| Year |
Citation |
Score |
| 2023 |
Zhu W, Butrin A, Melani RD, Doubleday PF, Ferreira GM, Tavares MT, Habeeb Mohammad TS, Beaupre BA, Kelleher NL, Moran GR, Liu D, Silverman RB. Correction to "Rational Design, Synthesis, and Mechanism of (3,4)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase". Journal of the American Chemical Society. 145: 9895-9896. PMID 37075548 DOI: 10.1021/jacs.3c03364 |
0.504 |
|
| 2023 |
Shen S, Butrin A, Beaupre BA, Ferreira GM, Doubleday PF, Grass DH, Zhu W, Kelleher NL, Moran GR, Liu D, Silverman RB. Structural and Mechanistic Basis for the Inactivation of Human Ornithine Aminotransferase by (3,4)-3-Amino-4-fluorocyclopentenecarboxylic Acid. Molecules (Basel, Switzerland). 28. PMID 36770800 DOI: 10.3390/molecules28031133 |
0.627 |
|
| 2022 |
Butrin A, Butrin A, Wawrzak Z, Moran G, Liu D. Determination of the pH-Dependence, Substrate Specificity and Turnovers of Alternative Substrates for Human Ornithine Aminotransferase. The Journal of Biological Chemistry. 101969. PMID 35460691 DOI: 10.1016/j.jbc.2022.101969 |
0.541 |
|
| 2022 |
Zhu W, Butrin A, Melani RD, Doubleday PF, Ferreira GM, Tavares MT, Habeeb Mohammad TS, Beaupre BA, Kelleher NL, Moran GR, Liu D, Silverman RB. Rational Design, Synthesis, and Mechanism of (3,4)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase. Journal of the American Chemical Society. PMID 35293728 DOI: 10.1021/jacs.2c00924 |
0.682 |
|
| 2021 |
Shen S, Butrin A, Doubleday PF, Melani RD, Beaupre BA, Tavares MT, Ferreira GM, Kelleher NL, Moran GR, Liu D, Silverman RB. Turnover and Inactivation Mechanisms for ()-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. Journal of the American Chemical Society. PMID 34097381 DOI: 10.1021/jacs.1c02456 |
0.635 |
|
| 2021 |
Beaupre BA, Forouzesh DC, Butrin A, Liu D, Moran GR. Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase. Biochemistry. 60: 1764-1775. PMID 34032117 DOI: 10.1021/acs.biochem.1c00243 |
0.385 |
|
| 2021 |
Zhu W, Doubleday PF, Butrin A, Weerawarna PM, Melani RD, Catlin DS, Dwight TA, Liu D, Kelleher NL, Silverman RB. Remarkable and Unexpected Mechanism for ()-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase. Journal of the American Chemical Society. PMID 34014654 DOI: 10.1021/jacs.1c03572 |
0.595 |
|
| 2021 |
Forouzesh DC, Beaupre BA, Butrin A, Wawrzak Z, Liu D, Moran GR. The Interaction of Porcine Dihydropyrimidine Dehydrogenase with the Chemotherapy Sensitizer: 5-Ethynyluracil. Biochemistry. PMID 33755421 DOI: 10.1021/acs.biochem.1c00096 |
0.459 |
|
| 2020 |
Butrin A, Beaupre BA, Kadamandla N, Zhao P, Shen S, Silverman RB, Moran GR, Liu D. Structural and Kinetic Analyses Reveal the Dual Inhibition Modes of Ornithine Aminotransferase by (1,3)-3-Amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic Acid (BCF). Acs Chemical Biology. PMID 33316155 DOI: 10.1021/acschembio.0c00728 |
0.608 |
|
| 2020 |
Zhu W, Doubleday PF, Catlin DS, Weerawarna PM, Butrin A, Shen S, Wawrzak Z, Kelleher NL, Liu D, Silverman RB. A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid. Journal of the American Chemical Society. PMID 32114761 DOI: 10.1021/Jacs.0C00193 |
0.494 |
|
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