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Matthew T. Eddy - Publications

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Anazia K, Koenekoop L, Ferré G, Petracco E, Gutiérrez-de-Teran H, Eddy MT. Interaction Networks within Disease-Associated Gα Variants Characterized by an Integrative Biophysical Approach. The Journal of Biological Chemistry. 107497. PMID 38925329 DOI: 10.1016/j.jbc.2024.107497  0.371
2024 Anazia K, Koenekoop L, Ferré G, Petracco E, Gutiérrez-de-Teran H, Eddy MT. Visualizing the impact of disease-associated mutations on G protein-nucleotide interactions. Biorxiv : the Preprint Server For Biology. PMID 38352316 DOI: 10.1101/2024.01.30.578006  0.34
2023 Jin B, Thakur N, Wijesekara AV, Eddy MT. Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled receptors. Current Opinion in Pharmacology. 102364. PMID 37612173 DOI: 10.1016/j.coph.2023.102364  0.508
2023 Thakur N, Ray AP, Sharp L, Jin B, Duong A, Pour NG, Obeng S, Wijesekara AV, Gao ZG, McCurdy CR, Jacobson KA, Lyman E, Eddy MT. Anionic phospholipids control mechanisms of GPCR-G protein recognition. Nature Communications. 14: 794. PMID 36781870 DOI: 10.1038/s41467-023-36425-z  0.434
2023 Thakur N, Ray AP, Sharp L, Jin B, Duong A, Pour NG, Obeng S, Wijesekara AV, Gao ZG, McCurdy CR, Jacobson KA, Lyman E, Eddy MT. Anionic Phospholipids Control Mechanisms of GPCR-G Protein Recognition. Biorxiv : the Preprint Server For Biology. PMID 36711594 DOI: 10.1101/2023.01.11.523010  0.433
2022 Ferré G, Anazia K, Silva LO, Thakur N, Ray AP, Eddy MT. Global insights into the fine tuning of human AAR conformational dynamics in a ternary complex with an engineered G protein viewed by NMR. Cell Reports. 41: 111844. PMID 36543140 DOI: 10.1016/j.celrep.2022.111844  0.462
2021 Wei S, Thakur N, Ray AP, Jin B, Obeng S, McCurdy CR, McMahon LR, Gutiérrez-de-Terán H, Eddy MT, Lamichhane R. Slow conformational dynamics of the human A adenosine receptor are temporally ordered. Structure (London, England : 1993). PMID 34895472 DOI: 10.1016/j.str.2021.11.005  0.314
2021 Mulry E, Ray AP, Eddy MT. Production of a Human Histamine Receptor for NMR Spectroscopy in Aqueous Solutions. Biomolecules. 11. PMID 33923140 DOI: 10.3390/biom11050632  0.488
2020 Eddy MT, Martin BT, Wüthrich K. A Adenosine Receptor Partial Agonism Related to Structural Rearrangements in an Activation Microswitch. Structure (London, England : 1993). PMID 33238145 DOI: 10.1016/j.str.2020.11.005  0.462
2020 Ferré G, Eddy M. Structural Biology of Human GPCR Drugs and Endogenous Ligands - Insights from NMR Spectroscopy. Methods (San Diego, Calif.). PMID 32911074 DOI: 10.1016/j.ymeth.2020.08.008  0.387
2019 Eddy MT, Yu TY, Wagner G, Griffin RG. Structural characterization of the human membrane protein VDAC2 in lipid bilayers by MAS NMR. Journal of Biomolecular Nmr. PMID 31407201 DOI: 10.1007/S10858-019-00242-8  0.386
2019 Eddy MT. Studying Structural Plasticity Underlying GPCR Function Biophysical Journal. 116: 176a. DOI: 10.1016/J.Bpj.2018.11.978  0.351
2018 Sušac L, Eddy MT, Didenko T, Stevens RC, Wüthrich K. A adenosine receptor functional states characterized by F-NMR. Proceedings of the National Academy of Sciences of the United States of America. PMID 30463958 DOI: 10.1073/Pnas.1813649115  0.657
2018 Shimada I, Ueda T, Kofuku Y, Eddy MT, Wüthrich K. GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures. Nature Reviews. Drug Discovery. PMID 30410121 DOI: 10.1038/Nrd.2018.180  0.526
2018 Eddy MT, Gao ZG, Mannes P, Patel N, Jacobson KA, Katritch V, Stevens RC, Wüthrich K. Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor. Journal of the American Chemical Society. PMID 29874058 DOI: 10.1021/Jacs.8B03805  0.715
