Adam S. Duerfeldt
Affiliations: | 2014- | Chemistry & Biochemistry | University of Oklahoma, Norman, OK, United States |
Area:
Medicinal Chemistry, Organic Chemistry, Chemical BiologyGoogle:
"Adam Duerfeldt"Mean distance: 8.24
Parents
Sign in to add mentor| Brian Blagg | grad student | 2006-2011 | University of Kansas | |
| (A New Generation of Hsp90 Inhibitors: Addressing Isoform Selectivity and Heat Shock Induction.) | ||||
| Dale L. Boger | post-doc | 2011-2014 | Scripps Institute | |
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Publications
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| Dou X, Nath D, Shin H, et al. (2020) Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders. Journal of Medicinal Chemistry |
| Li Y, Gardner JJ, Fortney KR, et al. (2019) First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors. Bioorganic & Medicinal Chemistry Letters |
| Lavey NP, Shadid T, Ballard J, et al. (2018) Clostridium difficile ClpP Homologs are Capable of Uncoupled Activity and Exhibit Different Levels of Susceptibility to Acyldepsipeptide Modulation. Acs Infectious Diseases |
| Dou XZ, Nath D, Shin Y, et al. (2018) Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARα selective agonists: New leads for oculovascular conditions. Bioorganic & Medicinal Chemistry Letters |
| Que NLS, Crowley VM, Duerfeldt AS, et al. (2018) Structure based design of a Grp94-selective inhibitor: Exploiting a key residue in Grp94 to optimize paralog-selective binding. Journal of Medicinal Chemistry |
| Li Y, Lavey NP, Coker JA, et al. (2017) Consequences of Depsipeptide Substitution on the ClpP Activation Activity of Antibacterial Acyldepsipeptides. Acs Medicinal Chemistry Letters. 8: 1171-1176 |
| Crowley VM, Khandelwal A, Mishra S, et al. (2016) Development of Glucose Regulated Protein 94-Selective Inhibitors based on the BnIm and Radamide Scaffold. Journal of Medicinal Chemistry |
| Lavey NP, Coker JA, Ruben EA, et al. (2016) Sclerotiamide: The First Non-Peptide-Based Natural Product Activator of Bacterial Caseinolytic Protease P. Journal of Natural Products |
| Di XJ, Wang YJ, Han DY, et al. (2016) Grp94 Delivers γ-aminobutyric Acid Type A (GABAA) Receptors to Hrd1-Mediatd Endoplasmic Reticulum-Associated Degradation. The Journal of Biological Chemistry |
| Anderson ED, Duerfeldt AS, Zhu K, et al. (2014) Cycloadditions of noncomplementary substituted 1,2,3-triazines. Organic Letters. 16: 5084-7 |