Xiwei Wu, Ph.D. - Publications

Affiliations: 
2002 Loma Linda University, Loma Linda, United States 
Area:
Cell Biology, Immunology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mohanty A, Nam A, Pozhitkov A, Yang L, Srivastava S, Nathan A, Wu X, Mambetsariev I, Nelson M, Subbalakshmi AR, Guo L, Nasser MW, Batra SK, Orban J, Jolly MK, et al. A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer. Iscience. 23: 101496. PMID 32947124 DOI: 10.1016/J.Isci.2020.101496  0.323
2020 Su R, Dong L, Li Y, Gao M, Han L, Wunderlich M, Deng X, Li H, Huang Y, Gao L, Li C, Zhao Z, Robinson S, Tan B, Qing Y, ... ... Wu X, et al. Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion. Cancer Cell. PMID 32531268 DOI: 10.1016/J.Ccell.2020.04.017  0.351
2020 Singh AK, Zhao B, Liu X, Wang X, Li H, Qin H, Wu X, Ma Y, Horne D, Yu X. Selective targeting of TET catalytic domain promotes somatic cell reprogramming. Proceedings of the National Academy of Sciences of the United States of America. PMID 32024762 DOI: 10.1073/Pnas.1910702117  0.338
2020 Mori H, Saeki K, Chang G, Wu X, Hsu P, Kanaya N, Somlo G, Chen S. Abstract P1-08-01: Estrogen-induced cell cycle arrest and apoptosis in aromatase inhibitor-resistant breast cancer: Insights from single cells analysis of a patient-derived xenograft model Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P1-08-01  0.334
2020 Mohanty A, Nam A, Pozhitkov A, Yang L, Nelson M, Wu X, Kulkarni P, Massarelli E, Salgia R. Abstract 2607: Integrin Beta4/Paxillin mediated chemoresistance in lung adenocarcinoma Cancer Research. 80: 2607-2607. DOI: 10.1158/1538-7445.Am2020-2607  0.384
2019 Buettner R, Morales C, Wu X, Sanchez JF, Li H, Melstrom LG, Rosen ST. Leflunomide Synergizes with Gemcitabine in Growth Inhibition of PC Cells and Impairs c-Myc Signaling through PIM Kinase Targeting. Molecular Therapy Oncolytics. 14: 149-158. PMID 31211245 DOI: 10.1016/J.Omto.2019.04.006  0.3
2019 Shen M, Dong C, Ruan X, Yan W, Cao M, Pizzo D, Wu X, Yang L, Liu L, Ren X, Wang SE. Chemotherapy-induced extracellular vesicle miRNAs promote breast cancer stemness by targeting ONECUT2. Cancer Research. PMID 31118200 DOI: 10.1158/0008-5472.Can-18-4055  0.369
2019 Huang H, Weng H, Zhou K, Wu T, Zhao BS, Sun M, Chen Z, Deng X, Xiao G, Auer F, Klemm L, Wu H, Zuo Z, Qin X, Dong Y, ... ... Wu X, et al. Histone H3 trimethylation at lysine 36 guides mA RNA modification co-transcriptionally. Nature. PMID 30867593 DOI: 10.1038/S41586-019-1016-7  0.313
2019 Kanaya N, Bernal L, Chang G, Yamamoto T, Nguyen D, Wang YZ, Park JS, Warden C, Wang J, Wu X, Synold T, Rakoff M, Neuhausen SL, Chen S. Molecular Mechanisms of Polybrominated Diphenyl Ethers (BDE-47, -100 and -153) in Human Breast Cancer Cells and Patient-Derived Xenografts. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 30796839 DOI: 10.1093/Toxsci/Kfz054  0.344
2019 Su R, Dong L, Li Y, Han L, Gao M, Wunderlich M, Deng X, Li H, Gao L, Li C, Robison S, Tan B, Qing Y, Qin X, Prince E, ... ... Wu X, et al. Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance Blood. 134: 233-233. DOI: 10.1182/Blood-2019-124535  0.337
2018 Yoon S, Wu X, Armstrong B, Habib N, Rossi JJ. An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma. Molecular Therapy. Nucleic Acids. 14: 131-141. PMID 30594071 DOI: 10.1016/J.Omtn.2018.11.012  0.358
2018 Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, et al. SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell. PMID 30146412 DOI: 10.1016/J.Stem.2018.07.018  0.331
