Christian Kastrup - Publications

Affiliations: 
2003-2008 The University of British Columbia - Okanagan 

14/56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Pompano RR, Chiang AH, Kastrup CJ, Ismagilov RF. Conceptual and Experimental Tools to Understand Spatial Effects and Transport Phenomena in Nonlinear Biochemical Networks Illustrated with Patchy Switching. Annual Review of Biochemistry. 86: 333-356. PMID 28654324 DOI: 10.1146/Annurev-Biochem-060815-014207  0.668
2017 Yeon JH, Mazinani N, Schlappi TS, Chan KY, Baylis JR, Smith SA, Donovan AJ, Kudela D, Stucky GD, Liu Y, Morrissey JH, Kastrup CJ. Localization of Short-Chain Polyphosphate Enhances its Ability to Clot Flowing Blood Plasma. Scientific Reports. 7: 42119. PMID 28186112 DOI: 10.1038/Srep42119  0.342
2015 Hur WS, Mazinani N, Lu XJ, Britton HM, Byrnes JR, Wolberg AS, Kastrup CJ. Coagulation factor XIIIa is inactivated by plasmin. Blood. PMID 26359437 DOI: 10.1182/Blood-2015-07-650713  0.338
2015 Hun Yeon J, Chan KY, Wong TC, Chan K, Sutherland MR, Ismagilov RF, Pryzdial EL, Kastrup CJ. A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli. Scientific Reports. 5: 10274. PMID 25975772 DOI: 10.1038/Srep10274  0.553
2009 Feng S, Pompano RR, Kastrup CJ, Ismagilov RF. Confinement regulates complex biochemical networks: Initiation of blood clotting by "diffusion acting" Biophysical Journal. 97: 2137-2145. PMID 19843446 DOI: 10.1016/J.Bpj.2009.08.004  0.699
2008 Kastrup CJ, Boedicker JQ, Pomerantsev AP, Moayeri M, Bian Y, Pompano RR, Kline TR, Sylvestre P, Shen F, Leppla SH, Tang WJ, Ismagilov RF. Spatial localization of bacteria controls coagulation of human blood by 'quorum acting' Nature Chemical Biology. 4: 742-750. PMID 19031531 DOI: 10.1038/Nchembio.124  0.678
2008 Shen F, Kastrup CJ, Liu Y, Ismagilov RF. Threshold response of initiation of blood coagulation by tissue factor in patterned microfluidic capillaries is controlled by shear rate Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2035-2041. PMID 18703776 DOI: 10.1161/Atvbaha.108.173930  0.629
2008 Shen F, Kastrup CJ, Ismagilov RF. Using microfluidics to understand the effect of spatial distribution of tissue factor on blood coagulation Thrombosis Research. 122: S27-S30. PMID 18691495 DOI: 10.1016/S0049-3848(08)70015-X  0.665
2008 Runyon MK, Kastrup CJ, Johnson-Kerner BL, Van Ha TG, Ismagilov RF. Effects of shear rate on propagation of blood clotting determined using microfluidics and numerical simulations Journal of the American Chemical Society. 130: 3458-3464. PMID 18302373 DOI: 10.1021/Ja076301R  0.596
2008 Kastrup CJ, Runyon MK, Lucchetta EM, Price JM, Ismagilov RF. Using chemistry and microfluidics to understand the spatial dynamics of complex biological networks Accounts of Chemical Research. 41: 549-558. PMID 18217723 DOI: 10.1021/Ar700174G  0.61
2007 Kastrup CJ, Shen F, Runyon MK, Ismagilov RF. Characterization of the threshold response of initiation of blood clotting to stimulus patch size Biophysical Journal. 93: 2969-2977. PMID 17586576 DOI: 10.1529/Biophysj.107.109009  0.684
2007 Runyon MK, Johnson-Kerner BL, Kastrup CJ, Van Ha TG, Ismagilov RF. Propagation of blood clotting in the complex biochemical network of hemostasis is described by a simple mechanism Journal of the American Chemical Society. 129: 7014-7015. PMID 17497790 DOI: 10.1021/Ja072602P  0.616
