| Year |
Citation |
Score |
| 2017 |
Singh S, Khan I, Khim S, Seymour B, Sommer K, Wielgosz M, Norgaard Z, Kiem HP, Adair J, Liggitt D, Nienhuis A, Rawlings DJ. Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector. Molecular Therapy. Methods & Clinical Development. 4: 1-16. PMID 28344987 DOI: 10.1016/j.omtm.2016.11.001 |
0.311 |
|
| 2016 |
Zhan J, Johnson IM, Wielgosz M, Nienhuis AW. The identification of hematopoietic-specific regulatory elements for WASp gene expression. Molecular Therapy. Methods & Clinical Development. 3: 16077. PMID 28035317 DOI: 10.1038/mtm.2016.77 |
0.303 |
|
| 2010 |
Wilber A, Tschulena U, Hargrove PW, Kim YS, Persons DA, Barbas CF, Nienhuis AW. A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts. Blood. 115: 3033-41. PMID 20190190 DOI: 10.1182/Blood-2009-08-240556 |
0.303 |
|
| 2002 |
Hanawa H, Persons DA, Nienhuis AW. High-level erythroid lineage-directed gene expression using globin gene regulatory elements after lentiviral vector-mediated gene transfer into primitive human and murine hematopoietic cells. Human Gene Therapy. 13: 2007-16. PMID 12489996 DOI: 10.1089/10430340260395866 |
0.316 |
|
| 2001 |
Persons DA, Allay ER, Sabatino DE, Kelly P, Bodine DM, Nienhuis AW. Functional requirements for phenotypic correction of murine beta-thalassemia: implications for human gene therapy. Blood. 97: 3275-82. PMID 11342459 DOI: 10.1182/Blood.V97.10.3275 |
0.31 |
|
| 1999 |
Feingold EA, Penny LA, Nienhuis AW, Forget BG. An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells. Genomics. 61: 15-23. PMID 10512676 DOI: 10.1006/Geno.1999.5935 |
0.395 |
|
| 1995 |
Farina SF, Girard LJ, Vanin EF, Nienhuis AW, Bodine DM. Dysregulated expression of GATA-1 following retrovirus-mediated gene transfer into murine hematopoietic stem cells increases erythropoiesis. Blood. 86: 4124-33. PMID 7492769 DOI: 10.1182/Blood.V86.11.4124.Bloodjournal86114124 |
0.429 |
|
| 1994 |
Goodman S, Xiao X, Donahue RE, Moulton A, Miller J, Walsh C, Young NS, Samulski RJ, Nienhuis AW. Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. Blood. 84: 1492-500. PMID 8068942 |
0.333 |
|
| 1994 |
Cunningham JM, Purucker ME, Jane SM, Safer B, Vanin EF, Ney PA, Lowrey CH, Nienhuis AW. The regulatory element 3' to the A gamma-globin gene binds to the nuclear matrix and interacts with special A-T-rich binding protein 1 (SATB1), an SAR/MAR-associating region DNA binding protein. Blood. 84: 1298-308. PMID 8049444 DOI: 10.1182/Blood.V84.4.1298.Bloodjournal8441298 |
0.301 |
|
| 1994 |
Walsh CE, Nienhuis AW, Samulski RJ, Brown MG, Miller JL, Young NS, Liu JM. Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector. The Journal of Clinical Investigation. 94: 1440-8. PMID 7929819 DOI: 10.1172/Jci117481 |
0.338 |
|
| 1994 |
Cockayne DA, Bodine DM, Cline A, Nienhuis AW, Dunbar CE. Transgenic mice expressing antisense interleukin-3 RNA develop a B-cell lymphoproliferative syndrome or neurologic dysfunction. Blood. 84: 2699-710. PMID 7919383 DOI: 10.1182/Blood.V84.8.2699.2699 |
0.314 |
|
| 1994 |
Miller JL, Donahue RE, Sellers SE, Samulski RJ, Young NS, Nienhuis AW. Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 10183-7. PMID 7524085 DOI: 10.1073/Pnas.91.21.10183 |
0.364 |
|
| 1994 |
Walsh CE, Grompe M, Vanin E, Buchwald M, Young NS, Nienhuis AW, Liu JM. A functionally active retrovirus vector for gene therapy in Fanconi anemia group C. Blood. 84: 453-9. PMID 7517716 DOI: 10.1182/Blood.V84.2.453.453 |
