Gerd Pfeifer - Publications

Affiliations: 
Graduate School of Biological Sciences City of Hope's Irell & Manella Graduate School of Biomedical Sciences 
Area:
Genetics, Biochemistry

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Blanchett R, Lau KH, Pfeifer GP. Homeobox and Polycomb target gene methylation in human solid tumors. Scientific Reports. 14: 13912. PMID 38886487 DOI: 10.1038/s41598-024-64569-5  0.347
2023 Cui W, Huang Z, Jin SG, Johnson J, Lau KH, Hostetter G, Pfeifer GP. Deficiency of the Polycomb protein RYBP and TET methylcytosine oxidases promotes extensive CpG island hypermethylation and malignant transformation. Cancer Research. PMID 37272752 DOI: 10.1158/0008-5472.CAN-23-0269  0.353
2022 Meng Y, Wang G, He H, Lau KH, Hurt A, Bixler BJ, Parham A, Jin SG, Xu X, Vasquez KM, Pfeifer GP, Szabó PE. Z-DNA is remodelled by ZBTB43 in prospermatogonia to safeguard the germline genome and epigenome. Nature Cell Biology. PMID 35787683 DOI: 10.1038/s41556-022-00941-9  0.355
2022 Cui W, Huang Z, Pfeifer GP. Lack of Major Genome-Wide DNA Methylation Changes in Succinate-Treated Human Epithelial Cells. International Journal of Molecular Sciences. 23. PMID 35628470 DOI: 10.3390/ijms23105663  0.388
2021 Kim SI, Pfeifer GP. The epigenetic DNA modification 5-carboxylcytosine promotes high levels of cyclobutane pyrimidine dimer formation upon UVB irradiation. Genome Instability & Disease. 2: 59-69. PMID 34485825 DOI: 10.1007/s42764-020-00030-x  0.318
2021 Huang Z, Yu J, Cui W, Johnson BK, Kim K, Pfeifer GP. The chromosomal protein SMCHD1 regulates DNA methylation and the 2c-like state of embryonic stem cells by antagonizing TET proteins. Science Advances. 7. PMID 33523915 DOI: 10.1126/sciadv.abb9149  0.305
2019 Hahn MA, Jin SG, Li AX, Liu J, Huang Z, Wu X, Kim BW, Johnson J, Bilbao AV, Tao S, Yim JA, Fong Y, Goebbels S, Schwab MH, Lu Q, ... Pfeifer GP, et al. Reprogramming of DNA methylation at NEUROD2-bound sequences during cortical neuron differentiation. Science Advances. 5: eaax0080. PMID 31681843 DOI: 10.1126/Sciadv.Aax0080  0.345
2019 Zeng TB, Han L, Pierce N, Pfeifer GP, Szabó PE. EHMT2 and SETDB1 protect the maternal pronucleus from 5mC oxidation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31088968 DOI: 10.1073/pnas.1819946116  0.301
2018 Pfeifer GP. Defining Driver DNA Methylation Changes in Human Cancer. International Journal of Molecular Sciences. 19. PMID 29649096 DOI: 10.3390/ijms19041166  0.405
2017 Hanley MP, Hahn MA, Li AX, Wu X, Lin J, Wang J, Choi AH, Ouyang Z, Fong Y, Pfeifer GP, Devers TJ, Rosenberg DW. Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia. Oncogene. PMID 28459462 DOI: 10.1038/Onc.2017.130  0.387
2016 Iqbal K, Tran DA, Li AX, Warden C, Bai AY, Singh P, Madaj ZB, Winn ME, Wu X, Pfeifer GP, Szabó PE. High type I error and misrepresentations in search for transgenerational epigenetic inheritance: response to Guerrero-Bosagna. Genome Biology. 17: 154. PMID 27411809 DOI: 10.1186/S13059-016-0981-5  0.563
2016 Pfeifer GP. Epigenetics: An elusive DNA base in mammals. Nature. PMID 27027294 DOI: 10.1038/nature17315  0.352