2007 Kastrup CJ, Shen F, Ismagilov RF. Response to shape emerges in a complex biochemical network and its simple chemical analogue Angewandte Chemie - International Edition. 46: 3660-3662. PMID 17407119 DOI: 10.1002/Anie.200604995  0.583
2006 Kastrup CJ, Runyon MK, Shen F, Ismagilov RF. Modular chemical mechanism predicts spatiotemporal dynamics of initiation in the complex network of hemostasis Proceedings of the National Academy of Sciences of the United States of America. 103: 15747-15752. PMID 17043240 DOI: 10.1073/Pnas.0605560103  0.687
Low-probability matches (unlikely to be authored by this person)
2016 Chan KY, Zhao C, Siren EM, Chan JC, Boschman J, Kastrup CJ. Adhesion of blood clots can be enhanced when copolymerized with a macromer that is cross-linked by coagulation factor XIIIa. Biomacromolecules. PMID 27140446 DOI: 10.1021/acs.biomac.6b00481  0.299
2020 Ponczek MB, Shamanaev A, LaPlace A, Dickeson SK, Srivastava P, Sun MF, Gruber A, Kastrup C, Emsley J, Gailani D. The evolution of factor XI and the kallikrein-kinin system. Blood Advances. 4: 6135-6147. PMID 33351111 DOI: 10.1182/bloodadvances.2020002456  0.275
2022 Bao G, Gao Q, Cau M, Ali-Mohamad N, Strong M, Jiang S, Yang Z, Valiei A, Ma Z, Amabili M, Gao ZH, Mongeau L, Kastrup C, Li J. Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage. Nature Communications. 13: 5035. PMID 36028516 DOI: 10.1038/s41467-022-32803-1  0.238
2019 Hur WS, Warner H, Machan L, Kastrup CJ. Coagulation factor XIII-A and activated XIII-A decrease in some deep vein thrombosis patients following catheter-directed thrombolysis. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. PMID 30762590 DOI: 10.1097/MBC.0000000000000797  0.224
2018 Hur WS, Mazinani N, Lu XJD, Yefet LS, Byrnes JR, Ho L, Yeon JH, Filipenko S, Wolberg AS, Jefferies WA, Kastrup CJ. Coagulation factor XIIIa crosslinks amyloid b into dimers and oligomers and to blood proteins. The Journal of Biological Chemistry. PMID 30409906 DOI: 10.1074/Jbc.Ra118.005352  0.22
2015 Baylis JR, Yeon JH, Thomson MH, Kazerooni A, Wang X, St John AE, Lim EB, Chien D, Lee A, Zhang JQ, Piret JM, Machan LS, Burke TF, White NJ, Kastrup CJ. Self-propelled particles that transport cargo through flowing blood and halt hemorrhage. Science Advances. 1: e1500379. PMID 26601282 DOI: 10.1126/Sciadv.1500379  0.217
2020 Juang LJ, Mazinani N, Novakowski SK, Prowse ENP, Haulena M, Gailani D, Lavkulich LM, Kastrup CJ. Coagulation factor XII contributes to hemostasis when activated by soil in wounds. Blood Advances. 4: 1737-1745. PMID 32339233 DOI: 10.1182/Bloodadvances.2019000425  0.214
2024 Cau MF, Ferraresso F, Seadler M, Badior K, Zhang Y, Ketelboeter LM, Rodriguez GG, Chen T, Ferraresso M, Wietrzny A, Robertson M, Haugen A, Cullis PR, de Moya M, Dyer M, ... Kastrup CJ, et al. siRNA-mediated reduction of a circulating protein in swine using lipid nanoparticles. Molecular Therapy. Methods & Clinical Development. 32: 101258. PMID 38779336 DOI: 10.1016/j.omtm.2024.101258  0.212
2021 Leung J, Cau MF, Kastrup CJ. Emerging gene therapies for enhancing the hemostatic potential of platelets. Transfusion. 61: S275-S285. PMID 34269451 DOI: 10.1111/trf.16519  0.208