0.398 |
|
| 1994 |
Dunbar CE, Bodine DM, Sorrentino B, Donahue R, McDonagh K, Cottler-Fox M, O'Shaughnessy J, Cowan K, Carter C, Doren S, Cassell A, Nienhuis AW, Brenner MK. Gene transfer into hematopoietic cells. Implications for cancer therapy Annals of the New York Academy of Sciences. 716: 216-224. PMID 7517651 DOI: 10.1111/J.1749-6632.1994.Tb21714.X |
0.334 |
|
| 1993 |
Walsh CE, Liu JM, Miller JL, Nienhuis AW, Samulski RJ. Gene therapy for human hemoglobinopathies. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 204: 289-300. PMID 8234372 DOI: 10.3181/00379727-204-43665 |
0.407 |
|
| 1993 |
Dunbar CE, Nienhuis AW, Stewart FM, Quesenberry P, O'Shaughnessy J, Cowan K, Cottler-Fox M, Leitman S, Goodman S, Sorrentino BP. Amendment to clinical research projects. Genetic marking with retroviral vectors to study the feasibility of stem cell gene transfer and the biology of hematopoietic reconstitution after autologous transplantation in multiple myeloma, chronic myelogenous leukemia, or metastatic breast cancer. Human Gene Therapy. 4: 205-22. PMID 8098622 DOI: 10.1089/Hum.1993.4.2-205 |
0.3 |
|
| 1993 |
Bodine DM, Moritz T, Donahue RE, Luskey BD, Kessler SW, Martin DI, Orkin SH, Nienhuis AW, Williams DA. Long-term in vivo expression of a murine adenosine deaminase gene in rhesus monkey hematopoietic cells of multiple lineages after retroviral mediated gene transfer into CD34+ bone marrow cells. Blood. 82: 1975-80. PMID 7691243 DOI: 10.1182/Blood.V82.7.1975.Bloodjournal8271975 |
0.428 |
|
| 1993 |
Rodgers GP, Dover GJ, Uyesaka N, Noguchi CT, Schechter AN, Nienhuis AW. Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease. The New England Journal of Medicine. 328: 73-80. PMID 7677965 DOI: 10.1056/Nejm199301143280201 |
0.332 |
|
| 1993 |
Miller J, Walsh C, Ney P, Samulski R, Nienhuis A. Single-copy transduction and expression of human gamma-globin in K562 erythroleukemia cells using recombinant adeno-associated virus vectors: the effect of mutations in NF-E2 and GATA-1 binding motifs within the hypersensitivity site 2 enhancer [published erratum appears in Blood 1995 Feb 1;85(3):862] Blood. 82: 1900-1906. DOI: 10.1182/Blood.V82.6.1900.1900 |
0.384 |
|
| 1992 |
Lowrey CH, Bodine DM, Nienhuis AW. Mechanism of DNase I hypersensitive site formation within the human globin locus control region Proceedings of the National Academy of Sciences of the United States of America. 89: 1143-1147. PMID 1736298 DOI: 10.1073/Pnas.89.3.1143 |
0.362 |
|
| 1992 |
Epstein ND, Fananapazir L, Lin HJ, Mulvihill J, White R, Lalouel JM, Lifton RP, Nienhuis AW, Leppert M. Evidence of genetic heterogeneity in five kindreds with familial hypertrophic cardiomyopathy Circulation. 85: 635-647. PMID 1735158 DOI: 10.1161/01.Cir.85.2.635 |
0.3 |
|
| 1992 |
Walsh CE, Liu JM, Xiao X, Young NS, Nienhuis AW, Samulski RJ. Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proceedings of the National Academy of Sciences of the United States of America. 89: 7257-61. PMID 1323131 DOI: 10.1073/Pnas.89.15.7257 |
0.452 |
|
| 1992 |
Jane SM, Ney PA, Vanin EF, Gumucio DL, Nienhuis AW. Identification of a stage selector element in the human gamma-globin gene promoter that fosters preferential interaction with the 5' HS2 enhancer when in competition with the beta-promoter. The Embo Journal. 11: 2961-2969. DOI: 10.1002/J.1460-2075.1992.Tb05366.X |
0.388 |
|
| 1991 |