2015 Jin SG, Xiong W, Wu X, Yang L, Pfeifer GP. The DNA methylation landscape of human melanoma. Genomics. PMID 26384656 DOI: 10.1016/J.Ygeno.2015.09.004  0.386
2015 Jung M, Kadam S, Xiong W, Rauch TA, Jin SG, Pfeifer GP. MIRA-seq for DNA methylation analysis of CpG islands. Epigenomics. 1-12. PMID 25881900 DOI: 10.2217/Epi.15.33  0.603
2015 Iqbal K, Tran DA, Li AX, Warden C, Bai AY, Singh P, Wu X, Pfeifer GP, Szabó PE. Deleterious effects of endocrine disruptors are corrected in the mammalian germline by epigenome reprogramming. Genome Biology. 16: 59. PMID 25853433 DOI: 10.1186/S13059-015-0619-Z  0.571
2015 Jung M, Pfeifer GP. Aging and DNA methylation. Bmc Biology. 13: 7. PMID 25637097 DOI: 10.1186/s12915-015-0118-4  0.344
2014 Hahn MA, Szabó PE, Pfeifer GP. 5-Hydroxymethylcytosine: a stable or transient DNA modification? Genomics. 104: 314-23. PMID 25181633 DOI: 10.1016/j.ygeno.2014.08.015  0.355
2014 Pfeifer GP, Xiong W, Hahn MA, Jin SG. The role of 5-hydroxymethylcytosine in human cancer. Cell and Tissue Research. 356: 631-41. PMID 24816989 DOI: 10.1007/s00441-014-1896-7  0.304
2014 Hahn MA, Li AX, Wu X, Yang R, Drew DA, Rosenberg DW, Pfeifer GP. Loss of the polycomb mark from bivalent promoters leads to activation of cancer-promoting genes in colorectal tumors. Cancer Research. 74: 3617-29. PMID 24786786 DOI: 10.1158/0008-5472.Can-13-3147  0.349
2013 Lahtz C, Kim SI, Bates SE, Li AX, Wu X, Pfeifer GP. UVB irradiation does not directly induce detectable changes of DNA methylation in human keratinocytes. F1000research. 2: 45. PMID 24555035 DOI: 10.12688/F1000Research.2-45.V1  0.387
2013 Liu S, Dunwell TL, Pfeifer GP, Dunwell JM, Ullah I, Wang Y. Detection of oxidation products of 5-methyl-2'-deoxycytidine in Arabidopsis DNA. Plos One. 8: e84620. PMID 24391970 DOI: 10.1371/Journal.Pone.0084620  0.314
2013 Pfeifer GP, Kadam S, Jin SG. 5-hydroxymethylcytosine and its potential roles in development and cancer. Epigenetics & Chromatin. 6: 10. PMID 23634848 DOI: 10.1186/1756-8935-6-10  0.559
2013 Kalari S, Jung M, Kernstine KH, Takahashi T, Pfeifer GP. The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells Oncogene. 32: 3559-3568. PMID 22907430 DOI: 10.1038/onc.2012.362  0.36
2012 Lahtz C, Bates SE, Jiang Y, Li AX, Wu X, Hahn MA, Pfeifer GP. Gamma irradiation does not induce detectable changes in DNA methylation directly following exposure of human cells. Plos One. 7: e44858. PMID 23024770 DOI: 10.1371/Journal.Pone.0044858  0.315
2012 Rauch TA, Wang Z, Wu X, Kernstine KH, Riggs AD, Pfeifer GP. DNA methylation biomarkers for lung cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 33: 287-96. PMID 22143938 DOI: 10.1007/s13277-011-0282-2  0.363
2011 Gu TP, Guo F, Yang H, Wu HP, Xu GF, Liu W, Xie ZG, Shi L, He X, Jin SG, Iqbal K, Shi YG, Deng Z, Szabó PE, Pfeifer GP, et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature. 477: 606-10. PMID 21892189 DOI: 10.1038/Nature10443  0.361
2011 Abe M, Tsai SY, Jin SG, Pfeifer GP, Szabó PE. Sex-specific dynamics of global chromatin changes in fetal mouse germ cells. Plos One. 6: e23848. PMID 21886830 DOI: 10.1371/journal.pone.0023848  0.372
