| Year |
Citation |
Score |
| 2021 |
Kalathiya U, Padariya M, Faktor J, Coyaud E, Alfaro JA, Fahraeus R, Hupp TR, Goodlett DR. Interfaces with Structure Dynamics of the Workhorses from Cells Revealed through Cross-Linking Mass Spectrometry (CLMS). Biomolecules. 11. PMID 33806612 DOI: 10.3390/biom11030382 |
0.49 |
|
| 2020 |
Bibi N, Hupp T, Kamal MA, Rashid S. Elucidation of PLK1 Linked Biomarkers in Oesophageal Cancer Cell Lines: A Step Towards Novel Signaling Pathways by p53 and PLK1- Linked Functions Crosstalk. Protein and Peptide Letters. PMID 32875973 DOI: 10.2174/0929866527999200901201837 |
0.378 |
|
| 2020 |
Faktor J, Grasso G, Zavadil F, Kurkowiak M, Mayordomo MY, Kote S, Singh A, Ruidong L, O'Neill JR, Muller P, Goodlett D, Vojtesek B, Hupp T. The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model. Biochimica Et Biophysica Acta. General Subjects. 129722. PMID 32866596 DOI: 10.1016/J.Bbagen.2020.129722 |
0.547 |
|
| 2019 |
Urban-Wojciuk Z, Khan MM, Oyler BL, Fåhraeus R, Marek-Trzonkowska N, Nita-Lazar A, Hupp TR, Goodlett DR. The Role of TLRs in Anti-cancer Immunity and Tumor Rejection. Frontiers in Immunology. 10: 2388. PMID 31695691 DOI: 10.3389/Fimmu.2019.02388 |
0.42 |
|
| 2019 |
Delom F, Mohtar MA, Hupp T, Fessart D. The AGR2 interactome. American Journal of Physiology. Cell Physiology. PMID 31644305 DOI: 10.1152/Ajpcell.00532.2018 |
0.382 |
|
| 2019 |
Kote S, Faktor J, Dapic I, Mayordomo MY, Kocikowski M, Kagansky A, Goodlett D, Vojtesek B, Hupp T, Wilcockson D, Piper R. Analysis of venom sac constituents from the solitary, hunting wasp Cerceris rybyensis. Toxicon : Official Journal of the International Society On Toxinology. PMID 31352010 DOI: 10.1016/J.Toxicon.2019.07.012 |
0.476 |
|
| 2019 |
Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, ... ... Hupp T, et al. Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation. Embo Molecular Medicine. PMID 31040128 DOI: 10.15252/Emmm.201810120 |
0.338 |
|
| 2019 |
Bibi N, Niaz H, Hupp T, Kamal MA, Rashid S. Screening and Identification of PLK1-Polo Box binding peptides by high-throughput sequencing of phage-selected libraries. Protein and Peptide Letters. PMID 30887917 DOI: 10.2174/0929866526666190318101054 |
0.301 |
|
| 2019 |
Nguyen MN, Sen N, Lin MY, Joseph TL, Vaz C, Tanavde V, Way L, Hupp TR, Verma CS, Madhusudhan MS. Discovering Putative Protein Targets of Small Molecules: A Study of the p53 Activator Nutlin. Journal of Chemical Information and Modeling. PMID 30794402 DOI: 10.1021/Acs.Jcim.8B00762 |
0.386 |
|
| 2017 |
Muller P, Chan JM, Simoncik O, Fojta M, Lane DP, Hupp T, Vojtesek B. Evidence for allosteric effects on p53 oligomerization induced by phosphorylation. Protein Science : a Publication of the Protein Society. PMID 29124793 DOI: 10.1002/Pro.3344 |
0.371 |
|
| 2017 |
Landré V, Revi B, Mir MG, Verma C, Hupp TR, Gilbert N, Ball KL. Regulation of transcriptional activators by DNA-binding domain ubiquitination. Cell Death and Differentiation. PMID 28362432 DOI: 10.1038/Cdd.2017.42 |
0.345 |
|
| 2016 |
Way L, Faktor J, Dvorakova P, Nicholson J, Vojtesek B, Graham D, Ball KL, Hupp T. Rearrangement of Mitochondrial Pyruvate Dehydrogenase Subunit Dihydrolipoamide Dehydrogenase Protein-Protein Interactions by the MDM2 Ligand Nutlin-3. Proteomics. PMID 27273042 DOI: 10.1002/Pmic.201500501 |