2018 White KL, Eddy MT, Gao ZG, Han GW, Lian T, Deary A, Patel N, Jacobson KA, Katritch V, Stevens RC. Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling. Structure (London, England : 1993). PMID 29395784 DOI: 10.1016/J.Str.2017.12.013  0.708
2017 Eddy MT, Lee MY, Gao ZG, White KL, Didenko T, Horst R, Audet M, Stanczak P, McClary KM, Han GW, Jacobson KA, Stevens RC, Wüthrich K. Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor. Cell. PMID 29290469 DOI: 10.1016/J.Cell.2017.12.004  0.59
2016 Eddy MT, Didenko T, Stevens RC, Wüthrich K. β2-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop. Structure (London, England : 1993). 24: 2190-2197. PMID 27839952 DOI: 10.1016/J.Str.2016.09.015  0.651
2015 Andreas LB, Reese M, Eddy MT, Gelev V, Ni QZ, Miller EA, Emsley L, Pintacuda G, Chou JJ, Griffin RG. Structure and Mechanism of the Influenza A M218-60 Dimer of Dimers. Journal of the American Chemical Society. PMID 26218479 DOI: 10.1021/Jacs.5B04802  0.48
2015 Eddy MT, Su Y, Silvers R, Andreas L, Clark L, Wagner G, Pintacuda G, Emsley L, Griffin RG. Lipid bilayer-bound conformation of an integral membrane beta barrel protein by multidimensional MAS NMR. Journal of Biomolecular Nmr. 61: 299-310. PMID 25634301 DOI: 10.1007/S10858-015-9903-1  0.457
2015 Eddy MT, Andreas L, Teijido O, Su Y, Clark L, Noskov SY, Wagner G, Rostovtseva TK, Griffin RG. Magic angle spinning nuclear magnetic resonance characterization of voltage-dependent anion channel gating in two-dimensional lipid crystalline bilayers. Biochemistry. 54: 994-1005. PMID 25545271 DOI: 10.1021/Bi501260R  0.402
2014 Eddy MT, Yu TY. Membranes, peptides, and disease: unraveling the mechanisms of viral proteins with solid state nuclear magnetic resonance spectroscopy. Solid State Nuclear Magnetic Resonance. 61: 1-7. PMID 24837131 DOI: 10.1016/J.Ssnmr.2014.04.002  0.317
2014 Su Y, Sarell CJ, Eddy MT, Debelouchina GT, Andreas LB, Pashley CL, Radford SE, Griffin RG. Secondary structure in the core of amyloid fibrils formed from human β₂m and its truncated variant ΔN6. Journal of the American Chemical Society. 136: 6313-25. PMID 24679070 DOI: 10.1021/Ja4126092  0.357
2014 Hermida OT, Noskov SY, Ujwal R, Abramson J, Eddy MT, Griffin RG, Bezrukov SM, Rostovtseva TK. Functional, Structural, and Computational Approaches to the Molecular Mechanism of Vdac Gating Biophysical Journal. 106: 590a. DOI: 10.1016/J.Bpj.2013.11.3270  0.357
2013 Eddy MT, Belenky M, Sivertsen AC, Griffin RG, Herzfeld J. Selectively dispersed isotope labeling for protein structure determination by magic angle spinning NMR. Journal of Biomolecular Nmr. 57: 129-39. PMID 23990199 DOI: 10.1007/S10858-013-9773-3  0.401
2013 Daviso E, Eddy MT, Andreas LB, Griffin RG, Herzfeld J. Efficient resonance assignment of proteins in MAS NMR by simultaneous intra- and inter-residue 3D correlation spectroscopy. Journal of Biomolecular Nmr. 55: 257-65. PMID 23334347 DOI: 10.1007/S10858-013-9707-0  0.42
2012 Andreas LB, Eddy MT, Chou JJ, Griffin RG. Magic-angle-spinning NMR of the drug resistant S31N M2 proton transporter from influenza A. Journal of the American Chemical Society. 134: 7215-8. PMID 22480220 DOI: 10.1021/Ja3003606  0.418
2012 Eddy MT, Ong TC, Clark L, Teijido O, van der Wel PC, Garces R, Wagner G, Rostovtseva TK, Griffin RG. Lipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1. Journal of the American Chemical Society. 134: 6375-87. PMID 22435461 DOI: 10.1021/Ja300347V  0.44