2021 Juang LJ, Hur WS, Silva LM, Strilchuk AW, Francisco B, Leung J, Robertson MK, Groeneveld DJ, La Prairie B, Chun EM, Cap AP, Luyendyk JP, Palumbo JS, Cullis PR, Bugge TH, ... ... Kastrup CJ, et al. Suppression of fibrin(ogen)-driven pathologies through controlled knockdown by lipid nanoparticle delivery of siRNA. Blood. PMID 34958662 DOI: 10.1182/blood.2021014559  0.206
2020 Strilchuk AW, Meixner SC, Leung J, Safikhan N, Kulkarni JA, Russell HM, van der Meel R, Sutherland MR, Owens Iii AP, Palumbo J, Conway EM, Pryzdial EL, Cullis P, Kastrup CJ. Sustained Depletion of FXIII-A by Inducing Acquired FXIII-B Deficiency. Blood. PMID 32678423 DOI: 10.1182/Blood.2020004976  0.205
2023 Leung J, Strong C, Badior KE, Robertson M, Wu X, Meledeo MA, Kang E, Paul M, Sato Y, Harashima H, Cap AP, Devine DV, Jan E, Cullis PR, Kastrup CJ. Genetically engineered transfusable platelets using mRNA lipid nanoparticles. Science Advances. 9: eadi0508. PMID 38039367 DOI: 10.1126/sciadv.adi0508  0.199
2022 Hernandez GE, Ma F, Martinez G, Firozabadi NB, Salvador J, Juang LJ, Leung J, Zhao P, López DA, Ardehali R, Beaudin AE, Kastrup CJ, Pellegrini M, Flick MJ, Iruela-Arispe ML. Aortic intimal resident macrophages are essential for maintenance of the non-thrombogenic intravascular state. Nature Cardiovascular Research. 1: 67-84. PMID 35599984 DOI: 10.1038/s44161-021-00006-4  0.197
2012 Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, et al. Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. Proceedings of the National Academy of Sciences of the United States of America. 109: 21444-9. PMID 23236189 DOI: 10.1073/Pnas.1217972110  0.196
2016 Baylis JR, Chan KY, Kastrup CJ. Halting hemorrhage with self-propelling particles and local drug delivery. Thrombosis Research. 141: S36-S39. PMID 27207421 DOI: 10.1016/S0049-3848(16)30362-0  0.191
2020 Hur WS, Juang LJ, Mazinani N, Munro L, Jefferies WA, Kastrup CJ. Post-Translational Modifications of Platelet-Derived Amyloid Precursor Protein by Coagulation Factor XIII-A. Biochemistry. PMID 33161719 DOI: 10.1021/acs.biochem.0c00450  0.178
2014 Kretschmer M, Reiner E, Hu G, Tam N, Oliveira DL, Caza M, Yeon JH, Kim J, Kastrup CJ, Jung WH, Kronstad JW. Defects in phosphate acquisition and storage influence virulence of Cryptococcus neoformans. Infection and Immunity. 82: 2697-712. PMID 24711572 DOI: 10.1128/IAI.01607-14  0.167
2012 Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG. Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics. Biomaterials. 33: 5004-12. PMID 22494889 DOI: 10.1016/J.Biomaterials.2012.03.065  0.158
2020 Chan KYT, Yong ASM, Wang X, Ringgold KM, St John AE, Baylis JR, White NJ, Kastrup CJ. The adhesion of clots in wounds contributes to hemostasis and can be enhanced by coagulation factor XIII. Scientific Reports. 10: 20116. PMID 33208779 DOI: 10.1038/s41598-020-76782-z  0.153
2012 Schroeder A, Goldberg MS, Kastrup C, Wang Y, Jiang S, Joseph BJ, Levins CG, Kannan ST, Langer R, Anderson DG. Remotely activated protein-producing nanoparticles. Nano Letters. 12: 2685-9. PMID 22432731 DOI: 10.1021/Nl2036047  0.143
