ, Zenz T, Plass C, Johnson PW, Williams AP, Packham G, Stevenson FK, Oakes CC, Forconi F. IL-10 production by CLL cells is enhanced in the anergic IGHV mutated subset and associates with reduced DNA methylation of the IL10 locus. Leukemia. PMID 27890932 DOI: 10.1038/Leu.2016.356  0.112
2004 Stevenson FK. DNA vaccines and adjuvants. Immunological Reviews. 199: 5-8. PMID 15233722 DOI: 10.1111/j.0105-2896.2004.00146.x  0.112
2015 Pepper C, Buggins AG, Jones CH, Walsby EJ, Forconi F, Pratt G, Devereux S, Stevenson FK, Fegan C. Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition. Leukemia. 29: 744-7. PMID 25349153 DOI: 10.1038/leu.2014.308  0.109
2015 Schneider D, Dühren-von Minden M, Alkhatib A, Setz C, van Bergen CA, Benkißer-Petersen M, Wilhelm I, Villringer S, Krysov S, Packham G, Zirlik K, Römer W, Buske C, Stevenson FK, Veelken H, et al. Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma. Blood. 125: 3287-96. PMID 25784678 DOI: 10.1182/blood-2014-11-609404  0.109
1997 Zhu D, Spellerberg MB, Thompsett A, King CA, Hamblin TJ, Stevenson FK. DNA vaccination as cancer immunotherapy. Biochemical Society Transactions. 25: 743-7. PMID 9191196 DOI: 10.1042/bst0250743  0.108
1980 Glennie M, Stevenson FK, Stevenson GT, Virji M. Cross-linking of lymphocytic surface immunoglobulin inhibits its production via a cyclic nucleotide mechanism. Nature. 281: 305-7. PMID 233126 DOI: 10.1038/281305a0  0.104
1990 Bell AJ, North J, Stevenson FK, Hamblin TJ. Peripheral blood stem cell autografts in myeloma Bone Marrow Transplantation. 5: 52-54. PMID 1969314  0.103
1997 Snow RE, Chapman CJ, Frew AJ, Holgate ST, Stevenson FK. Pattern of usage and somatic hypermutation in the V(H)5 gene segments of a patient with asthma: Implications for IgE European Journal of Immunology. 27: 162-170. PMID 9022013 DOI: 10.1002/eji.1830270124  0.095
2018 Stevenson FK. Introduction to a review series on biological insights into lymphoid tumors. Blood. 131: 2275. PMID 29666113 DOI: 10.1182/blood-2018-01-824052  0.092
2010 Stevenson FK, Palucka K. Understanding and activating immunity against human cancer. Current Opinion in Immunology. 22: 212-4. PMID 20338741 DOI: 10.1016/j.coi.2010.03.001  0.092
1990 George AJ, Stevenson FK. Humoral effector mechanisms in the immunity to cancer. Immunology Today. 11: 348-9. PMID 2222758 DOI: 10.1016/0167-5699(90)90138-y  0.091
1973 Stevenson FK. Studies on the cell surface maltase of the rabbit renal cortex. Biochimica Et Biophysica Acta. 311: 409-16. PMID 4199706 DOI: 10.1016/0005-2736(73)90321-0  0.09
1990 Walters MT, Stevenson FK, Goswami R, Smith JL, Cawley MI. Comparison of serum and synovial fluid concentrations of beta 2-microglobulin and C reactive protein in relation to clinical disease activity and synovial inflammation in rheumatoid arthritis. Annals of the Rheumatic Diseases. 48: 905-11. PMID 2512862 DOI: 10.1136/ard.48.11.905  0.083
2023 Bryant D, Smith L, Rogers-Broadway KR, Karydis L, Woo J, Blunt MD, Forconi F, Stevenson FK, Goodnow C, Russell A, Humburg P, Packham G, Steele AJ, Strefford JC. Network analysis reveals a major role for 14q32 cluster miRNAs in determining transcriptional differences between IGHV-mutated and unmutated CLL. Leukemia. PMID 37169950 DOI: 10.1038/s41375-023-01918-9  0.08