Shimada T, Fujii H, Mitsuya H, Nienhuis AW. Targeted and highly efficient gene transfer into CD4+ cells by a recombinant human immunodeficiency virus retroviral vector Journal of Clinical Investigation. 88: 1043-1047. PMID 1885765 DOI: 10.1172/Jci115365 |
0.347 |
|
| 1991 |
Cockayne DA, Abrams JS, Nienhuis AW. Antisense RNA inhibition of hematopoietic growth factor production Growth Factors. 5: 171-181. PMID 1723284 DOI: 10.3109/08977199109000281 |
0.33 |
|
| 1990 |
Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice Journal of Clinical Investigation. 86: 592-599. PMID 2384605 DOI: 10.1172/Jci114749 |
0.315 |
|
| 1990 |
Bodine DM, McDonagh KT, Brandt SJ, Ney PA, Agricola B, Byrne E, Nienhuis AW. Development of a high-titer retrovirus producer cell line capable of gene transfer into thesus monkey hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America. 87: 3738-3742. PMID 2339117 DOI: 10.1073/Pnas.87.10.3738 |
0.405 |
|
| 1990 |
Bodine DM, McDonagh KT, Seidel NE, Nienhuis AW. Development of a high-titer retrovirus producer cell line and strategies for retrovirus-mediated gene transfer into rhesus monkey hematopoietic stem cells. Annals of the New York Academy of Sciences. 612: 415-26. PMID 2291568 DOI: 10.1111/J.1749-6632.1990.Tb24329.X |
0.39 |
|
| 1990 |
Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. Retroviral-mediated transfer of interleukin-6 into hematopoietic cells of mice results in a syndrome resembling Castgleman's disease Current Topics in Microbiology and Immunology. 166: 37-41. PMID 2073814 DOI: 10.1007/978-3-642-75889-8_5 |
0.307 |
|
| 1990 |
Rodgers GP, Dover GJ, Noguchi CT, Schechter AN, Nienhuis AW. Hematologic responses of patients with sickle cell disease to treatment with hydroxyurea New England Journal of Medicine. 322: 1037-1045. PMID 1690857 DOI: 10.1056/Nejm199004123221504 |
0.314 |
|
| 1989 |
Bodine DM, Karlsson S, Papayannopoulou T, Nienhuis AW. Expression of human beta globin genes introduced into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer Progress in Clinical and Biological Research. 316: 219-233. PMID 2694174 |
0.346 |
|
| 1989 |
Bodine DM, Karlsson S, Papayannopoulou T, Nienhuis AW. Introduction and expression of human beta globin genes into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer Progress in Clinical and Biological Research. 319: 589-599; discussion . PMID 2622930 |
0.346 |
|
| 1989 |
Wong PMC, Chung SW, Dunbar CE, Bodine DM, Ruscetti S, Nienhuis AW. Retrovirus-mediated transfer and expression of the interleukin-3 gene in mouse hematopoietic cells result in a myeloproliferative disorder Molecular and Cellular Biology. 9: 798-808. PMID 2565534 DOI: 10.1128/Mcb.9.2.798 |
0.399 |
|
| 1989 |
Lin HJ, Bodine DM, Rutherford TR, Anagnou NP, McDonagh KT, Ley TJ, Nienhuis AW. Regulatory regions flanking the human fetal γ-globin genes Annals of the New York Academy of Sciences. 565: 13-22. PMID 2476058 DOI: 10.1111/J.1749-6632.1989.Tb24145.X |
0.376 |
|
| 1988 |
Karlsson S, Bodine DM, Perry L, Papayannopoulou T, Nienhuis AW. Expression of the human β-globin gene folllowing retroviral-mediated transfer into multipotential hematopoietic progenitors of mice Proceedings of the National Academy of Sciences of the United States of America. 85: 6062-6066. PMID 3413076 DOI: 10.1073/Pnas.85.16.6062 |
0.442 |
|
| 1987 |
