James E. East, Ph.D.

University of Virginia, Charlottesville, VA 
Bioorganic and Synthetic Organic Chemistry
"James East"
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Timothy L. Macdonald grad student 2011 UVA
 (Small Molecule Modulation of the Lysophosphatidic Acid Pathway.)
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Sun W, Wang Y, East JE, et al. (2015) Invariant natural killer T cells generated from human adult hematopoietic stem-progenitor cells are poly-functional. Cytokine. 72: 48-57
Suffredini G, East JE, Levy LM. (2014) New applications of nanotechnology for neuroimaging. Ajnr. American Journal of Neuroradiology. 35: 1246-53
East JE, Kennedy AJ, Webb TJ. (2014) Raising the roof: the preferential pharmacological stimulation of Th1 and th2 responses mediated by NKT cells. Medicinal Research Reviews. 34: 45-76
Subrahmanyam PB, Sun W, East JE, et al. (2012) Natural killer T cell based Immunotherapy. Journal of Vaccines & Vaccination. 3: 144
East JE, Sun W, Webb TJ. (2012) Artificial antigen presenting cell (aAPC) mediated activation and expansion of natural killer T cells. Journal of Visualized Experiments : Jove
East JE, Macdonald TL. (2012) Cost-effective and Large-scale synthesis of 16:0 Lysophosphatidic Acid. Synthetic Communications. 42: 3614-3618
Sun W, Subrahmanyam PB, East JE, et al. (2012) Connecting the dots: artificial antigen presenting cell-mediated modulation of natural killer T cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 32: 505-16
East JE, MacDonald TL. (2012) Cost-effective and large-scale synthesis of 16:0 lysophosphatidic acid Synthetic Communications. 42: 3614-3619
East JE, Carter KM, Kennedy PC, et al. (2011) Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist. Medchemcomm. 2: 325-330
Kennedy AJ, Mathews TP, Kharel Y, et al. (2011) Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells. Journal of Medicinal Chemistry. 54: 3524-48
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