Maria Tomasz, Ph.D.

Affiliations: 
1966-2008 Chemistry Hunter College of the City University of New York, New York, NY, United States 
Area:
Drug-DNA interactions
Website:
http://www.hunter.cuny.edu/chemistry/faculty/Maria/Maria
Google:
"Maria Tomasz"
Mean distance: 7.5
 
SNBCP

Parents

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Gilbert Stork grad student 1959-1962 Columbia
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Publications

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Bargonetti J, Champeil E, Tomasz M. (2010) Differential toxicity of DNA adducts of mitomycin C. Journal of Nucleic Acids. 2010
Weng MW, Zheng Y, Jasti VP, et al. (2010) Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model. Nucleic Acids Research. 38: 6976-84
Boamah EK, Brekman A, Tomasz M, et al. (2010) DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1. Chemical Research in Toxicology. 23: 1151-62
Shen X, Do H, Li Y, et al. (2009) Recruitment of Fanconi Anemia and Breast Cancer Proteins to DNA Damage Sites Is Differentially Governed by Replication Molecular Cell. 35: 716-723
Paz MM, Ladwa S, Champeil E, et al. (2008) Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry. Chemical Research in Toxicology. 21: 2370-8
Champeil E, Paz MM, Ladwa S, et al. (2008) Synthesis of an oligodeoxyribonucleotide adduct of mitomycin C by the postoligomerization method via a triamino mitosene. Journal of the American Chemical Society. 130: 9556-65
Boamah EK, White DE, Talbott KE, et al. (2007) Mitomycin-DNA adducts induce p53-dependent and p53-independent cell death pathways. Acs Chemical Biology. 2: 399-407
Utzat CD, Clement CC, Ramos LA, et al. (2005) DNA adduct of the mitomycin C metabolite 2,7-diaminomitosene is a nontoxic and nonmutagenic DNA lesion in vitro and in vivo. Chemical Research in Toxicology. 18: 213-23
Seow HA, Belcourt MF, Penketh PG, et al. (2005) Nuclear localization of NADPH:cytochrome c (P450) reductase enhances the cytotoxicity of mitomycin C to Chinese hamster ovary cells. Molecular Pharmacology. 67: 417-23
Paz MM, Kumar GS, Glover M, et al. (2004) Mitomycin dimers: polyfunctional cross-linkers of DNA. Journal of Medicinal Chemistry. 47: 3308-19
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