2011 Kang ER, Iqbal K, Tran DA, Rivas GE, Singh P, Pfeifer GP, Szabó PE. Effects of endocrine disruptors on imprinted gene expression in the mouse embryo. Epigenetics : Official Journal of the Dna Methylation Society. 6: 937-50. PMID 21636974 DOI: 10.4161/Epi.6.7.16067  0.533
2011 Hahn MA, Wu X, Li AX, Hahn T, Pfeifer GP. Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks. Plos One. 6: e18844. PMID 21526191 DOI: 10.1371/Journal.Pone.0018844  0.365
2011 Jin SG, Wu X, Li AX, Pfeifer GP. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Research. 39: 5015-24. PMID 21378125 DOI: 10.1093/Nar/Gkr120  0.322
2011 Lahtz C, Pfeifer GP. Epigenetic changes of DNA repair genes in cancer. Journal of Molecular Cell Biology. 3: 51-8. PMID 21278452 DOI: 10.1093/jmcb/mjq053  0.305
2011 Lee DH, Tran DA, Singh P, Oates N, Rivas GE, Larson GP, Pfeifer GP, Szabó PE. MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation. Epigenetics. 6: 212-23. PMID 20948294 DOI: 10.4161/Epi.6.2.13699  0.61
2011 Choi J, Li Y, Guo J, Pei L, Rauch TA, Kramer RS, Macmil SL, Wiley GB, Bennett LB, Schnabel JL, Taylor KH, Kim S, Xu D, Sreekumar A, Pfeifer GP, et al. Correction: Genome-Wide DNA Methylation Maps in Follicular Lymphoma Cells Determined by Methylation-Enriched Bisulfite Sequencing Plos One. 6. DOI: 10.1371/annotation/ef58e5ee-1aaf-47b8-a0c5-1f1bf6886a8c  0.352
2010 Lee DH, Singh P, Tsai SY, Oates N, Spalla A, Spalla C, Brown L, Rivas G, Larson G, Rauch TA, Pfeifer GP, Szabó PE. CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-Igf2 imprinting control region in prospermatogonia. Plos Genetics. 6: e1001224. PMID 21124827 DOI: 10.1371/journal.pgen.1001224  0.336
2010 Kim SI, Hollstein M, Pfeifer GP, Besaratinia A. Unveiling the methylation status of CpG dinucleotides in the substituted segment of the human p53 knock-in (Hupki) mouse genome. Molecular Carcinogenesis. 49: 999-1006. PMID 20945503 DOI: 10.1002/mc.20683  0.396
2010 Choi JH, Li Y, Guo J, Pei L, Rauch TA, Kramer RS, Macmil SL, Wiley GB, Bennett LB, Schnabel JL, Taylor KH, Kim S, Xu D, Sreekumar A, Pfeifer GP, et al. Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing. Plos One. 5. PMID 20927367 DOI: 10.1371/Journal.Pone.0013020  0.345
2010 Kalari S, Pfeifer GP. Identification of driver and passenger DNA methylation in cancer by epigenomic analysis. Advances in Genetics. 70: 277-308. PMID 20920752 DOI: 10.1016/B978-0-12-380866-0.60010-1  0.408
2010 Tommasi S, Kim SI, Zhong X, Wu X, Pfeifer GP, Besaratinia A. Investigating the epigenetic effects of a prototype smoke-derived carcinogen in human cells. Plos One. 5: e10594. PMID 20485678 DOI: 10.1371/Journal.Pone.0010594  0.421
2010 Nguyen A, Rauch TA, Pfeifer GP, Hu VW. Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3036-51. PMID 20375269 DOI: 10.1096/Fj.10-154484  0.349
2010 Jin SG, Kadam S, Pfeifer GP. Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine. Nucleic Acids Research. 38: e125. PMID 20371518 DOI: 10.1093/Nar/Gkq223  0.614
2010 Rauch TA, Pfeifer GP. DNA methylation profiling using the methylated-CpG island recovery assay (MIRA). Methods (San Diego, Calif.). 52: 213-7. PMID 20304072 DOI: 10.1016/j.ymeth.2010.03.004  0.418
