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Year Citation  Score
2017 Le Meur G, Lebranchu P, Billaud F, Adjali O, Schmitt S, Bézieau S, Péréon Y, Valabregue R, Ivan C, Darmon C, Moullier P, Rolling F, Weber M. Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29033008 DOI: 10.1016/J.Ymthe.2017.09.014  0.773
2016 Tshilenge KT, Ameline B, Weber M, Mendes-Madeira A, Nedellec S, Biget M, Provost N, Libeau L, Blouin V, Deschamps JY, Le Meur G, Colle MA, Moullier P, Pichard V, Rolling F. Vitrectomy prior to intravitreal injection of AAV2/2 vector promotes efficient transduction of retinal ganglion cells in dogs and non-human primates. Human Gene Therapy Methods. PMID 27229628 DOI: 10.1089/Hgtb.2016.034  0.812
2016 Pichard V, Provost N, Mendes-Madeira A, Libeau L, Hulin P, Tshilenge KT, Biget M, Ameline B, Deschamps JY, Weber M, Le Meur G, Colle MA, Moullier P, Rolling F. AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 867-76. PMID 26857842 DOI: 10.1038/Mt.2016.37  0.825
2016 Pichard V, Provost N, Mendes-Madeira A, Libeau L, Hulin P, Tshilenge KT, Biget M, Ameline B, Deschamps JY, Weber M, Le Meur G, Colle MA, Moullier P, Rolling F. AAV-mediated Gene Therapy Halts Retinal Degeneration in PDE6β-deficient Dogs Molecular Therapy. DOI: 10.1038/mt.2016.37  0.531
2015 Hordeaux J, Dubreil L, Deniaud J, Iacobelli F, Moreau S, Ledevin M, Le Guiner C, Blouin V, Le Duff J, Mendes-Madeira A, Rolling F, Cherel Y, Moullier P, Colle MA. Efficient central nervous system AAVrh10-mediated intrathecal gene transfer in adult and neonate rats. Gene Therapy. 22: 316-24. PMID 25588740 DOI: 10.1038/Gt.2014.121  0.334
2014 Le Guiner C, Stieger K, Toromanoff A, Guilbaud M, Mendes-Madeira A, Devaux M, Guigand L, Cherel Y, Moullier P, Rolling F, Adjali O. Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates. Plos One. 9: e102538. PMID 25248159 DOI: 10.1371/Journal.Pone.0102538  0.73
2014 Klein D, Mendes-Madeira A, Schlegel P, Rolling F, Lorenz B, Haverkamp S, Stieger K. Immuno-histochemical analysis of rod and cone reaction to RPE65 deficiency in the inferior and superior canine retina. Plos One. 9: e86304. PMID 24466015 DOI: 10.1371/Journal.Pone.0086304  0.737
2014 Lhériteau E, Petit L, Weber M, Le Meur G, Deschamps JY, Libeau L, Mendes-Madeira A, Guihal C, François A, Guyon R, Provost N, Lemoine F, Papal S, El-Amraoui A, Colle MA, ... ... Rolling F, et al. Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 265-77. PMID 24091916 DOI: 10.1038/Mt.2013.232  0.806
2012 Petit L, Lhériteau E, Weber M, Le Meur G, Deschamps JY, Provost N, Mendes-Madeira A, Libeau L, Guihal C, Colle MA, Moullier P, Rolling F. Restoration of vision in the pde6β-deficient dog, a large animal model of rod-cone dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2019-30. PMID 22828504 DOI: 10.1038/Mt.2012.134  0.805
2012 Meur GL, Lebranchu P, Pereon Y, Billaud F, Ivan C, Chauveau C, Rolling F, Weber M. Efficacy and safety of gene therapy with AAV4 in childhood blindness due to rpe65 mutations Acta Ophthalmologica. 90: 0-0. DOI: 10.1111/J.1755-3768.2012.4223.X  0.511
2011 Stieger K, Cronin T, Bennett J, Rolling F. Adeno-associated virus mediated gene therapy for retinal degenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 807: 179-218. PMID 22034031 DOI: 10.1007/978-1-61779-370-7_8  0.806
2011 Joussemet B, Belbellaa B, Mendes-Madeira A, Bucher T, Briot-Nivard D, Dubreil L, Colle MA, Cherel Y, Moullier P, Rolling F. Neonatal systemic delivery of scAAV9 in rodents and large animals results in gene transfer to RPE cells in the retina. Experimental Eye Research. 93: 491-502. PMID 21723863 DOI: 10.1016/J.Exer.2011.06.012  0.828