2017 Kipps TJ, Stevenson FK, Wu CJ, Croce CM, Packham G, Wierda WG, O'Brien S, Gribben J, Rai K. Chronic lymphocytic leukaemia. Nature Reviews. Disease Primers. 3: 17008. PMID 28179635 DOI: 10.1038/nrdp.2017.8  0.078
1988 Stevenson GT, Glennie MJ, Hamblin TJ, Lane AC, Stevenson FK. Problems and prospects in the use of lymphoma idiotypes as therapeutic targets International Journal of Cancer. 42: 9-12. PMID 3209307  0.074
2019 Smith LD, Minton AR, Blunt MD, Karydis LI, Dutton DA, Rogers-Broadway KR, Dobson R, Liu R, Norster F, Hogg E, Ashton-Key M, Strefford JC, Jia L, Efremov DG, Helgason GV, ... ... Stevenson FK, et al. BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia. Leukemia. PMID 31462734 DOI: 10.1038/s41375-019-0557-y  0.074
2002 Stevenson FK, Anderson KC. Immunotherapy for multiple myeloma: insights from other models. Leukemia Research. 26: 403-5. PMID 11839385 DOI: 10.1016/s0145-2126(01)00143-6  0.068
2015 Linley A, Valle-Argos B, Steele AJ, Stevenson FK, Forconi F, Packham G. Higher levels of reactive oxygen species are associated with anergy in chronic lymphocytic leukemia. Haematologica. PMID 25749826 DOI: 10.3324/haematol.2014.120824  0.067
2021 Roberts AW, Stevenson FK. Introduction to a review series on small molecule targeted therapies for lymphoid malignancies. Blood. PMID 34320159 DOI: 10.1182/blood.2021012674  0.062
2020 Bollard CM, Stevenson FK. Introduction to a review series on understanding and treating primary immunodeficiency. Blood. 135: 591. PMID 31942630 DOI: 10.1182/blood.2019004081  0.061
1970 Stevenson FK, Kent PW. Subunits of Tamm-Horsfall glycoprotein. The Biochemical Journal. 116: 791-6. PMID 5441368 DOI: 10.1042/bj1160791  0.052
1995 Stevenson FK. Hodgkin's disease--new insights from immunoglobulin genetics. The New England Journal of Medicine. 333: 934-6. PMID 7545267 DOI: 10.1056/NEJM199510053331411  0.048
1996 Stevenson FK, Snow RE, Chapman CJ, Frew AJ, Holgate ST. Genetic analysis of IgE. Thorax. 51: 458-60. PMID 8711670  0.044
1967 Stevenson FK, Kent PW, Fisher D. Quantitative determination of xylose in mucopolysaccharide derivatives. Chemistry & Industry. 17: 703-4. PMID 4227325  0.042
1972 Stevenson FK. The disaccharidase activity of a membrane fraction obtained from the rabbit renal cortex. Biochimica Et Biophysica Acta. 266: 144-53. PMID 5041085 DOI: 10.1016/0005-2736(72)90130-7  0.028
1969 Stevenson FK. The viscosity of Tamm-Horsfall mucoprotein and its relation to cystic fibrosis. Clinica Chimica Acta; International Journal of Clinical Chemistry. 23: 441-7. PMID 5794481 DOI: 10.1016/0009-8981(69)90346-5  0.021
1971 Stevenson FK, Cleave AJ, Kent PW. The effect of ions on the viscometric and ultracentrifugal behaviour of Tamm-Horsfall glycoprotein. Biochimica Et Biophysica Acta. 236: 59-66. PMID 5577473 DOI: 10.1016/0005-2795(71)90149-8  0.02
1968 Stevenson FK. The viscosity of Tamm-Horsfall mucoprotein. Biochimica Et Biophysica Acta. 160: 296-8. PMID 5658139 DOI: 10.1016/0005-2795(68)90111-6  0.011
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