2018 Geng A, Qiu R, Murai K, Liu J, Wu X, Zhang H, Farhoodi H, Duong N, Jiang M, Yee JK, Tsark W, Lu Q. KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. Nature Communications. 9: 2707. PMID 30006548 DOI: 10.1038/S41467-018-05152-1  0.307
2018 Petrossian K, Kanaya N, Lo C, Hsu PY, Nguyen D, Yang L, Yang L, Warden C, Wu X, Pillai R, Bernal L, Huang CS, Kruper L, Yuan Y, Somlo G, et al. ERα-mediated cell cycle progression is an important requisite for CDK4/6 inhibitor response in HR+ breast cancer. Oncotarget. 9: 27736-27751. PMID 29963233 DOI: 10.18632/Oncotarget.25552  0.339
2018 Chen SF, Liu Z, Chaurasiya S, Dellinger TH, Lu J, Wu X, Qin H, Wang J, Fong Y, Yuan YC. Identification of core aberrantly expressed microRNAs in serous ovarian carcinoma. Oncotarget. 9: 20451-20466. PMID 29755664 DOI: 10.18632/Oncotarget.24942  0.301
2018 Poroyko V, Mirzapoiazova T, Nam A, Mambetsariev I, Mambetsariev B, Wu X, Husain A, Vokes EE, Wheeler DL, Salgia R. Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients. Oncotarget. 9: 19793-19806. PMID 29731983 DOI: 10.18632/Oncotarget.24857  0.312
2018 Yan W, Wu X, Zhou W, Fong MY, Cao M, Liu J, Liu X, Chen CH, Fadare O, Pizzo DP, Wu J, Liu L, Liu X, Chin AR, Ren X, et al. Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells. Nature Cell Biology. PMID 29662176 DOI: 10.1038/S41556-018-0083-6  0.306
2018 Li S, Ali S, Duan X, Liu S, Du J, Liu C, Dai H, Zhou M, Zhou L, Yang L, Chu P, Li L, Bhatia R, Schones DE, Wu X, et al. JMJD1B Demethylates H4R3me2s and H3K9me2 to Facilitate Gene Expression for Development of Hematopoietic Stem and Progenitor Cells. Cell Reports. 23: 389-403. PMID 29641999 DOI: 10.1016/J.Celrep.2018.03.051  0.332
2018 Awasthi S, Tompkins J, Singhal J, Riggs AD, Yadav S, Wu X, Singh S, Warden C, Liu Z, Wang J, Slavin TP, Weitzel JN, Yuan YC, Awasthi M, Srivastava SK, et al. Rlip depletion prevents spontaneous neoplasia in TP53 null mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 29572430 DOI: 10.1073/Pnas.1719586115  0.358
2017 Das S, Senapati P, Chen Z, Reddy MA, Ganguly R, Lanting L, Mandi V, Bansal A, Leung A, Zhang S, Jia Y, Wu X, Schones DE, Natarajan R. Regulation of angiotensin II actions by enhancers and super-enhancers in vascular smooth muscle cells. Nature Communications. 8: 1467. PMID 29133788 DOI: 10.1038/S41467-017-01629-7  0.322
2017 Yang L, Liu J, Lu Q, Riggs AD, Wu X. SAIC: an iterative clustering approach for analysis of single cell RNA-seq data. Bmc Genomics. 18: 689. PMID 28984204 DOI: 10.1186/S12864-017-4019-5  0.315
2017 Liu J, Wu X, Zhang H, Pfeifer GP, Lu Q. Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development. Cell Reports. 20: 1307-1318. PMID 28793256 DOI: 10.1016/J.Celrep.2017.07.046  0.301
2017 Gu Y, Zhang J, Ma X, Kim BW, Wang H, Li J, Pan Y, Xu Y, Ding L, Yang L, Guo C, Wu X, Wu J, Wu K, Gan X, et al. Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma. Cancer Cell. 32: 115-128.e7. PMID 28697340 DOI: 10.1016/J.Ccell.2017.06.001  0.3
2017 Slavin TP, Neuhausen SL, Nehoray B, Niell-Swiller M, Solomon I, Rybak C, Blazer K, Adamson A, Yang K, Sand S, Guerrero-Llamas N, Castillo D, Herzog J, Wu X, Tao S, et al. The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes. Familial Cancer. PMID 28687971 DOI: 10.1007/S10689-017-0019-5  0.321
2017 Guan M, Wu X, Chu P, Chow WA. Fatty acid synthase reprograms the epigenome in uterine leiomyosarcomas. Plos One. 12: e0179692. PMID 28654693 DOI: 10.1371/Journal.Pone.0179692  0.358