2010 Rolling F. AAV-mediated gene therapy for the treatment of retinal diseases. Current Gene Therapy. 10: 318. PMID 20874705 DOI: 10.2174/156652310793180733  0.564
2010 Stieger K, Chauveau C, Rolling F. Preclinical studies on specific gene therapy for recessive retinal degenerative diseases. Current Gene Therapy. 10: 389-403. PMID 20718697 DOI: 10.2174/156652310793180689  0.811
2010 Lhériteau E, Libeau L, Mendes-Madeira A, Deschamps JY, Weber M, Le Meur G, Provost N, Guihal C, Moullier P, Rolling F. Regulation of retinal function but nonrescue of vision in RPE65-deficient dogs treated with doxycycline-regulatable AAV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1085-93. PMID 20354505 DOI: 10.1038/Mt.2010.46  0.822
2010 Toromanoff A, Adjali O, Larcher T, Hill M, Guigand L, Chenuaud P, Deschamps JY, Gauthier O, Blancho G, Vanhove B, Rolling F, Chérel Y, Moullier P, Anegon I, Le Guiner C. Lack of immunotoxicity after regional intravenous (RI) delivery of rAAV to nonhuman primate skeletal muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 151-60. PMID 19888197 DOI: 10.1038/Mt.2009.251  0.464
2009 Stieger K, Schroeder J, Provost N, Mendes-Madeira A, Belbellaa B, Meur GL, Weber M, Deschamps JY, Lorenz B, Moullier P, Rolling F. Detection of Intact rAAV Particles up to 6 Years After Successful Gene Transfer in the Retina of Dogs and Primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 516-523. PMID 28189016 DOI: 10.1038/mt.2008.283  0.823
2009 Van Vliet K, Mohiuddin Y, McClung S, Blouin V, Rolling F, Moullier P, Agbandje-McKenna M, Snyder RO. Adeno-associated virus capsid serotype identification: Analytical methods development and application. Journal of Virological Methods. 159: 167-77. PMID 19447508 DOI: 10.1016/J.Jviromet.2009.03.020  0.391
2009 Stieger K, Belbellaa B, Le Guiner C, Moullier P, Rolling F. In vivo gene regulation using tetracycline-regulatable systems. Advanced Drug Delivery Reviews. 61: 527-41. PMID 19394373 DOI: 10.1016/J.Addr.2008.12.016  0.793
2009 Stieger K, Lhériteau E, Lhéariteau E, Moullier P, Rolling F. AAV-mediated gene therapy for retinal disorders in large animal models. Ilar Journal. 50: 206-24. PMID 19293463 DOI: 10.1093/Ilar.50.2.206  0.804
2009 Lhériteau E, Libeau L, Stieger K, Deschamps JY, Mendes-Madeira A, Provost N, Lemoine F, Mellersh C, Ellinwood NM, Cherel Y, Moullier P, Rolling F. The RPGRIP1-deficient dog, a promising canine model for gene therapy. Molecular Vision. 15: 349-61. PMID 19223988  0.691
2009 Stieger K, Schroeder J, Provost N, Mendes-Madeira A, Belbellaa B, Le Meur G, Weber M, Deschamps JY, Lorenz B, Moullier P, Rolling F. Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 516-23. PMID 19107120 DOI: 10.1038/Mt.2008.283  0.792
2008 Toromanoff A, Chérel Y, Guilbaud M, Penaud-Budloo M, Snyder RO, Haskins ME, Deschamps JY, Guigand L, Podevin G, Arruda VR, High KA, Stedman HH, Rolling F, Anegon I, Moullier P, et al. Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1291-1299. PMID 28178483 DOI: 10.1038/Mt.2008.87  0.425
2008 Penaud-Budloo M, Le Guiner C, Nowrouzi A, Toromanoff A, Chérel Y, Chenuaud P, Schmidt M, von Kalle C, Rolling F, Moullier P, Snyder RO. Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle. Journal of Virology. 82: 7875-85. PMID 18524821 DOI: 10.1128/Jvi.00649-08  0.43
2008 Stieger K, Colle MA, Dubreil L, Mendes-Madeira A, Weber M, Le Meur G, Deschamps JY, Provost N, Nivard D, Cherel Y, Moullier P, Rolling F. Subretinal delivery of recombinant AAV serotype 8 vector in dogs results in gene transfer to neurons in the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 916-23. PMID 18388922 DOI: 10.1038/Mt.2008.41  0.82