2010 Wu X, Rauch TA, Zhong X, Bennett WP, Latif F, Krex D, Pfeifer GP. CpG island hypermethylation in human astrocytomas. Cancer Research. 70: 2718-27. PMID 20233874 DOI: 10.1158/0008-5472.Can-09-3631  0.31
2010 Hahn MA, Pfeifer GP. Methods for genome-wide analysis of DNA methylation in intestinal tumors. Mutation Research. 693: 77-83. PMID 19854208 DOI: 10.1016/j.mrfmmm.2009.10.005  0.424
2010 Hill V, Hesson L, Dansranjavin T, Dallol A, Bieche I, Tommasi S, Dobbins T, Gentle D, Euhus D, Dammann R, Ward RL, Minna J, Maher ER, Pfeifer G, Latif F. Abstract 165: MIRA (methylated CpG island recovery assay) assay identifies frequently methylated genes in breast cancer Cancer Research. 70: 165-165. DOI: 10.1158/1538-7445.Am10-165  0.404
2009 Pfeifer GP, Rauch TA. DNA methylation patterns in lung carcinomas. Seminars in Cancer Biology. 19: 181-7. PMID 19429482 DOI: 10.1016/j.semcancer.2009.02.008  0.379
2009 Tommasi S, Karm DL, Wu X, Yen Y, Pfeifer GP. Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer. Breast Cancer Research : Bcr. 11: R14. PMID 19250546 DOI: 10.1186/Bcr2233  0.332
2009 Rauch TA, Wu X, Zhong X, Riggs AD, Pfeifer GP. A human B cell methylome at 100-base pair resolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 671-8. PMID 19139413 DOI: 10.1073/Pnas.0812399106  0.381
2009 Rauch TA, Pfeifer GP. The MIRA method for DNA methylation analysis. Methods in Molecular Biology (Clifton, N.J.). 507: 65-75. PMID 18987807 DOI: 10.1007/978-1-59745-522-0_6  0.426
2009 Kuroda A, Rauch TA, Todorov I, Ku HT, Al-Abdullah IH, Kandeel F, Mullen Y, Pfeifer GP, Ferreri K. Correction: Insulin Gene Expression Is Regulated by DNA Methylation Plos One. 4. DOI: 10.1371/ANNOTATION/947A8D4A-3585-4B23-AC84-B47A255A70D9  0.32
2008 Hahn MA, Hahn T, Lee DH, Esworthy RS, Kim BW, Riggs AD, Chu FF, Pfeifer GP. Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. Cancer Research. 68: 10280-9. PMID 19074896 DOI: 10.1158/0008-5472.CAN-08-1957  0.41
2008 Jin SG, Tsark W, Szabó PE, Pfeifer GP. Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 3435-43. PMID 18942147 DOI: 10.1002/dvdy.21767  0.351
2008 Jin SG, Guo C, Pfeifer GP. GADD45A does not promote DNA demethylation. Plos Genetics. 4: e1000013. PMID 18369439 DOI: 10.1371/journal.pgen.1000013  0.377
2008 Rauch TA, Zhong X, Wu X, Wang M, Kernstine KH, Wang Z, Riggs AD, Pfeifer GP. High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 105: 252-7. PMID 18162535 DOI: 10.1073/Pnas.0710735105  0.398
2007 Pfeifer GP, Wang Z, Riggs AD, Rauch TA. Methylated-CpG island recovery assay-assisted microarrays for cancer diagnosis. Expert Opinion On Medical Diagnostics. 1: 99-108. PMID 23489272 DOI: 10.1517/17530059.1.1.99  0.413
2007 Kim SI, Pfeifer GP, Besaratinia A. Lack of mutagenicity of acrolein-induced DNA adducts in mouse and human cells. Cancer Research. 67: 11640-7. PMID 18089793 DOI: 10.1158/0008-5472.CAN-07-2528  0.367
2007 Seidel C, Schagdarsurengin U, Blümke K, Würl P, Pfeifer GP, Hauptmann S, Taubert H, Dammann R. Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma. Molecular Carcinogenesis. 46: 865-71. PMID 17538946 DOI: 10.1002/mc.20317  0.308