2017 Hanley MP, Hahn MA, Li AX, Wu X, Lin J, Wang J, Choi AH, Ouyang Z, Fong Y, Pfeifer GP, Devers TJ, Rosenberg DW. Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia. Oncogene. PMID 28459462 DOI: 10.1038/Onc.2017.130  0.347
2017 Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, Wu X, Antony S, Wu Y, Melillo G, Meitzler JL, Haines DC, Butcher D, Roy K, Doroshow JH. NADPH Oxidase 1 Supports Proliferation of Colon Cancer Cells by Modulating Reactive Oxygen Species-Dependent Signal Transduction. The Journal of Biological Chemistry. PMID 28330872 DOI: 10.1074/Jbc.M116.768283  0.365
2017 Tew BY, Hong TB, Otto-Duessel M, Elix C, Castro E, He M, Wu X, Pal SK, Kalkum M, Jones JO. Vitamin K epoxide reductase regulation of androgen receptor activity. Oncotarget. PMID 28099154 DOI: 10.18632/Oncotarget.14639  0.724
2017 Buettner R, Morales CJ, Caserta E, Viola D, Palmer JM, Wu X, Vaidehi N, Li H, Synold T, Krishnan A, Pichiorri F, Rosenzweig M, Rosen ST. Leflunomide Inhibits c-Myc Signaling and Impairs Myeloma Cell Growth Blood. 130: 4426-4426. DOI: 10.1182/Blood.V130.Suppl_1.4426.4426  0.354
2016 Ding Y, Wu H, Warden C, Steele L, Liu X, Iterson MV, Wu X, Nelson R, Liu Z, Yuan YC, Neuhausen SL. Gene Expression Differences in Prostate Cancers between Young and Old Men. Plos Genetics. 12: e1006477. PMID 28027300 DOI: 10.1371/Journal.Pgen.1006477  0.332
2016 Tompkins JD, Jung M, Chen CY, Lin Z, Ye J, Godatha S, Lizhar E, Wu X, Hsu D, Couture LA, Riggs AD. Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation "Memories". Ebiomedicine. 4: 74-85. PMID 26981572 DOI: 10.1016/J.Ebiom.2016.01.021  0.323
2016 Cui Q, Yang S, Ye P, Tian E, Sun G, Zhou J, Sun G, Liu X, Chen C, Murai K, Zhao C, Azizian KT, Yang L, Warden C, Wu X, et al. Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis. Nature Communications. 7: 10637. PMID 26838672 DOI: 10.1038/Ncomms10637  0.332
2016 Chin AR, Fong MY, Somlo G, Wu J, Swiderski P, Wu X, Wang SE. Cross-kingdom inhibition of breast cancer growth by plant miR159. Cell Research. PMID 26794868 DOI: 10.1038/Cr.2016.13  0.317
2016 Wu H, Wu X, Jin JM, Li AX, Tong T, Ma D, Nelson RA, Li Y, Pal SK, Kim YS, Haberman K, Zhai J, Lau CS, Guo C, Wu JJ, et al. An optimized microRNA signature algorithm to predict clear cell renal cell carcinoma metastasis: A 265-case validation study using paraffin specimens. Journal of Clinical Oncology. 34: 612-612. DOI: 10.1200/Jco.2016.34.2_Suppl.612  0.319
2016 Yuan Y, Wu X, Yost S, Wang J, Yang L, Goldstein L, Liu Z, Yuan Y. A Retrospective Pilot Study of Longitudinal Molecular Discordance of Primary versus Recurrent Triple Negative Breast Cancer (TNBC). Journal of Clinical Oncology. 34: e12558-e12558. DOI: 10.1200/Jco.2016.34.15_Suppl.E12558  0.319
2016 Qi J, Cook GJ, Zhang B, Hua W, Qi C, Carnahan E, Marom A, Nguyen LXT, Lu Y, Branciamore S, Wu H, Yuan Y, Wu X, Li L, Stein AS, et al. Time Sequential Transcriptome Analysis Identifies Mir-126 As an Early Biomarker for Inv(16) Acute Myeloid Leukemia (AML) Disease Progression Blood. 128: 773-773. DOI: 10.1182/Blood.V128.22.773.773  0.301
2016 Querfeld C, Wu X, Sanchez JF, Palmer JM, Motevalli A, Zain J, Rosen ST. The miRNA Profile of Cutaneous T Cell Lymphoma Correlates with the Dysfunctional Immunophenotype of the Disease Blood. 128: 4132-4132. DOI: 10.1182/Blood.V128.22.4132.4132  0.305
2016 Zhang XH, Ngo VN, Sandoval N, Cui Q, Shi Y, Zain JM, Querfeld C, Guo C, Wu X, Rosen ST. Role of p38γ - NFATc4 - IL17A Pathway As a Potential Therapeutic Target in Cutaneous T Cell Lymphoma Blood. 128: 2725-2725. DOI: 10.1182/Blood.V128.22.2725.2725  0.399