2007 Le Guiner C, Stieger K, Snyder RO, Rolling F, Moullier P. Immune responses to gene product of inducible promoters. Current Gene Therapy. 7: 334-46. PMID 17979680 DOI: 10.2174/156652307782151461  0.703
2007 Stieger K, Mendes-Madeira A, Meur GL, Weber M, Deschamps JY, Nivard D, Provost N, Moullier P, Rolling F. Oral administration of doxycycline allows tight control of transgene expression: a key step towards gene therapy of retinal diseases. Gene Therapy. 14: 1668-73. PMID 17914405 DOI: 10.1038/sj.gt.3303034  0.756
2006 Rolling F, Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Gene therapeutic prospects in early onset of severe retinal dystrophy: restoration of vision in RPE65 Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Bulletin Et Memoires De L'Academie Royale De Medecine De Belgique. 161: 497-508; discussion . PMID 17503728  0.846
2006 Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Gene Therapy. 14: 292-303. PMID 17024105 DOI: 10.1038/Sj.Gt.3302861  0.801
2006 Stieger K, Le Meur G, Lasne F, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Martin L, Moullier P, Rolling F. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 967-75. PMID 16442848 DOI: 10.1016/J.Ymthe.2005.12.001  0.831
2006 Toromanoff A, Hill M, Cherel Y, Deschamps J, Gauthier O, Vanhove B, Rolling F, Moullier P, Anegon I, Guiner CL. 974. Constitutive Expression of a Mutated Form of CTLA4Ig after Gene Transfer Is Well Tolerated and Prevents Immune Responses Against an Immunogenic Transgene in Nonhuman Primates Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1067  0.453
2006 Toromanoff A, Cherel Y, Deschamps J, Arruda VR, High KA, Stedman HH, Haskins ME, Rolling F, Anegon I, Moullier P, Le Guiner C. 39. Evaluation of rAAV-1 vs rAAV-8 Vectors and Their Mode of Delivery in Nonhuman Primate Skeletal Muscle Molecular Therapy. 13: S16-S17. DOI: 10.1016/J.Ymthe.2006.08.052  0.422
2005 Smith JR, Verwaerde C, Rolling F, Naud MC, Delanoye A, Thillaye-Goldenberg B, Apparailly F, De Kozak Y. Tetracycline-inducible viral interleukin-10 intraocular gene transfer, using adeno-associated virus in experimental autoimmune uveoretinitis Human Gene Therapy. 16: 1037-1046. PMID 16149902 DOI: 10.1089/hum.2005.16.1037  0.427
2005 Auricchio A, Rolling F. Adeno-associated viral vectors for retinal gene transfer and treatment of retinal diseases. Current Gene Therapy. 5: 339-48. PMID 15975011 DOI: 10.2174/1566523054065020  0.602
2005 Fraefel C, Mendes-Madeira A, Mabon O, Lefebvre A, Meur GL, Ackermann M, Moullier P, Rolling F. In vivo gene transfer to the rat retina using herpes simplex virus type 1 (HSV-1)-based amplicon vectors. Gene Therapy. 12: 1283-1288. PMID 15889134 DOI: 10.1038/Sj.Gt.3302553  0.492
2005 Le Meur G, Weber M, Péréon Y, Mendes-Madeira A, Nivard D, Deschamps JY, Moullier P, Rolling F. Postsurgical assessment and long-term safety of recombinant adeno-associated virus-mediated gene transfer into the retinas of dogs and primates. Archives of Ophthalmology (Chicago, Ill. : 1960). 123: 500-6. PMID 15824224 DOI: 10.1001/Archopht.123.4.500  0.771
2005 Provost N, Le Meur G, Weber M, Mendes-Madeira A, Podevin G, Cherel Y, Colle MA, Deschamps JY, Moullier P, Rolling F. Biodistribution of rAAV vectors following intraocular administration: evidence for the presence and persistence of vector DNA in the optic nerve and in the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 275-83. PMID 15668139 DOI: 10.1016/J.Ymthe.2004.09.022  0.755
2004 Rolling F. Recombinant AAV-mediated gene transfer to the retina: gene therapy perspectives Gene Therapy. 11. PMID 15454954 DOI: 10.1038/Sj.Gt.3302366  0.692
