Tiffany Nicole Heady
Affiliations: | 2001 | University of Virginia, Charlottesville, VA |
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Parents
Sign in to add mentor| Timothy L. Macdonald | grad student | 2001 | UVA | |
| (Design and synthesis of novel calcium influx inhibitors: Work towards a cytostatic cancer therapy.) | ||||
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Publications
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| Lee PJ, Bhonsle JB, Gaona HW, et al. (2009) Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents. Journal of Medicinal Chemistry. 52: 952-63 |
| Dow GS, Heady TN, Bhattacharjee AK, et al. (2006) Utility of alkylaminoquinolinyl methanols as new antimalarial drugs. Antimicrobial Agents and Chemotherapy. 50: 4132-43 |
| McCalmont WF, Patterson JR, Lindenmuth MA, et al. (2005) Investigation into the structure-activity relationship of novel concentration dependent, dual action T-type calcium channel agonists/antagonists. Bioorganic & Medicinal Chemistry. 13: 3821-39 |
| Gray L, Perez-Reyes E, Gomora J, et al. (2005) Erratum to “The role of voltage gated T-type Ca2+ channel isoforms in mediating “capacitative” Ca2+ entry in cancer cells” [Cell Calcium 36 (2004) 489–497] Cell Calcium. 37: 603 |
| Gray LS, Perez-Reyes E, Gomora JC, et al. (2004) The role of voltage gated T-type Ca2+ channel isoforms in mediating "capacitative" Ca2+ entry in cancer cells. Cell Calcium. 36: 489-97 |
| McCalmont WF, Heady TN, Patterson JR, et al. (2004) Design, synthesis, and biological evaluation of novel T-Type calcium channel antagonists. Bioorganic & Medicinal Chemistry Letters. 14: 3691-5 |
| Smith KS, Smith PL, Heady TN, et al. (2003) In vitro metabolism of tolcapone to reactive intermediates: relevance to tolcapone liver toxicity. Chemical Research in Toxicology. 16: 123-8 |
| Heady TN, Gomora JC, Macdonald TL, et al. (2001) Molecular pharmacology of T-type Ca2+ channels. Japanese Journal of Pharmacology. 85: 339-50 |
| Haverstick DM, Heady TN, Macdonald TL, et al. (2000) Inhibition of human prostate cancer proliferation in vitro and in a mouse model by a compound synthesized to block Ca2+ entry. Cancer Research. 60: 1002-8 |