2016 Zhang K, Wang J, Wu X, Reno TA, Tong TR, Kim J, Raz D. Abstract 4523: Decreased H2B monoubiquitination is associated with enhanced proliferation and resistance to apoptosis in human lung cancer Cancer Research. 76: 4523-4523. DOI: 10.1158/1538-7445.Am2016-4523  0.372
2015 Jin SG, Xiong W, Wu X, Yang L, Pfeifer GP. The DNA methylation landscape of human melanoma. Genomics. PMID 26384656 DOI: 10.1016/J.Ygeno.2015.09.004  0.322
2015 Wang C, McKeithan TW, Gong Q, Zhang W, Bouska A, Rosenwald A, Gascoyne RD, Wu X, Wang J, Muhammad Z, Jiang B, Rohr J, Cannon A, Steidl C, Fu K, et al. IDH2R172 mutations define a unique subgroup of patients with angioimmunoblastic T-cell lymphoma. Blood. PMID 26268241 DOI: 10.1182/Blood-2015-05-644591  0.342
2015 Wang J, Zhang K, Wang J, Wu X, Liu X, Li B, Zhu Y, Yu Y, Cheng Q, Hu Z, Guo C, Hu S, Mu B, Tsai CH, Li J, et al. Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma. Oncotarget. PMID 26056085 DOI: 10.18632/Oncotarget.4305  0.344
2015 Li Y, Wu X, Gao H, Jin JM, Li AX, Kim YS, Pal SK, Nelson RA, Lau CM, Guo C, Mu B, Wang J, Wang F, Wang J, Zhao Y, et al. PIWI-interacting RNAs are dysregulated in renal cell carcinoma and associated with tumor metastasis and cancer specific survival. Molecular Medicine (Cambridge, Mass.). PMID 25998508 DOI: 10.2119/Molmed.2014.00203  0.35
2015 Chen B, Chen X, Wu X, Wang X, Wang Y, Lin TY, Kurata J, Wu J, Vonderfecht S, Sun G, Huang H, Yee JK, Hu J, Lin RJ. Disruption of microRNA-21 by TALEN leads to diminished cell transformation and increased expression of cell-environment interaction genes. Cancer Letters. 356: 506-16. PMID 25304376 DOI: 10.1016/J.Canlet.2014.09.034  0.315
2015 Pal SK, He M, Tong T, Wu H, Liu X, Lau C, Wang JH, Warden C, Wu X, Signoretti S, Choueiri TK, Karam JA, Jones JO. RNA-seq reveals aurora kinase-driven mTOR pathway activation in patients with sarcomatoid metastatic renal cell carcinoma. Molecular Cancer Research : McR. 13: 130-7. PMID 25183163 DOI: 10.1158/1541-7786.Mcr-14-0352  0.347
2015 Aboody K, Li Z, Oganesyan D, Mooney R, Christensen M, Shahmanyan D, D'Apuzzo M, Aramburo S, Lu Y, Perrigue P, Najbauer J, Wu X, Gutova M. STEM-10L-myc EXPRESSION PROMOTES HUMAN NEURAL STEM CELL MULTIPOTENCY Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov234.10  0.348
2014 Wang Z, Liu Z, Wu X, Chu S, Wang J, Yuan H, Roth M, Yuan YC, Bhatia R, Chen W. ATRA-induced cellular differentiation and CD38 expression inhibits acquisition of BCR-ABL mutations for CML acquired resistance. Plos Genetics. 10: e1004414. PMID 24967705 DOI: 10.1371/Journal.Pgen.1004414  0.326
2014 Hahn MA, Li AX, Wu X, Yang R, Drew DA, Rosenberg DW, Pfeifer GP. Loss of the polycomb mark from bivalent promoters leads to activation of cancer-promoting genes in colorectal tumors. Cancer Research. 74: 3617-29. PMID 24786786 DOI: 10.1158/0008-5472.Can-13-3147  0.378
2014 Zhou W, Fong MY, Min Y, Somlo G, Liu L, Palomares MR, Yu Y, Chow A, O'Connor ST, Chin AR, Yen Y, Wang Y, Marcusson EG, Chu P, Wu J, ... Wu X, et al. Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis. Cancer Cell. 25: 501-15. PMID 24735924 DOI: 10.1016/J.Ccr.2014.03.007  0.31
2014 Li J, Yang L, Gaur S, Zhang K, Wu X, Yuan YC, Li H, Hu S, Weng Y, Yen Y. Mutants TP53 p.R273H and p.R273C but not p.R273G enhance cancer cell malignancy. Human Mutation. 35: 575-84. PMID 24677579 DOI: 10.1002/Humu.22528  0.322
