| Year |
Citation |
Score |
| 2017 |
Hounsou C, Baehr C, Gasparik V, Alili D, Belhocine A, Rodriguez T, Dupuis E, Roux T, Mann A, Heissler D, Pin JP, Durroux T, Bonnet D, Hibert M. From the Promiscuous Asenapine to Potent Fluorescent Ligands Acting at a Series of Aminergic G Protein Coupled Receptors. Journal of Medicinal Chemistry. PMID 29219316 DOI: 10.1021/acs.jmedchem.7b01220 |
0.497 |
|
| 2015 |
Hoch L, Faure H, Roudaut H, Schoenfelder A, Mann A, Girard N, Bihannic L, Ayrault O, Petricci E, Taddei M, Rognan D, Ruat M. MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1817-29. PMID 25636740 DOI: 10.1096/fj.14-267849 |
0.469 |
|
| 2015 |
Hounsou C, Margathe JF, Oueslati N, Belhocine A, Dupuis E, Thomas C, Mann A, Ilien B, Rognan D, Trinquet E, Hibert M, Pin JP, Bonnet D, Durroux T. Time-resolved FRET binding assay to investigate hetero-oligomer binding properties: proof of concept with dopamine D1/D3 heterodimer. Acs Chemical Biology. 10: 466-74. PMID 25350273 DOI: 10.1021/cb5007568 |
0.463 |
|
| 2013 |
Gorojankina T, Hoch L, Faure H, Roudaut H, Traiffort E, Schoenfelder A, Girard N, Mann A, Manetti F, Solinas A, Petricci E, Taddei M, Ruat M. Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened. Molecular Pharmacology. 83: 1020-9. PMID 23448715 DOI: 10.1124/Mol.112.084590 |
0.454 |
|
| 2012 |
Solinas A, Faure H, Roudaut H, Traiffort E, Schoenfelder A, Mann A, Manetti F, Taddei M, Ruat M. Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity. Journal of Medicinal Chemistry. 55: 1559-71. PMID 22268551 DOI: 10.1021/Jm2013369 |
0.439 |
|
| 2011 |
Cazorla M, Prémont J, Mann A, Girard N, Kellendonk C, Rognan D. Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. The Journal of Clinical Investigation. 121: 1846-57. PMID 21505263 DOI: 10.1172/Jci43992 |
0.453 |
|
| 2011 |
Roudaut H, Traiffort E, Gorojankina T, Vincent L, Faure H, Schoenfelder A, Mann A, Manetti F, Solinas A, Taddei M, Ruat M. Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist. Molecular Pharmacology. 79: 453-60. PMID 21177415 DOI: 10.1124/Mol.110.069708 |
0.369 |
|
| 2010 |
Manetti F, Faure H, Roudaut H, Gorojankina T, Traiffort E, Schoenfelder A, Mann A, Solinas A, Taddei M, Ruat M. Virtual screening-based discovery and mechanistic characterization of the acylthiourea MRT-10 family as smoothened antagonists. Molecular Pharmacology. 78: 658-65. PMID 20664000 DOI: 10.1124/Mol.110.065102 |
0.389 |
|
| 2006 |
Masdeu C, Faure H, Coulombe J, Schoenfelder A, Mann A, Brabet I, Pin JP, Traiffort E, Ruat M. Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15. Biochemical and Biophysical Research Communications. 349: 471-9. PMID 16945339 DOI: 10.1016/J.Bbrc.2006.07.216 |
0.424 |
|
| 2003 |
Hackling A, Ghosh R, Perachon S, Mann A, Höltje HD, Wermuth CG, Schwartz JC, Sippl W, Sokoloff P, Stark H. N-(omega-(4-(2-methoxyphenyl)piperazin-1-yl)alkyl)carboxamides as dopamine D2 and D3 receptor ligands. Journal of Medicinal Chemistry. 46: 3883-99. PMID 12930150 DOI: 10.1021/Jm030836N |
0.491 |
|
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