Lin HJ, Anagnou NP, Rutherford TR, Shimada T, Nienhuis AW. Activation of the human β-globin promoter in K562 cells by DNA sequences 5' to the fetal γ- or embryonic ζ-globin genes Journal of Clinical Investigation. 80: 374-380. PMID 3611352 DOI: 10.1172/Jci113082 |
0.401 |
|
| 1987 |
Rutherford T, Nienhuis AW. Human globin gene promoter sequences are sufficient for specific expression of a hybrid gene transfected into tissue culture cells Molecular and Cellular Biology. 7: 398-402. PMID 3561396 |
0.309 |
|
| 1987 |
Le Beau MM, Epstein ND, O'Brien SJ, Nienhuis AW, Yang YC, Clark SC, Rowley JD. The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q Proceedings of the National Academy of Sciences of the United States of America. 84: 5913-5917. PMID 3497400 DOI: 10.1073/Pnas.84.16.5913 |
0.321 |
|
| 1987 |
Lin HJ, Rutherford TR, Anagnou NP, Nienhuis AW. Tissue and developmental specificity of globin gene promoters: gene expression in human and mouse erythroleukemia and nonerythroid cells Progress in Clinical and Biological Research. 251: 175-187. PMID 3481076 |
0.309 |
|
| 1987 |
Garver RI, Chytil A, Karlsson S, Fells GA, Brantly ML, Courtney M, Kantoff PW, Nienhuis AW, Anderson WF, Crystal RG. Production of glycosylated physiologically 'normal' human α1-antitrypsin by mouse fibroblasts modified by insertion of a human α1-antitrypsin cDNA using a retroviral vector Proceedings of the National Academy of Sciences of the United States of America. 84: 1050-1054. PMID 3029759 DOI: 10.1073/Pnas.84.4.1050 |
0.418 |
|
| 1987 |
Gillio A, Bordignon C, Kernan N, Kantoff P, Eglitis M, McLachlin J, Karson E, Yu SF, Zwiebel J, Nienhuis A, Karlsson S, Blaese M, Kohn D, Armentano D, Gilboa E, et al. Retroviral vector-mediated gene transfer and expression in nonhuman primates following autologous bone marrow transplantation. Annals of the New York Academy of Sciences. 511: 406-417. PMID 2894194 DOI: 10.1111/J.1749-6632.1987.Tb36270.X |
0.342 |
|
| 1986 |
Karlsson S, Van Doren K, Schweiger SG, Nienhuis AW, Gluzman Y. Stable gene transfer and tissue-specific expression of a human globin gene using adenoviral vectors The Embo Journal. 5: 2377-2385. PMID 3780679 DOI: 10.1002/J.1460-2075.1986.Tb04507.X |
0.446 |
|
| 1986 |
Browning PJ, Bunn HF, Cline A, Shuman M, Nienhuis AW. 'Replacement' of COOH-terminal truncation of v-fms with c-fms sequences markedly reduces transformation potential Proceedings of the National Academy of Sciences of the United States of America. 83: 7800-7804. PMID 3532121 DOI: 10.1073/Pnas.83.20.7800 |
0.356 |
|
| 1986 |
Holt JT, Venkat Gopal T, Moulton AD, Nienhuis AW. Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation Proceedings of the National Academy of Sciences of the United States of America. 83: 4794-4798. PMID 3523478 DOI: 10.1073/Pnas.83.13.4794 |
0.407 |
|
| 1986 |
Anagnou NP, Karlsson S, Moulton AD, Keller G, Nienhuis AW. Promoter sequences required for function of the human gamma globin gene in erythroid cells The Embo Journal. 5: 121-126. PMID 3007109 DOI: 10.1002/J.1460-2075.1986.Tb04185.X |
0.437 |
|
| 1985 |
Nienhuis AW, Franklin Bunn H, Turner PH, Venkat Gopal T, Nash WG, O'Brien SJ, Sherr CJ. Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q- syndrome Cell. 42: 421-428. PMID 4028159 DOI: 10.1016/0092-8674(85)90099-6 |
0.405 |
|
| 1985 |
Roy MS, Rodgers GP, Podgor MJ, Noguchi CT, Nienhuis AW, Schechter AN. Conjunctival sign in sickle cell anaemia: An in-vivo correlate of the extent of red cell heterogeneity British Journal of Ophthalmology. 69: 629-632. PMID 4016063 DOI: 10.1136/Bjo.69.8.629 |