2014 Dery KJ, Kujawski M, Grunert D, Wu X, Ngyuen T, Cheung C, Yim JH, Shively JE. IRF-1 regulates alternative mRNA splicing of carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in breast epithelial cells generating an immunoreceptor tyrosine-based inhibition motif (ITIM) containing isoform. Molecular Cancer. 13: 64. PMID 24650050 DOI: 10.1186/1476-4598-13-64  0.323
2014 Zhang K, Gao H, Wu X, Wang J, Zhou W, Sun G, Wang J, Wang Y, Mu B, Kim C, Chu P, Ho DM, Ann DK, Wong TT, Yen Y. Frequent overexpression of HMGA2 in human atypical teratoid/rhabdoid tumor and its correlation with let-7a3/let-7b miRNA. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1179-89. PMID 24423609 DOI: 10.1158/1078-0432.Ccr-13-1452  0.308
2014 Tran DA, Bai AY, Singh P, Wu X, Szabó PE. Characterization of the imprinting signature of mouse embryo fibroblasts by RNA deep sequencing. Nucleic Acids Research. 42: 1772-83. PMID 24217910 DOI: 10.1093/Nar/Gkt1042  0.31
2014 Pal SK, Tong T, He M, Wu H, Liu X, Nelson RA, Wu X, Signoretti S, Choueiri TK, Jones J. Deep sequencing of sarcomatoid renal cell carcinoma (sRCC) and identification of aurora kinases and mTOR as potential therapeutic targets. Journal of Clinical Oncology. 32: 411-411. DOI: 10.1200/Jco.2014.32.4_Suppl.411  0.327
2013 Lahtz C, Kim SI, Bates SE, Li AX, Wu X, Pfeifer GP. UVB irradiation does not directly induce detectable changes of DNA methylation in human keratinocytes. F1000research. 2: 45. PMID 24555035 DOI: 10.12688/F1000Research.2-45.V1  0.319
2013 Hu Z, Wang J, Yao T, Hong RL, Zhang K, Gao H, Wu X, Li J, Bai C, Yen Y. Identification of novel mutations of TP53, ALK and RET gene in metastatic thymic squamous cell carcinoma and its therapeutic implication. Lung Cancer (Amsterdam, Netherlands). 81: 27-31. PMID 23639785 DOI: 10.1016/J.Lungcan.2013.04.006  0.335
2013 Hahn MA, Qiu R, Wu X, Li AX, Zhang H, Wang J, Jui J, Jin SG, Jiang Y, Pfeifer GP, Lu Q. Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Reports. 3: 291-300. PMID 23403289 DOI: 10.1016/J.Celrep.2013.01.011  0.302
2013 Zhang K, Chu K, Wu X, Gao H, Wang J, Yuan YC, Loera S, Ho K, Wang Y, Chow W, Un F, Chu P, Yen Y. Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma. Cancer Research. 73: 1298-307. PMID 23393200 DOI: 10.1158/0008-5472.Can-12-2086  0.326
2013 Miao F, Chen Z, Zhang L, Wang J, Gao H, Wu X, Natarajan R. RNA-sequencing analysis of high glucose-treated monocytes reveals novel transcriptome signatures and associated epigenetic profiles. Physiological Genomics. 45: 287-99. PMID 23386205 DOI: 10.1152/Physiolgenomics.00001.2013  0.314
2013 Doroshow JH, Gaur S, Markel S, Lu J, van Balgooy J, Synold TW, Xi B, Wu X, Juhasz A. Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts. Free Radical Biology & Medicine. 57: 162-75. PMID 23314043 DOI: 10.1016/J.Freeradbiomed.2013.01.002  0.357
2013 Hahn MA, Li AX, Wu X, Rosenberg DW, Pfeifer GP. Abstract B03: Loss of the Polycomb mark at bivalent promoters leads to activation of intestinal stem cell genes in colorectal cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-B03  0.375
2013 Li Y, Wu X, Gao H, Jin J, Pal S, Li A, Guo C, Nelson R, Wang J, Kim Y, Wang F, Wang J, Chen W, Wang S, Rossi J, et al. Abstract LB-247: 5′-tRFHis-GTG, a novel tRNA-derived novel miRNA-like small non-coding RNA, aberrantly expressed in metastatic renal cell carcinoma by promoting tumor cell proliferation, migration and invasion. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-247  0.366