0.403 |
|
| 2015 |
Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin. Chemical Science. 6: 3109-3116. PMID 28706685 DOI: 10.1039/c4sc03885a |
0.32 |
|
| 2015 |
Krejci A, Hupp TR, Lexa M, Vojtesek B, Muller P. Hammock: a hidden Markov model-based peptide clustering algorithm to identify protein-interaction consensus motifs in large datasets. Bioinformatics (Oxford, England). PMID 26342231 DOI: 10.1093/Bioinformatics/Btv522 |
0.339 |
|
| 2015 |
Dickinson ER, Jurneczko E, Nicholson J, Hupp TR, Zawacka-Pankau J, Selivanova G, Barran PE. The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors. Frontiers in Molecular Biosciences. 2: 39. PMID 26217671 DOI: 10.3389/Fmolb.2015.00039 |
0.363 |
|
| 2015 |
Dickinson ER, Jurneczko E, Pacholarz KJ, Clarke DJ, Reeves M, Ball KL, Hupp T, Campopiano D, Nikolova PV, Barran PE. Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry. Analytical Chemistry. 87: 3231-8. PMID 25629302 DOI: 10.1021/Ac503720V |
0.312 |
|
| 2014 |
Dejeans N, Manié S, Hetz C, Bard F, Hupp T, Agostinis P, Samali A, Chevet E. Addicted to secrete - novel concepts and targets in cancer therapy. Trends in Molecular Medicine. 20: 242-50. PMID 24456621 DOI: 10.1016/J.Molmed.2013.12.003 |
0.379 |
|
| 2014 |
Kofod-Olsen E, Pettersson S, Wallace M, Abduljabar AB, Oster B, Hupp T, Höllsberg P. Human herpesvirus-6B protein U19 contains a p53 BOX I homology motif for HDM2 binding and p53 stabilization. Virology. 448: 33-42. PMID 24314634 DOI: 10.1016/J.Virol.2013.10.002 |
0.385 |
|
| 2013 |
Kofod-Olsen E, Møller JM, Schleimann MH, Bundgaard B, Bak RO, Øster B, Mikkelsen JG, Hupp T, Höllsberg P. Inhibition of p53-dependent, but not p53-independent, cell death by U19 protein from human herpesvirus 6B. Plos One. 8: e59223. PMID 23555634 DOI: 10.1371/Journal.Pone.0059223 |
0.353 |
|
| 2013 |
Pettersson S, Sczaniecka M, McLaren L, Russell F, Gladstone K, Hupp T, Wallace M. Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway. The Biochemical Journal. 450: 523-36. PMID 23252402 DOI: 10.1042/Bj20121249 |
0.345 |
|
| 2013 |
Chevet E, Fessart D, Delom F, Mulot A, Vojtesek B, Hrstka R, Murray E, Gray T, Hupp T. Emerging roles for the pro-oncogenic anterior gradient-2 in cancer development. Oncogene. 32: 2499-509. PMID 22945652 DOI: 10.1038/Onc.2012.346 |
0.419 |
|
| 2013 |
Scotcher J, Clarke DJ, MacKay CL, Hupp T, Sadler PJ, Langridge-Smith PRR. Redox regulation of tumour suppressor protein p53: Identification of the sites of hydrogen peroxide oxidation and glutathionylation Chemical Science. 4: 1257-1269. DOI: 10.1039/C2Sc21702C |
0.381 |
|
| 2012 |
Ponnuswamy A, Hupp T, Fåhraeus R. Concepts in MDM2 Signaling: Allosteric Regulation and Feedback Loops. Genes & Cancer. 3: 291-7. PMID 23150762 DOI: 10.1177/1947601912454140 |
0.415 |
|
| 2012 |
Nicholson J, Neelagandan K, Huart AS, Ball K, Molloy MP, Hupp T. An iTRAQ proteomics screen reveals the effects of the MDM2 binding ligand Nutlin-3 on cellular proteostasis. Journal of Proteome Research. 11: 5464-78. PMID 23039052 DOI: 10.1021/Pr300698D |
0.42 |
|
| 2012 |
Morelli X, Hupp T. Searching for the Holy Grail; protein-protein interaction analysis and modulation. Embo Reports. 13: 877-9. PMID 22986552 DOI: 10.1038/Embor.2012.137 |