2021 Silva LM, Doyle AD, Greenwell-Wild T, Dutzan N, Tran CL, Abusleme L, Juang LJ, Leung J, Chun EM, Lum AG, Agler CS, Zuazo CE, Sibree M, Jani P, Kram V, ... ... Kastrup CJ, et al. Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier. Science (New York, N.Y.). 374: eabl5450. PMID 34941394 DOI: 10.1126/science.abl5450  0.137
2016 Baylis JR, St John AE, Wang X, Lim EB, Statz ML, Chien D, Simonson E, Stern SA, Liggins RT, White NJ, Kastrup CJ. Self-Propelled Dressings Containing Thrombin and Tranexamic Acid Improve Short-Term Survival in a Swine Model of Lethal Junctional Hemorrhage. Shock (Augusta, Ga.). PMID 27206277 DOI: 10.1097/SHK.0000000000000646  0.136
2015 Chan V, Novakowski SK, Law S, Klein-Bosgoed C, Kastrup CJ. Controlled Transcription of Exogenous mRNA in Platelets Using Protocells. Angewandte Chemie (International Ed. in English). 54: 13590-3. PMID 26368852 DOI: 10.1002/anie.201506500  0.134
2021 Hur WS, Paul DS, Bouck EG, Negron O, Mwiza JMN, Poole LG, Cline-Fedewa HM, Clark EG, Juang LJ, Leung J, Kastrup CJ, Ugarova TP, Wolberg AS, Luyendyk JP, Bergmeier W, et al. Hypofibrinogenemia with preserved hemostasis and protection from thrombosis in mice with a Fga truncation mutation. Blood. PMID 34905618 DOI: 10.1182/blood.2021012537  0.131
2024 Ferraresso F, Leung J, Kastrup CJ. RNA Therapeutics to Control Fibrinolysis: Review on Applications in Biology and Medicine. Journal of Thrombosis and Haemostasis : Jth. PMID 38663489 DOI: 10.1016/j.jtha.2024.04.006  0.12
2020 Lee J, Lee HA, Shin M, Juang LJ, Kastrup CJ, Go GM, Lee H. Diatom Frustule Silica Exhibits Superhydrophilicity and Superhemophilicity. Acs Nano. PMID 32207961 DOI: 10.1021/acsnano.0c00621  0.118
2012 Chen D, Love KT, Chen Y, Eltoukhy AA, Kastrup C, Sahay G, Jeon A, Dong Y, Whitehead KA, Anderson DG. Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation. Journal of the American Chemical Society. 134: 6948-51. PMID 22475086 DOI: 10.1021/Ja301621Z  0.118
2010 Cheng H, Kastrup CJ, Ramanathan R, Siegwart DJ, Ma M, Bogatyrev SR, Xu Q, Whitehead KA, Langer R, Anderson DG. Nanoparticulate cellular patches for cell-mediated tumoritropic delivery. Acs Nano. 4: 625-31. PMID 20121215 DOI: 10.1021/Nn901319Y  0.113
2022 Cau MF, Ali-Mohamad N, Yeh H, Baylis JR, Peng H, Gao HZ, Rezende-Neto J, Grecov D, White NJ, Tenn C, Semple HA, Beckett A, Kastrup CJ. Percutaneous delivery of self-propelling thrombin-containing powder increases survival from non-compressible truncal hemorrhage in a swine model of coagulopathy and hypothermia. The Journal of Trauma and Acute Care Surgery. PMID 35545803 DOI: 10.1097/TA.0000000000003670  0.113
2022 Jiang SX, Chahal D, Ali-Mohamad N, Kastrup C, Donnellan F. Hemostatic powders for gastrointestinal bleeding: a review of old, new, and emerging agents in a rapidly advancing field. Endoscopy International Open. 10: E1136-E1146. PMID 36238531 DOI: 10.1055/a-1836-8962  0.113
2024 Strilchuk AW, Hur WS, Batty P, Sang Y, Abrahams SR, Yong ASM, Leung J, Silva LM, Schroeder JA, Nesbitt K, de Laat B, Moutsopoulos NM, Bugge TH, Shi Q, Cullis PR, ... ... Kastrup CJ, et al. Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A. Science Translational Medicine. 16: eadh0027. PMID 38381848 DOI: 10.1126/scitranslmed.adh0027  0.108