2012 Chen Z, Gao H, Mu B, Wang J, Wu X, Qin H, Li W, Garcia-Aguilar J. Using deep sequencing of formalin-fixed paraffin embedded (FFPE) rectal cancer biopsy tissue to analyze miRNA expression in patients with rectal cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 487. PMID 27982940 DOI: 10.1200/Jco.2012.30.4_Suppl.487  0.319
2012 Lahtz C, Bates SE, Jiang Y, Li AX, Wu X, Hahn MA, Pfeifer GP. Gamma irradiation does not induce detectable changes in DNA methylation directly following exposure of human cells. Plos One. 7: e44858. PMID 23024770 DOI: 10.1371/Journal.Pone.0044858  0.311
2012 Tompkins JD, Hall C, Chen VC, Li AX, Wu X, Hsu D, Couture LA, Riggs AD. Epigenetic stability, adaptability, and reversibility in human embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 12544-9. PMID 22802633 DOI: 10.1073/Pnas.1209620109  0.32
2012 Wu X, Weng L, Li X, Guo C, Pal SK, Jin JM, Li Y, Nelson RA, Mu B, Onami SH, Wu JJ, Ruel NH, Wilczynski SP, Gao H, Covarrubias M, et al. Identification of a 4-microRNA signature for clear cell renal cell carcinoma metastasis and prognosis. Plos One. 7: e35661. PMID 22623952 DOI: 10.1371/Journal.Pone.0035661  0.317
2012 Zheng L, Dai H, Zhou M, Li X, Liu C, Guo Z, Wu X, Wu J, Wang C, Zhong J, Huang Q, Garcia-Aguilar J, Pfeifer GP, Shen B. Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression. Nature Communications. 3: 815. PMID 22569363 DOI: 10.1038/Ncomms1825  0.316
2012 Lang MF, Yang S, Zhao C, Sun G, Murai K, Wu X, Wang J, Gao H, Brown CE, Liu X, Zhou J, Peng L, Rossi JJ, Shi Y. Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells. Plos One. 7: e36248. PMID 22558405 DOI: 10.1371/Journal.Pone.0036248  0.324
2012 Tsuyada A, Chow A, Wu J, Somlo G, Chu P, Loera S, Luu T, Li AX, Wu X, Ye W, Chen S, Zhou W, Yu Y, Wang YZ, Ren X, et al. CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Research. 72: 2768-79. PMID 22472119 DOI: 10.1158/0008-5472.Can-11-3567  0.347
2012 Wu X, Somlo G, Yu Y, Palomares MR, Li AX, Zhou W, Chow A, Yen Y, Rossi JJ, Gao H, Wang J, Yuan YC, Frankel P, Li S, Ashing-Giwa KT, et al. De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer. Journal of Translational Medicine. 10: 42. PMID 22400902 DOI: 10.1186/1479-5876-10-42  0.302
2012 Wu X, Somlo G, Palomares M, Yen Y, Rossi J, Gao H, Wang SE. Abstract A9: De novo sequencing of circulating microRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer Cancer Research. 72: A9-A9. DOI: 10.1158/1538-7445.Nonrna12-A9  0.318
2012 Zhang K, Kim C, Wu X, Wang Y, Loera S, Shibata S, Yen Y. Abstract 5583: Decrease in expression of Gadd45 is associated with gemcitabine and hydroxyurea resistance in human head and neck squamous-cell carcinoma Cancer Research. 72: 5583-5583. DOI: 10.1158/1538-7445.Am2012-5583  0.336
2012 Chen Z, Mu B, Qin H, Wang J, Wu X, Gao H, li W, Garcia-Aguilar J. Abstract 3159: Differential miRNA expression profiling of rectal and colon cancers using deep sequencing Cancer Research. 72: 3159-3159. DOI: 10.1158/1538-7445.Am2012-3159  0.345
2011 Wang J, Zhang H, Young AG, Qiu R, Argalian S, Li X, Wu X, Lemke G, Lu Q. Transcriptome analysis of neural progenitor cells by a genetic dual reporter strategy. Stem Cells (Dayton, Ohio). 29: 1589-600. PMID 21805534 DOI: 10.1002/Stem.699  0.308
2011 Gaur S, Chen L, Yang L, Wu X, Un F, Yen Y. Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors. Cancer Letters. 311: 20-8. PMID 21764510 DOI: 10.1016/J.Canlet.2011.06.005  0.333
