Nathan Elliott Fishkin

Affiliations: 
2004 Columbia University, New York, NY 
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"Nathan Fishkin"
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Koji Nakanishi grad student 2004 Columbia
 (Bioorganic studies of rhodopsin and the visual cycle.)
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Publications

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Reid EE, Archer KE, Shizuka M, et al. (2019) Effect of Linker Stereochemistry on the Activity of Indolinobenzodiazepine Containing Antibody-Drug Conjugates (ADCs). Acs Medicinal Chemistry Letters. 10: 1193-1197
Miller ML, Fishkin NE, Li W, et al. (2016) A New Class of Antibody-Drug Conjugates with Potent DNA Alkylating Activity. Molecular Cancer Therapeutics
Singh R, Setiady YY, Ponte J, et al. (2016) A new, triglycyl peptide linker for antibody-drug conjugates (ADCs) with improved targeted killing of cancer cells. Molecular Cancer Therapeutics
Ponte JF, Sun X, Yoder NC, et al. (2016) Understanding How the Stability of the Thiol-Maleimide Linkage Impacts the Pharmacokinetics of Lysine-linked Antibody-Maytansinoid Conjugates. Bioconjugate Chemistry
Harris L, Lanieri L, Ponte J, et al. (2016) Abstract 2967:In vitroandin vivoactivity of site-specific antibody-drug conjugates (ADCs) with 2 and 4 maytansinoid molecules per antibody prepared through conjugation to SeriMabs (N-terminal serine engineered Abs) Cancer Research. 76: 2967-2967
Vitharana D, Wilhelm A, Harris L, et al. (2016) Abstract 2965:In vitroandin vivoactivity of a site-specific SeriMab antibody-drug conjugate (ADC) using an indolino-benzodiazepine DNA-alkylating agent Cancer Research. 76: 2965-2965
Widdison WC, Ponte JF, Coccia JA, et al. (2015) Development of anilino-maytansinoid ADCs that efficiently release cytotoxic metabolites in cancer cells and induce high levels of bystander killing. Bioconjugate Chemistry
Tavares D, Rui L, Ab O, et al. (2015) Abstract 653: Antibody-drug conjugates: engineered N-terminal serine residues as a novel approach for site-specific conjugation Cancer Research. 75: 653-653
Miller ML, Shizuka M, Fishkin N, et al. (2015) Abstract 652: Antibody-drug conjugates (ADCs) of indolino-benzodiazepine DNA-alkylating agents Cancer Research. 75: 652-652
Harris L, Tavares D, Rui L, et al. (2015) Abstract 647: SeriMabs: N-terminal serine modification enables modular, site-specific payload incorporation into antibody-drug conjugates (ADCs) Cancer Research. 75: 647-647
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