2007 Rauch T, Wang Z, Zhang X, Zhong X, Wu X, Lau SK, Kernstine KH, Riggs AD, Pfeifer GP. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay. Proceedings of the National Academy of Sciences of the United States of America. 104: 5527-32. PMID 17369352 DOI: 10.1073/Pnas.0701059104  0.383
2006 Goren A, Simchen G, Fibach E, Szabo PE, Tanimoto K, Chakalova L, Pfeifer GP, Fraser PJ, Engel JD, Cedar H. Fine tuning of globin gene expression by DNA methylation. Plos One. 1: e46. PMID 17183675 DOI: 10.1371/journal.pone.0000046  0.368
2006 Rauch T, Li H, Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Research. 66: 7939-47. PMID 16912168 DOI: 10.1158/0008-5472.Can-06-1888  0.431
2006 Li H, Rauch T, Chen ZX, Szabó PE, Riggs AD, Pfeifer GP. The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells. The Journal of Biological Chemistry. 281: 19489-500. PMID 16682412 DOI: 10.1074/jbc.M513249200  0.343
2006 Pfeifer GP. Measuring the formation and repair of DNA damage by ligation-mediated PCR Methods in Molecular Biology (Clifton, N.J.). 314: 201-214. PMID 16673883  0.328
2005 Besaratinia A, Pfeifer GP. Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis. Carcinogenesis. 27: 1526-37. PMID 16344267 DOI: 10.1093/carcin/bgi311  0.301
2005 Rauch T, Pfeifer GP. Methylated-CpG island recovery assay: a new technique for the rapid detection of methylated-CpG islands in cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 85: 1172-80. PMID 16025148 DOI: 10.1038/labinvest.3700311  0.409
2005 Castanotto D, Tommasi S, Li M, Li H, Yanow S, Pfeifer GP, Rossi JJ. Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 179-83. PMID 15963934 DOI: 10.1016/J.Ymthe.2005.03.003  0.378
2005 Besaratinia A, Pfeifer GP. Investigating DNA adduct-targeted mutagenicity of tamoxifen: preferential formation of tamoxifen-DNA adducts in the human p53 gene in SV40 immortalized hepatocytes but not endometrial carcinoma cells. Biochemistry. 44: 8418-27. PMID 15938631 DOI: 10.1021/bi0503753  0.312
2005 Jin SG, Jiang CL, Rauch T, Li H, Pfeifer GP. MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing. The Journal of Biological Chemistry. 280: 12700-9. PMID 15701600 DOI: 10.1074/jbc.M413492200  0.363
2004 Choi JH, Pfeifer GP. DNA damage and mutations produced by chloroacetaldehyde in a CpG-methylated target gene. Mutation Research. 568: 245-56. PMID 15542111 DOI: 10.1016/j.mrfmmm.2004.09.004  0.367
2004 Jiang CL, Jin SG, Pfeifer GP. MBD3L1 is a transcriptional repressor that interacts with methyl-CpG-binding protein 2 (MBD2) and components of the NuRD complex. The Journal of Biological Chemistry. 279: 52456-64. PMID 15456747 DOI: 10.1074/jbc.M409149200  0.351
2004 Yoon JH, Iwai S, O'Connor TR, Pfeifer GP. Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. Nucleic Acids Research. 31: 5399-404. PMID 12954776 DOI: 10.1093/nar/gkg730  0.356
2002 Jiang CL, Jin SG, Lee DH, Lan ZJ, Xu X, O'Connor TR, Szabó PE, Mann JR, Cooney AJ, Pfeifer GP. MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor. Genomics. 80: 621-9. PMID 12504854 DOI: 10.1006/geno.2002.7001  0.342