2004 Bellodi-Privato M, Le Meur G, Aubert D, Mendes-Madera A, Pichard V, Rolling F, Ferry N. AAV gene transfer to the retina does not protect retrovirally transduced hepatocytes from the immune response. Journal of Molecular Medicine (Berlin, Germany). 82: 403-10. PMID 15042302 DOI: 10.1007/S00109-004-0537-0  0.788
2003 Folliot S, Briot D, Conrath H, Provost N, Cherel Y, Moullier P, Rolling F. Sustained tetracycline-regulated transgene expression in vivo in rat retinal ganglion cells using a single type 2 adeno-associated viral vector. The Journal of Gene Medicine. 5: 493-501. PMID 12797114 DOI: 10.1002/Jgm.367  0.606
2003 Weber M, Rabinowitz J, Provost N, Conrath H, Folliot S, Briot D, Chérel Y, Chenuaud P, Samulski J, Moullier P, Rolling F. Recombinant adeno-associated virus serotype 4 mediates unique and exclusive long-term transduction of retinal pigmented epithelium in rat, dog, and nonhuman primate after subretinal delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 774-81. PMID 12788651 DOI: 10.1016/S1525-0016(03)00098-4  0.634
2002 Brument N, Morenweiser R, Blouin V, Toublanc E, Raimbaud I, Chérel Y, Folliot S, Gaden F, Boulanger P, Kroner-Lux G, Moullier P, Rolling F, Salvetti A. A versatile and scalable two-step ion-exchange chromatography process for the purification of recombinant adeno-associated virus serotypes-2 and -5. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 678-86. PMID 12436964 DOI: 10.1006/Mthe.2002.0719  0.349
2002 Duisit G, Conrath H, Saleun S, Folliot S, Provost N, Cosset FL, Sandrin V, Moullier P, Rolling F. Five recombinant simian immunodeficiency virus pseudotypes lead to exclusive transduction of retinal pigmented epithelium in rat. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 446-54. PMID 12377185 DOI: 10.1006/Mthe.2002.0690  0.404
2002 Rabinowitz JE, Rolling F, Li C, Conrath H, Xiao W, Xiao X, Samulski RJ. Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity. Journal of Virology. 76: 791-801. PMID 11752169 DOI: 10.1128/Jvi.76.2.791-801.2002  0.466
2000 Rolling F, Shen WY, Barnett NL, Tabarias H, Kanagasingam Y, Constable I, Rakoczy PE. long-term real-time monitoring of adeno-associated virus-mediated gene expression in the rat retina Clinical and Experimental Ophthalmology. 28: 382-386. PMID 11097287 DOI: 10.1046/j.1442-9071.2000.00341.x  0.534
1999 Rolling F, Shen WY, Tabarias H, Constable I, Kanagasingam Y, Barry CJ, Rakoczy PE. Evaluation of adeno-associated virus-mediated gene transfer into the rat retina by clinical fluorescence photography Human Gene Therapy. 10: 641-648. PMID 10094207 DOI: 10.1089/10430349950018715  0.5
1999 Rakoczy PE, Shen W, Lai M, Rolling F, Constable IJ. Development of gene therapy-based strategies for the treatment of eye diseases Drug Development Research. 46: 277-285. DOI: 10.1002/(SICI)1098-2299(199903/04)46:3/4<277::AID-DDR13>3.0.CO;2-B  0.335
1998 Lai YKY, Rakoczy P, Constable I, Rolling F. Adeno-associated virus-mediated gene transfer into human retinal pigment epithelium cells Australian and New Zealand Journal of Ophthalmology. 26. PMID 9685031 DOI: 10.1111/J.1442-9071.1998.TB01381.X  0.493
1997 Rolling F, Nong Z, Pisvin S, Collen D. Adeno-associated virus-mediated gene transfer into rat carotid arteries. Gene Therapy. 4: 757-61. PMID 9338002 DOI: 10.1038/sj.gt.3300465  0.374
1995 Rolling F, Samulski RJ. AAV as a viral vector for human gene therapy - Generation of recombinant virus Molecular Biotechnology. 3: 9-15. PMID 7606507 DOI: 10.1007/Bf02821330  0.45
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