0.341 |
|
| 1985 |
Venkat Gopal T, Shimada T, Baur AW, Nienhuis AW. Contribution of promoter to tissue-specific expression of the mouse immunoglobulin kappa gene Science. 229: 1102-1104. PMID 2994213 DOI: 10.1126/Science.2994213 |
0.399 |
|
| 1985 |
Karlsson S, Humphries RK, Gluzman Y, Nienhuis AW. Transfer of genes into hematopoietic cells using recombinant DNA viruses Proceedings of the National Academy of Sciences of the United States of America. 82: 158-162. PMID 2982141 DOI: 10.1073/Pnas.82.1.158 |
0.402 |
|
| 1985 |
Ley TJ, Nienhuis AW. Induction of hemoglobin F synthesis in patients with beta thalassemia Annual Review of Medicine. 36: 485-498. PMID 2581500 DOI: 10.1146/Annurev.Me.36.020185.002413 |
0.383 |
|
| 1985 |
Humphries RK, Berg P, DiPietro J, Bernstein S, Baur A, Nienhuis AW, Anderson WF. Transfer of human and murine globin-gene sequences into transgenic mice American Journal of Human Genetics. 37: 295-310. PMID 2580434 |
0.31 |
|
| 1985 |
Humphries RK, Dover G, Young NS, Moore JG, Charache S, Ley T, Nienhuis AW. 5-Azacytidine acts directly on both erythroid precursors and progenitors to increase production of fetal hemoglobin Journal of Clinical Investigation. 75: 547-557. PMID 2579100 DOI: 10.1172/Jci111731 |
0.342 |
|
| 1985 |
Anagnou N, Papayannopoulou T, Stamatoyannopoulos G, Nienhuis A. Structurally diverse molecular deletions in the beta-globin gene cluster exhibit an identical phenotype on interaction with the beta S- gene Blood. 65: 1245-1251. DOI: 10.1182/Blood.V65.5.1245.1245 |
0.411 |
|
| 1984 |
Fordis CM, Anagnou NP, Dean A, Nienhuis AW, Schechter AN. A beta-globin gene, inactive in the K562 leukemic cell, functions normally in a heterologous expression system Proceedings of the National Academy of Sciences of the United States of America. 81: 4485-4489. PMID 6205398 DOI: 10.1073/Pnas.81.14.4485 |
0.411 |
|
| 1984 |
Humphries R, Ley T, Anagnou N, Baur A, Nienhuis A. Beta O-39 thalassemia gene: a premature termination codon causes beta- mRNA deficiency without affecting cytoplasmic beta-mRNA stability Blood. 64: 23-32. DOI: 10.1182/Blood.V64.1.23.Bloodjournal64123 |
0.399 |
|
| 1983 |
Goldsmith ME, Humphries RK, Ley T, Cline A, Kantor JA, Nienhuis AW. "Silent" nucleotide substitution in a beta+-thalassemia globin gene activates splice site in coding sequence RNA. Proceedings of the National Academy of Sciences of the United States of America. 80: 2318-22. PMID 6572978 DOI: 10.1073/Pnas.80.8.2318 |
0.409 |
|
| 1983 |
Young NS, Klein HG, Griffith P, Nienhuis AW. A trial of immunotherapy in aplastic anemia and pure red cell aplasia Journal of Clinical Apheresis. 1: 95-103. PMID 6443216 DOI: 10.1002/Jca.2920010206 |
0.319 |
|
| 1983 |
Ley TJ, Nienhuis AW. A weak upstream promoter gives rise to long human β-globin RNA molecules Biochemical and Biophysical Research Communications. 112: 1041-1048. PMID 6303333 DOI: 10.1016/0006-291X(83)91723-0 |
0.386 |
|
| 1983 |
Greco B, Bielory L, Stephany D, Hsu S, Gascon P, Nienhuis A, Young N. Antithymocyte globulin reacts with many normal human cell types Blood. 62: 1047-1054. DOI: 10.1182/Blood.V62.5.1047.1047 |
0.323 |
|
| 1983 |
Ley T, DeSimone J, Noguchi C, Turner P, Schechter A, Heller P, Nienhuis A. 5-Azacytidine increases gamma-globin synthesis and reduces the proportion of dense cells in patients with sickle cell anemia Blood. 62: 370-380. DOI: 10.1182/Blood.V62.2.370.Bloodjournal622370 |