2002 Tang MS, Pfeifer GP, Denissenko MF, Feng Z, Hu W, Pao A, Zheng Y, Zheng JB, Li H, Chen JX. Mapping polycyclic aromatic hydrocarbon and aromatic amine-induced DNA damage in cancer-related genes at the sequence level. International Journal of Hygiene and Environmental Health. 205: 103-13. PMID 12018002 DOI: 10.1078/1438-4639-00135  0.328
2002 Szabó PE, Mann JR, Pfeifer GP. Methylation analysis by chemical DNA sequencing. Methods in Molecular Biology (Clifton, N.J.). 200: 29-41. PMID 11951653 DOI: 10.1385/1-59259-182-5:029  0.372
2001 Arlt VM, Schmeiser HH, Pfeifer GP. Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR. Carcinogenesis. 22: 133-40. PMID 11159751 DOI: 10.1093/carcin/22.1.133  0.306
2000 Miao F, Bouziane M, Dammann R, Masutani C, Hanaoka F, Pfeifer G, O'Connor TR. 3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins. Journal of Biological Chemistry. 275: 28433-28438. PMID 10854423 DOI: 10.1074/Jbc.M001064200  0.32
2000 Szabó P, Tang SH, Rentsendorj A, Pfeifer GP, Mann JR. Maternal-specific footprints at putative CTCF sites in the H19 imprinting control region give evidence for insulator function. Current Biology : Cb. 10: 607-10. PMID 10837224 DOI: 10.1016/S0960-9822(00)00489-9  0.3
2000 Pfeifer GP, Tang M, Denissenko MF. Mutation hotspots and DNA methylation. Current Topics in Microbiology and Immunology. 249: 1-19. PMID 10802935 DOI: 10.1007/978-3-642-59696-4_1  0.356
1999 Tang MS, Zheng JB, Denissenko MF, Pfeifer GP, Zheng Y. Use of UvrABC nuclease to quantify benzo[a]pyrene diol epoxide-DNA adduct formation at methylated versus unmethylated CpG sites in the p53 gene. Carcinogenesis. 20: 1085-9. PMID 10357792 DOI: 10.1093/Carcin/20.6.1085  0.34
1999 Denissenko MF, Cahill J, Koudriakova TB, Gerber N, Pfeifer GP. Quantitation and mapping of aflatoxin B1-induced DNA damage in genomic DNA using aflatoxin B1-8,9-epoxide and microsomal activation systems. Mutation Research. 425: 205-11. PMID 10216213 DOI: 10.1016/S0027-5107(99)00038-X  0.326
1998 You YH, Halangoda A, Buettner V, Hill K, Sommer S, Pfeifer G. Methylation of CpG dinucleotides in the lacI gene of the Big Blue® transgenic mouse Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 420: 55-65. PMID 9838042 DOI: 10.1016/S1383-5718(98)00147-8  0.485
1998 Tu Y, Dammann R, Pfeifer GP. Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. Journal of Molecular Biology. 284: 297-311. PMID 9813119 DOI: 10.1006/jmbi.1998.2176  0.303
1998 Szabó PE, Pfeifer GP, Mann JR. Characterization of novel parent-specific epigenetic modifications upstream of the imprinted mouse H19 gene. Molecular and Cellular Biology. 18: 6767-76. PMID 9774690 DOI: 10.1128/MCB.18.11.6767  0.371
1997 Denissenko MF, Chen JX, Tang MS, Pfeifer GP. Cytosine methylation determines hot spots of DNA damage in the human P53 gene. Proceedings of the National Academy of Sciences of the United States of America. 94: 3893-8. PMID 9108075 DOI: 10.1073/Pnas.94.8.3893  0.401
1997 Tornaletti S, Bates S, Pfeifer GP. A high-resolution analysis of chromatin structure along p53 sequences. Molecular Carcinogenesis. 17: 192-201. PMID 8989912 DOI: 10.1002/(SICI)1098-2744(199612)17:4<192::AID-MC2>3.0.CO;2-G  0.31