2011 Bayro MJ, Debelouchina GT, Eddy MT, Birkett NR, MacPhee CE, Rosay M, Maas WE, Dobson CM, Griffin RG. Intermolecular structure determination of amyloid fibrils with magic-angle spinning and dynamic nuclear polarization NMR. Journal of the American Chemical Society. 133: 13967-74. PMID 21774549 DOI: 10.1021/Ja203756X  0.395
2011 De Paëpe G, Lewandowski JR, Loquet A, Eddy M, Megy S, Böckmann A, Griffin RG. Heteronuclear proton assisted recoupling. The Journal of Chemical Physics. 134: 095101. PMID 21384999 DOI: 10.1063/1.3541251  0.376
2011 Hermida OT, Eddy MT, Griffin RG, Bezrukov S, Rostovtseva TK. Probing VDAC Voltage-Gating Mechanism by pH: Functional and Structural Implications Biophysical Journal. 100: 41a-42a. DOI: 10.1016/J.Bpj.2010.12.428  0.353
2011 Eddy MT, Hermida OT, Andreas L, Wagner G, Rostovtseva TK, Griffin RG. Investigating VDAC Gating via Magic Angle Spinning NMR and Electrophysiological Measurements Under Extreme pH Conditions: Implications for the Voltage-Gating Mechanism Biophysical Journal. 100: 8a-9a. DOI: 10.1016/J.Bpj.2010.12.258  0.434
2010 Matsuki Y, Eddy MT, Griffin RG, Herzfeld J. Rapid three-dimensional MAS NMR spectroscopy at critical sensitivity. Angewandte Chemie (International Ed. in English). 49: 9215-8. PMID 20957710 DOI: 10.1002/Anie.201003329  0.463
2010 Andreas LB, Eddy MT, Pielak RM, Chou J, Griffin RG. Magic angle spinning NMR investigation of influenza A M2(18-60): support for an allosteric mechanism of inhibition. Journal of the American Chemical Society. 132: 10958-60. PMID 20698642 DOI: 10.1021/Ja101537P  0.392
2009 van der Wel PC, Eddy MT, Ramachandran R, Griffin RG. Targeted 13C-13C distance measurements in a microcrystalline protein via J-decoupled rotational resonance width measurements. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 10: 1656-63. PMID 19565580 DOI: 10.1002/Cphc.200900102  0.396
2009 Lewandowski JR, De Paëpe G, Eddy MT, Struppe J, Maas W, Griffin RG. Proton assisted recoupling at high spinning frequencies. The Journal of Physical Chemistry. B. 113: 9062-9. PMID 19489532 DOI: 10.1021/Jp810280T  0.347
2009 Lewandowski JR, De Paëpe G, Eddy MT, Griffin RG. (15)N-(15)N proton assisted recoupling in magic angle spinning NMR. Journal of the American Chemical Society. 131: 5769-76. PMID 19334788 DOI: 10.1021/Ja806578Y  0.385
2009 Matsuki Y, Eddy MT, Herzfeld J. Spectroscopy by integration of frequency and time domain information for fast acquisition of high-resolution dark spectra. Journal of the American Chemical Society. 131: 4648-56. PMID 19284727 DOI: 10.1021/Ja807893K  0.313
2009 Eddy M, Garces R, van der Wel PC, Wagner G, Griffin R. Magic Angle Spinning NMR Investigations of the Human Voltage Dependent Anion Channel Biophysical Journal. 96: 410a. DOI: 10.1016/J.Bpj.2008.12.2090  0.489
2008 Bayro MJ, Ramachandran R, Caporini MA, Eddy MT, Griffin RG. Radio frequency-driven recoupling at high magic-angle spinning frequencies: homonuclear recoupling sans heteronuclear decoupling. The Journal of Chemical Physics. 128: 052321. PMID 18266438 DOI: 10.1063/1.2834736  0.313
2008 Mehta MA, Eddy MT, McNeill SA, Mills FD, Long JR. Determination of peptide backbone torsion angles using double-quantum dipolar recoupling solid-state NMR spectroscopy. Journal of the American Chemical Society. 130: 2202-12. PMID 18220389 DOI: 10.1021/Ja074244W  0.387
2004 Mehta MA, Fry EA, Eddy MT, Dedeo MT, Anagnost AE, Long JR. Structure of the alanine dipeptide in condensed phases determined by 13C NMR Journal of Physical Chemistry B. 108: 2777-2780. DOI: 10.1021/Jp037871Q  0.373
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