0.394 |
|
| 1982 |
Chen MJ, Shimada T, Moulton AD, Harrison M, Nienhuis AW. Intronless human dihydrofolate reductase genes are derived from processed RNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 79: 7435-9. PMID 6961421 DOI: 10.1073/Pnas.79.23.7435 |
0.352 |
|
| 1981 |
Farquhar MN, Turner PA, Papayannopoulou T, Brice M, Nienhuis AW, Stamatoyannopoulos G. The asynchrony of gamma- and beta-chain synthesis during human erythroid cell maturation. III. gamma- and beta-mRNA in immature and mature erythroid clones. Developmental Biology. 85: 403-8. PMID 6167478 DOI: 10.1016/0012-1606(81)90271-2 |
0.344 |
|
| 1981 |
Tam JW, Kaufman RE, Nienhuis AW. Analysis of globin gene structure in patients with beta thalassemia by restriction endonuclease mapping. Hemoglobin. 5: 209-15. PMID 6164667 DOI: 10.3109/03630268108997545 |
0.33 |
|
| 1980 |
Yoo D, Schechter GP, Amigable AN, Nienhuis AW. Myeloproliferative syndrome with sideroblastic anemia and acquired hemoglobin H disease Cancer. 45: 78-83. PMID 7351008 DOI: 10.1002/1097-0142(19800101)45:1<78::Aid-Cncr2820450114>3.0.Co;2-N |
0.331 |
|
| 1980 |
Adams JW, Kaufman RE, Kretschmer PJ, Harrison M, Nienhuis AW. A family of long reiterated DNA sequences, one copy of which is next to the human beta globin gene. Nucleic Acids Research. 8: 6113-28. PMID 6258162 DOI: 10.1093/Nar/8.24.6113 |
0.375 |
|
| 1980 |
Kaufman RE, Kretschmer PJ, Adams JW, Coon HC, Anderson WF, Nienhuis AW. Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes. Proceedings of the National Academy of Sciences of the United States of America. 77: 4229-33. PMID 6254016 DOI: 10.1073/Pnas.77.7.4229 |
0.404 |
|
| 1980 |
Nienhuis AW, Barker JE, Croissant RD. Overview: mechanisms of the regulation of hemoglobin synthesis at the cellular level. Annals of the New York Academy of Sciences. 344: 189-205. PMID 6156623 DOI: 10.1111/J.1749-6632.1980.Tb33661.X |
0.384 |
|
| 1980 |
Barker J, Pierce J, Nienhuis A. Hemoglobin switching in sheep: a comparison of the erythropoietin- induced switch to HbC and the fetal to adult hemoglobin switch Blood. 56: 488-494. DOI: 10.1182/Blood.V56.3.488.Bloodjournal563488 |
0.37 |
|
| 1979 |
Willing MC, Nienhuis AW, Anderson WF. Selective activation of human beta-but not gamma-globin gene in human fibroblast x mouse erythroleukaemia cell hybrids. Nature. 277: 534-8. PMID 283312 DOI: 10.1038/277534A0 |
0.432 |
|
| 1978 |
Wilson GN, Streggles AW, Anderson WF, Nienhuis AW. Transcription of chromatin with prokaryotic and eukaryotic polymerases. Methods in Cell Biology. 19: 339-57. PMID 357917 DOI: 10.1016/S0091-679X(08)60034-5 |
0.358 |
|
| 1977 |
Benz E, Turner P, Barker J, Nienhuis A. Stability of the individual globin genes during erythroid differentiation. Science (New York, N.Y.). 196: 1213-4. PMID 860136 DOI: 10.1126/Science.860136 |
0.424 |
|
| 1977 |
Deisseroth A, Nienhuis A, Turner P, Velez R, Anderson WF, Ruddle F, Lawrence J, Creagan R, Kucherlapati R. Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay. Cell. 12: 205-18. PMID 561664 DOI: 10.1016/0092-8674(77)90198-2 |
0.355 |
|
| 1977 |
Nienhuis AW, Benz EJ. Regulation of hemoglobin synthesis during the development of the red cell (first of three parts). The New England Journal of Medicine. 297: 1318-28. PMID 335250 DOI: 10.1056/Nejm197712152972404 |
0.36 |
|
| 1977 |