1997 Denissenko M, Pfeifer G, Pao A, Tang M. P V.10 Repair of benzo[a]pyrene diol epoxide DNA adducts in the human P53 gene at nucleotide resolution Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379: S36. DOI: 10.1016/S0027-5107(97)82716-9  0.331
1993 Pfeifer GP, Drouin R, Holmquist GP. Detection of DNA adducts at the DNA sequence level by ligation-mediated PCR Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 288: 39-46. PMID 7686264 DOI: 10.1016/0027-5107(93)90206-U  0.303
1991 Pfeifer GP, Drouin R, Riggs AD, Holmquist GP. In vivo mapping of a DNA adduct at nucleotide resolution: Detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction Proceedings of the National Academy of Sciences of the United States of America. 88: 1374-1378. PMID 1996338 DOI: 10.1073/pnas.88.4.1374  0.334
1990 Pfeifer GP, Steigerwald SD, Hansen RS, Gartler SM, Riggs AD. Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proceedings of the National Academy of Sciences of the United States of America. 87: 8252-6. PMID 2236038 DOI: 10.1073/pnas.87.21.8252  0.302
1990 Pfeifer GP, Tanguay RL, Steigerwald SD, Riggs AD. In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1. Genes & Development. 4: 1277-87. PMID 2227409 DOI: 10.1101/gad.4.8.1277  0.358
1990 Steigerwald SD, Pfeifer GP, Riggs AD. Ligation-mediated PCR improves the sensitivity of methylation analysis by restriction enzymes and detection of specific DNA strand breaks. Nucleic Acids Research. 18: 1435-9. PMID 2158077 DOI: 10.1093/nar/18.6.1435  0.384
1989 Pfeifer GP, Steigerwald SD, Mueller PR, Wold B, Riggs AD. Genomic sequencing and methylation analysis by ligation mediated PCR Science. 246: 810-813. PMID 2814502 DOI: 10.1126/Science.2814502  0.33
1988 Vogel MC, Papadopoulos T, Müller-Hermelink HK, Drahovsky D, Pfeifer GP. Intracellular distribution of DNA methyltransferase during the cell cycle. Febs Letters. 236: 9-13. PMID 3402620 DOI: 10.1016/0014-5793(88)80275-8  0.317
1988 Steigerwald SD, Pfeifer GP. Variable DNA methylation changes during differentiation of human melanoma cells. Experimental Cell Research. 178: 41-50. PMID 2457505 DOI: 10.1016/0014-4827(88)90376-X  0.387
1986 Pfeifer GP, Drahovsky D. Preferential binding of DNA methyltransferase and increased de novo methylation of deoxyinosine containing DNA. Febs Letters. 207: 75-8. PMID 3770195 DOI: 10.1016/0014-5793(86)80015-1  0.309
1985 Pfeifer G, Spiess E, Grünwald S, Boehm T, Drahovsky D. Mouse DNA-cytosine-5-methyltransferase: sequence specificity of the methylation reaction and electron microscopy of enzyme-DNA complexes. The Embo Journal. 4: 2879-2884. DOI: 10.1002/j.1460-2075.1985.tb04017.x  0.327
1984 Pfeifer GP, Grunberger D, Drahovsky D. Impaired enzymatic methylation of BPDE-modified DNA. Carcinogenesis. 5: 931-5. PMID 6428767 DOI: 10.1093/Carcin/5.7.931  0.351
1983 Pfeifer GP, Grünwald S, Boehm TL, Drahovsky D. Isolation and characterization of DNA cytosine 5-methyltransferase from human placenta. Biochimica Et Biophysica Acta. 740: 323-30. PMID 6409149 DOI: 10.1016/0167-4781(83)90141-0  0.336
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