0.355 |
|
| 2012 |
Huart AS, MacLaine NJ, Narayan V, Hupp TR. Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth. Plos One. 7: e43391. PMID 22916255 DOI: 10.1371/journal.pone.0043391 |
0.332 |
|
| 2012 |
Gray TA, MacLaine NJ, Michie CO, Bouchalova P, Murray E, Howie J, Hrstka R, Maslon MM, Nenutil R, Vojtesek B, Langdon S, Hayward L, Gourley C, Hupp TR. Anterior Gradient-3: a novel biomarker for ovarian cancer that mediates cisplatin resistance in xenograft models. Journal of Immunological Methods. 378: 20-32. PMID 22361111 DOI: 10.1016/J.Jim.2012.01.013 |
0.413 |
|
| 2012 |
Frame S, Aspinall C, O'Neil R, Hollick J, Taylor S, Hupp T, Blake D, Zheleva DI. Abstract 2814: Potent and selective small molecule inhibitors of polo-like kinase 1: Biological characterization Cancer Research. 72: 2814-2814. DOI: 10.1158/1538-7445.Am2012-2814 |
0.373 |
|
| 2011 |
Clarke DJ, Murray E, Hupp T, Mackay CL, Langridge-Smith PR. Mapping a noncovalent protein-peptide interface by top-down FTICR mass spectrometry using electron capture dissociation. Journal of the American Society For Mass Spectrometry. 22: 1432-40. PMID 21953198 DOI: 10.1007/S13361-011-0155-3 |
0.386 |
|
| 2011 |
Hengel SM, Murray E, Langdon S, Hayward L, O'Donoghue J, Panchaud A, Hupp T, Goodlett DR. Data-independent proteomic screen identifies novel tamoxifen agonist that mediates drug resistance. Journal of Proteome Research. 10: 4567-78. PMID 21936522 DOI: 10.1021/Pr2004117 |
0.543 |
|
| 2011 |
Hollstein M, Hupp T. Chek2ing out the p53 pathway: can Puma lead the way? Cell Cycle (Georgetown, Tex.). 10: 1524. PMID 21478674 DOI: 10.4161/Cc.10.10.15514 |
0.311 |
|
| 2011 |
Scotcher J, Clarke DJ, Weidt SK, Mackay CL, Hupp TR, Sadler PJ, Langridge-Smith PR. Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry. Journal of the American Society For Mass Spectrometry. 22: 888-97. PMID 21472523 DOI: 10.1007/S13361-011-0088-X |
0.306 |
|
| 2010 |
Marcar L, Maclaine NJ, Hupp TR, Meek DW. Mage-A cancer/testis antigens inhibit p53 function by blocking its interaction with chromatin. Cancer Research. 70: 10362-70. PMID 21056992 DOI: 10.1158/0008-5472.CAN-10-1341 |
0.309 |
|
| 2010 |
Maslon MM, Hupp TR. Drug discovery and mutant p53. Trends in Cell Biology. 20: 542-55. PMID 20656489 DOI: 10.1016/j.tcb.2010.06.005 |
0.301 |
|
| 2010 |
Hrstka R, Nenutil R, Fourtouna A, Maslon MM, Naughton C, Langdon S, Murray E, Larionov A, Petrakova K, Muller P, Dixon MJ, Hupp TR, Vojtesek B. The pro-metastatic protein anterior gradient-2 predicts poor prognosis in tamoxifen-treated breast cancers. Oncogene. 29: 4838-47. PMID 20531310 DOI: 10.1038/Onc.2010.228 |
0.347 |
|
| 2010 |
Meek DW, Hupp TR. The regulation of MDM2 by multisite phosphorylation--opportunities for molecular-based intervention to target tumours? Seminars in Cancer Biology. 20: 19-28. PMID 19897041 DOI: 10.1016/j.semcancer.2009.10.005 |
0.3 |
|
| 2009 |
Stevens C, Lin Y, Harrison B, Burch L, Ridgway RA, Sansom O, Hupp T. Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling. The Journal of Biological Chemistry. 284: 334-44. PMID 18974095 DOI: 10.1074/Jbc.M805165200 |
0.377 |
|
| 2008 |