Barker JE, Pierce JE, Kefauver BC, Nienhuis AW. Hemoglobin switching in sheep and goats: induction of hemoglobin C synthesis in cultures of sheep fetal erythroid cells Proceedings of the National Academy of Sciences of the United States of America. 74: 5078-5082. PMID 270742 DOI: 10.1073/Pnas.74.11.5078 |
0.376 |
|
| 1976 |
Deisseroth A, Velez R, Burk RD, Minna J, Anderson WF, Nienhuis A. Extinction of globin gene expression in human fibroblast × mouse erythroleukemia cell hybrids Somatic Cell Genetics. 2: 373-384. PMID 1071909 DOI: 10.1007/Bf01538841 |
0.45 |
|
| 1976 |
Deisseroth A, Nienhuis A. Study of markers of human erythroid differentiation in hybrid cells. In Vitro Cellular & Developmental Biology – Plant. 12: 734-742. PMID 1071439 DOI: 10.1007/Bf02835448 |
0.433 |
|
| 1976 |
Barker JE, Pierce JE, Nienhuis AW. Hemoglobin switching in sheep and goats. VI. Commitment of erythroid colony forming cells to the synthesis of beta(C) globin Journal of Cell Biology. 71: 715-726. PMID 993267 DOI: 10.1083/Jcb.71.3.715 |
0.347 |
|
| 1976 |
Anderson WF, Deisseroth AB, Velez R, Nienhuis AW, Ruddle FH, Kucherlapati RS. A new technique for mapping the human hemoglobin genes. Cytogenetics and Cell Genetics. 16: 367-71. PMID 975910 DOI: 10.1159/000130634 |
0.305 |
|
| 1975 |
Barker JE, Anderson WF, Nienhuis AW. Hemoglobin switching in sheep and goats. V. Effect of erythropoietin concentration on in vitro erythroid colony growth and globin synthesis Journal of Cell Biology. 64: 515-527. PMID 1171104 DOI: 10.1083/Jcb.64.3.515 |
0.362 |
|
| 1975 |
Anderson WF, Barker JE, Elson NA, Merrick WC, Steggles AW, Wilson GN, Kantor JA, Nienhuis AW. Activation and inactivation of genes determining hemoglobin types Journal of Cellular Physiology. 85: 477-494. PMID 1168204 DOI: 10.1002/Jcp.1040850413 |
0.597 |
|
| 1975 |
Wilson GN, Steggles AW, Nienhuis AW. Strand-selective transcription of globin genes in rabbit erythroid cells and chromatin. Proceedings of the National Academy of Sciences of the United States of America. 72: 4835-4839. PMID 1108006 DOI: 10.1073/Pnas.72.12.4835 |
0.336 |
|
| 1975 |
Deisseroth A, Burk R, Picciano D, Anderson WF, Nienhuis A, Minna JD. Hemoglobin synthesis in somatic cell hybrids: globin gene expression in hybrids between mouse erythroleukemia and human marrow cells or fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 72: 1102-1106. PMID 1055369 DOI: 10.1073/Pnas.72.3.1102 |
0.425 |
|
| 1974 |
Anderson WF, Steggles A, Wilson G, Kantor J, Velez R, Picciano D, Falvey A, Nienhuis A. Cell‐Free Transcription Of Human Bone Marrow Chromatin Annals of the New York Academy of Sciences. 241: 262-273. PMID 4530659 DOI: 10.1111/J.1749-6632.1974.Tb21885.X |
0.304 |
|
| 1974 |
Nienhuis AW, Bunn HF. Hemoglobin switching in sheep and goats: occurrence of hemoglobins A and C in the same red cell. Science. 185: 946-948. PMID 4469671 DOI: 10.1126/Science.185.4155.946 |
0.361 |
|
| 1972 |
Crystal RG, Nienhuis AW, Prichard PM, Picciano D, Elson NA, Merrick WC, Graf H, Shafritz DA, Laycock DG, Last JA, Anderson WF. Initiation of globin synthesis. Febs Letters. 24: 310-314. PMID 11946695 DOI: 10.1016/0014-5793(72)80379-X |
0.39 |
|
| 1971 |
Nienhuis AW, Anderson WF. Isolation and translation of hemoglobin messenger RNA from thalassemia, sickle cell anemia, and normal human reticulocytes. The Journal of Clinical Investigation. 50: 2458-60. PMID 5096528 DOI: 10.1172/Jci106745 |
0.338 |
|
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