2011 Yang L, Wu X, Wang Y, Zhang K, Wu J, Yuan YC, Deng X, Chen L, Kim CC, Lau S, Somlo G, Yen Y. FZD7 has a critical role in cell proliferation in triple negative breast cancer. Oncogene. 30: 4437-46. PMID 21532620 DOI: 10.1038/Onc.2011.145  0.354
2011 Hahn MA, Wu X, Li AX, Hahn T, Pfeifer GP. Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks. Plos One. 6: e18844. PMID 21526191 DOI: 10.1371/Journal.Pone.0018844  0.31
2011 Zheng L, Dai H, Hegde ML, Zhou M, Guo Z, Wu X, Wu J, Su L, Zhong X, Mitra S, Huang Q, Kernstine KH, Pfeifer GP, Shen B. Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer. Cell Research. 21: 1052-67. PMID 21383776 DOI: 10.1038/Cr.2011.35  0.326
2011 Jin SG, Wu X, Li AX, Pfeifer GP. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Research. 39: 5015-24. PMID 21378125 DOI: 10.1093/Nar/Gkr120  0.313
2011 Qin H, Wang Z, Du W, Lee WH, Wu X, Riggs AD, Liu CP. Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 108: 2016-21. PMID 21245333 DOI: 10.1073/Pnas.1019082108  0.328
2011 Guo R, Chang L, Liu Z, Li AX, Huang Q, Ann DK, Wang HC, Lin CW, Wu X, Yuan YC, Yen Y. Canonical nuclear factor κB pathway links tumorigenesis of synchronous mantle-cell lymphoma, clear-cell renal-cell carcinoma, and GI stromal tumor. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e257-61. PMID 21220613 DOI: 10.1200/Jco.2010.32.1802  0.302
2011 Zhang K, Wu J, Wu X, Wang X, Wang Y, Zhou N, Kuo ML, Liu X, Zhou B, Chang L, Ann D, Yen Y. p53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest. Molecular Cancer Therapeutics. 10: 269-78. PMID 21216934 DOI: 10.1158/1535-7163.Mct-10-0728  0.395
2011 Wang Y, Yu Y, Tsuyada A, Ren X, Wu X, Stubblefield K, Rankin-Gee EK, Wang SE. Transforming growth factor-Β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM Oncogene. 30: 1470-1480. PMID 21102523 DOI: 10.1038/Onc.2010.531  0.346
2011 Yang L, Wu X, Deng X, Lau S, Somlo G, Yen Y. Abstract 1196: FZD7 plays a critical role in triple negative breast cancer proliferation Cancer Research. 71: 1196-1196. DOI: 10.1158/1538-7445.Am2011-1196  0.324
2010 Gencheva M, Lin TY, Wu X, Yang L, Richard C, Jones M, Lin SB, Lin RJ. Nuclear retention of unspliced pre-mRNAs by mutant DHX16/hPRP2, a spliceosomal DEAH-box protein. The Journal of Biological Chemistry. 285: 35624-32. PMID 20841358 DOI: 10.1074/Jbc.M110.122309  0.306
2010 Weng L, Wu X, Gao H, Mu B, Li X, Wang JH, Guo C, Jin JM, Chen Z, Covarrubias M, Yuan YC, Weiss LM, Wu H. MicroRNA profiling of clear cell renal cell carcinoma by whole-genome small RNA deep sequencing of paired frozen and formalin-fixed, paraffin-embedded tissue specimens. The Journal of Pathology. 222: 41-51. PMID 20593407 DOI: 10.1002/Path.2736  0.329
2010 Tommasi S, Kim SI, Zhong X, Wu X, Pfeifer GP, Besaratinia A. Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells. Plos One. 5: e10594. PMID 20485678 DOI: 10.1371/Journal.Pone.0010594  0.311
2010 Wu X, Rauch TA, Zhong X, Bennett WP, Latif F, Krex D, Pfeifer GP. CpG island hypermethylation in human astrocytomas. Cancer Research. 70: 2718-27. PMID 20233874 DOI: 10.1158/0008-5472.Can-09-3631  0.304
2010 Wu H, Weng L, Wu X, Gao H, Mu B, Li X, Jin J, Wang J, Guo C, Chen Z, Weiss L. Abstract LB-356: Characterization of microRNA expression of clear cell renal cell carcinoma by whole genome small RNA deep sequencing using human tissue cohort Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-356  0.312
2010 Wu H, Weng L, Wu X, Li X, Pal S, Jin J, Nelson R, Guo C, Onami S, Ruel N, Covarrubias M, Gao H, Mu B, Figlin R, Weiss L. Abstract LB-275: 5-miRNA signature to predict clear cell renal cell carcinoma metastasis and prognosis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-275  0.315