Nelson L, Anderson S, Archibald AL, Rhind S, Lu ZH, Condie A, McIntyre N, Thompson J, Nenutil R, Vojtesek B, Whitelaw CBA, Little TJ, Hupp T. An animal model to evaluate the function and regulation of the adaptively evolving stress protein SEP53 in oesophageal bile damage responses Cell Stress and Chaperones. 13: 375-385. PMID 18465210 DOI: 10.1007/S12192-008-0037-1 |
0.328 |
|
| 2008 |
Lin Y, Stevens C, Hrstka R, Harrison B, Fourtouna A, Pathuri S, Vojtesek B, Hupp T. An alternative transcript from the death-associated protein kinase 1 locus encoding a small protein selectively mediates membrane blebbing. The Febs Journal. 275: 2574-84. PMID 18422656 DOI: 10.1111/J.1742-4658.2008.06404.X |
0.38 |
|
| 2007 |
Little TJ, Nelson L, Hupp T. Adaptive evolution of a stress response protein Plos One. 2. PMID 17925851 DOI: 10.1371/Journal.Pone.0001003 |
0.322 |
|
| 2007 |
Wawrzynow B, Zylicz A, Wallace M, Hupp T, Zylicz M. MDM2 chaperones the p53 tumor suppressor. The Journal of Biological Chemistry. 282: 32603-12. PMID 17848574 DOI: 10.1074/Jbc.M702767200 |
0.405 |
|
| 2007 |
Din S, Lennon AM, Arnott ID, Hupp T, Satsangi J. Technology insight: the application of proteomics in gastrointestinal disease. Nature Clinical Practice. Gastroenterology & Hepatology. 4: 372-85. PMID 17607293 DOI: 10.1038/Ncpgasthep0872 |
0.318 |
|
| 2007 |
Lin Y, Stevens C, Hupp T. Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis. The Journal of Biological Chemistry. 282: 16792-802. PMID 17324927 DOI: 10.1074/Jbc.M611559200 |
0.392 |
|
| 2007 |
Stevens C, Lin Y, Sanchez M, Amin E, Copson E, White H, Durston V, Eccles DM, Hupp T. A germ line mutation in the death domain of DAPK-1 inactivates ERK-induced apoptosis. The Journal of Biological Chemistry. 282: 13791-803. PMID 17244621 DOI: 10.1074/Jbc.M605649200 |
0.302 |
|
| 2004 |
Burch L, Shimizu H, Smith A, Patterson C, Hupp TR. Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein. Journal of Molecular Biology. 337: 129-45. PMID 15001357 DOI: 10.1016/J.Jmb.2004.01.017 |
0.327 |
|
| 2000 |
Webley K, Bond JA, Jones CJ, Blaydes JP, Craig A, Hupp T, Wynford-Thomas D. Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage. Molecular and Cellular Biology. 20: 2803-8. PMID 10733583 DOI: 10.1128/Mcb.20.8.2803-2808.2000 |
0.349 |
|
| 1997 |
Mundt M, Hupp T, Fritsche M, Merkle C, Hansen S, Lane D, Groner B. Protein interactions at the carboxyl terminus of p53 result in the induction of its in vitro transactivation potential Oncogene. 15: 237-244. PMID 9244359 DOI: 10.1038/Sj.Onc.1201174 |
0.386 |
|
| 1995 |
Lane DP, Lu X, Hupp T, Hall PA. The role of the p53 protein in the apoptotic response. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 345: 277-80. PMID 7846126 DOI: 10.1098/Rstb.1994.0106 |
0.307 |
|
| 1995 |
Hupp TR, Lane DP. Regulation of the cryptic sequence-specific DNA-binding function of p53 by protein kinases. Cold Spring Harbor Symposia On Quantitative Biology. 59: 195-206. PMID 7587070 DOI: 10.1101/SQB.1994.059.01.024 |
0.322 |
|
| 1995 |
Cox L, Hupp T, Midgley C, Lane D. A direct effect of activated human p53 on nuclear DNA replication. The Embo Journal. 14: 2099-2105. DOI: 10.1002/J.1460-2075.1995.Tb07201.X |
0.331 |
|
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