2023 Ali-Mohamad N, Cau MF, Zenova V, Baylis JR, Beckett A, McFadden A, Donnellan F, Kastrup CJ. Self-propelling thrombin powder enables hemostasis with no observable rebleeding or thrombosis over three days in a porcine model of upper gastrointestinal bleeding. Gastrointestinal Endoscopy. PMID 37061138 DOI: 10.1016/j.gie.2023.04.007  0.107
2023 Ali-Mohamad N, Cau MF, Wang X, Khavari A, Ringgold K, Naveed A, Sherwood C, Peng N, Zhang Gao H, Zhang Y, Semple H, Peng H, Tenn C, Baylis JR, Beckett A, ... ... Kastrup CJ, et al. Ruggedized Self-Propelling Hemostatic Gauze Delivers Low Dose of Thrombin and Systemic Tranexamic Acid and Achieves High Survival in Swine With Junctional Hemorrhage. Military Medicine. 188: 280-287. PMID 37948225 DOI: 10.1093/milmed/usad110  0.101
2021 Ali-Mohamad N, Cau M, Baylis J, Zenova V, Semple H, Beckett A, McFadden A, Donnellan F, Kastrup C. Severe upper gastrointestinal bleeding is halted by endoscopically delivered self-propelling thrombin powder: A porcine pilot study. Endoscopy International Open. 9: E693-E698. PMID 33937509 DOI: 10.1055/a-1374-5839  0.098
2019 Baylis JR, Lee MM, St John AE, Wang X, Simonson E, Cau M, Kazerooni A, Gusti V, Statz ML, Yoon JSJ, Liggins RT, White NJ, Kastrup CJ. Topical tranexamic acid inhibits fibrinolysis more effectively when formulated with self-propelling particles. Journal of Thrombosis and Haemostasis : Jth. PMID 31145837 DOI: 10.1111/jth.14526  0.095
2022 Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Molecular Pharmaceutics. PMID 35642083 DOI: 10.1021/acs.molpharmaceut.2c00033  0.084
2021 Cau MF, Strilchuk AW, Kastrup CJ. Nanomedicines for hemorrhage control. Journal of Thrombosis and Haemostasis : Jth. 19: 887-891. PMID 33694243 DOI: 10.1111/jth.15211  0.084
2022 Ali-Mohamad N, Cau MF, Baylis JR, Semple H, Kastrup CJ, Beckett A. Videoconferencing for Large Animal Trauma Experiments During COVID-19: A Cross-Continent Experience. Military Medicine. PMID 35231116 DOI: 10.1093/milmed/usac032  0.078
2022 Cau MF, Ali-Mohamad N, Baylis JR, Zenova V, Khavari A, Peng N, McFadden A, Donnellan F, Owen DR, Schaeffer DF, Nagaswami C, Litvinov RI, Weisel JW, Rezende-Neto J, Semple HA, ... ... Kastrup CJ, et al. Percutaneous delivery of self-propelling hemostatic powder for managing non-compressible abdominal hemorrhage: a proof-of-concept study in swine. Injury. PMID 35067343 DOI: 10.1016/j.injury.2022.01.024  0.064
2022 Hur WS, King KC, Patel YN, Nguyen YV, Wei Z, Yang Y, Juang LJ, Leung J, Kastrup CJ, Wolberg AS, Luyendyk JP, Flick MJ. Elimination of fibrin polymer formation or crosslinking, but not fibrinogen deficiency, is protective against diet-induced obesity and associated pathologies. Journal of Thrombosis and Haemostasis : Jth. PMID 36111375 DOI: 10.1111/jth.15877  0.063
2020 Mazinani N, Strilchuk AW, Baylis JR, Hur WS, Jefferies WA, Kastrup CJ. Bleeding is increased in amyloid precursor protein knockout mouse. Research and Practice in Thrombosis and Haemostasis. 4: 823-828. PMID 32685890 DOI: 10.1002/rth2.12375  0.062
2003 Kastrup CJ, Oldfield SP, Rzepa HS. The aromaticity and Möbius characteristics of carbeno[8]heteroannulenes and triplet state annulenes. Chemical Communications (Cambridge, England). 642-3. PMID 12120163 DOI: 10.1039/b110626k  0.024
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