2010 Chen Z, liu Z, Wu X, Li W, Garcia-Aguilar J. Abstract 2694: DNA copy number aberrant profiles predict complete pathologic tumor response to preoperative chemoradiation therapy in locally advanced rectal cancer Cancer Research. 70: 2694-2694. DOI: 10.1158/1538-7445.Am10-2694  0.344
2009 Tommasi S, Karm DL, Wu X, Yen Y, Pfeifer GP. Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer. Breast Cancer Research : Bcr. 11: R14. PMID 19250546 DOI: 10.1186/Bcr2233  0.322
2009 Rauch TA, Wu X, Zhong X, Riggs AD, Pfeifer GP. A human B cell methylome at 100-base pair resolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 671-8. PMID 19139413 DOI: 10.1073/Pnas.0812399106  0.315
2008 Adams LS, Phung S, Wu X, Ki L, Chen S. White button mushroom (Agaricus bisporus) exhibits antiproliferative and proapoptotic properties and inhibits prostate tumor growth in athymic mice. Nutrition and Cancer. 60: 744-56. PMID 19005974 DOI: 10.1080/01635580802192866  0.359
2008 Miao F, Wu X, Zhang L, Riggs AD, Natarajan R. Histone methylation patterns are cell-type specific in human monocytes and lymphocytes and well maintained at core genes. Journal of Immunology (Baltimore, Md. : 1950). 180: 2264-9. PMID 18250434 DOI: 10.4049/Jimmunol.180.4.2264  0.327
2008 Rauch TA, Zhong X, Wu X, Wang M, Kernstine KH, Wang Z, Riggs AD, Pfeifer GP. High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 252-7. PMID 18162535 DOI: 10.1073/Pnas.0710735105  0.325
2007 Rauch T, Wang Z, Zhang X, Zhong X, Wu X, Lau SK, Kernstine KH, Riggs AD, Pfeifer GP. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay. Proceedings of the National Academy of Sciences of the United States of America. 104: 5527-32. PMID 17369352 DOI: 10.1073/Pnas.0701059104  0.337
2007 Miao F, Wu X, Zhang L, Yuan YC, Riggs AD, Natarajan R. Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. The Journal of Biological Chemistry. 282: 13854-63. PMID 17339327 DOI: 10.1074/Jbc.M609446200  0.304
2006 Rauch T, Li H, Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Research. 66: 7939-47. PMID 16912168 DOI: 10.1158/0008-5472.Can-06-1888  0.336
2006 Li L, Wu X, Radich JP, Zhao LP, Francisco L, Komiya A, Damasco H, Forman SJ, Bhatia S, Bhatia R. Altered Gene Expression in CD34+ Cells from PBSC Grafts from Patients Developing t-MDS Following Autologous Transplantation for Lymphoma. Blood. 108: 2326-2326. DOI: 10.1182/Blood.V108.11.2326.2326  0.329
2005 Daniels T, Zhang J, Gutierrez I, Elliot ML, Yamada B, Heeb MJ, Sheets SM, Wu X, Casiano CA. Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis. The Prostate. 62: 14-26. PMID 15389814 DOI: 10.1002/Pros.20112  0.697
2005 Li L, Modi R, Wu X, Forman SJ, Bhatia R. The MDS-Associated Gene DLK Modulates Gene Expression in Human Myeloid Cells by Altering the Activity of Multiple Transcription Factors. Blood. 106: 3428-3428. DOI: 10.1182/Blood.V106.11.3428.3428  0.366
2002 Wu X, Daniels T, Molinaro C, Lilly MB, Casiano CA. Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders. Cell Death and Differentiation. 9: 915-25. PMID 12181742 DOI: 10.1038/Sj.Cdd.4401063  0.687
2001 Wu X, Molinaro C, Johnson N, Casiano CA. Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity. Arthritis and Rheumatism. 44: 2642-52. PMID 11710720 DOI: 10.1002/1529-0131(200111)44:11<2642::Aid-Art444>3.0.Co;2-8  0.57
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