Ran Zhu, Ph.D.
Institution:
University of Virginia, Charlottesville, VAArea:
Bioorganic and Synthetic Organic ChemistryGoogle:
"Ran Zhu"Mean distance: 8.25
Parents
Sign in to add mentor| Timothy L. Macdonald | grad student | 2008 | UVA | |
| (Synthesis and biological evaluation of conformationally constrained sphingosine -1 -phosphate analogs as subtype selective S1P receptor agonist/antagonist.) | ||||
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Publications
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| Kennedy PC, Zhu R, Huang T, et al. (2011) Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. The Journal of Pharmacology and Experimental Therapeutics. 338: 879-89 |
| Sun Q, Zhu R, Foss FW, et al. (2008) In vitro metabolism of a model cyclopropylamine to reactive intermediate: Insights into trovafloxacin-induced hepatotoxicity Chemical Research in Toxicology. 21: 711-719 |
| Zhu R, Snyder AH, Kharel Y, et al. (2007) Asymmetric synthesis of conformationally constrained fingolimod analogues--discovery of an orally active sphingosine 1-phosphate receptor type-1 agonist and receptor type-3 antagonist. Journal of Medicinal Chemistry. 50: 6428-35 |
| Sun Q, Zhu R, Foss FW, et al. (2007) Mechanisms of trovafloxacin hepatotoxicity: Studies of a model cyclopropylamine-containing system Bioorganic and Medicinal Chemistry Letters. 17: 6682-6686 |
| Zhu R, Frazier CR, Linden J, et al. (2006) N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists. Bioorganic & Medicinal Chemistry Letters. 16: 2416-8 |
| Kharel Y, Lee S, Snyder AH, et al. (2005) Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720. The Journal of Biological Chemistry. 280: 36865-72 |