James Surapisitchat, Ph.D.

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
control of signal transduction by cyclic nucleotide second messengers in the cell
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"James Surapisitchat"
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Joseph A. Beavo grad student 2007 University of Washington
 (Differential regulation of endothelial cell permeability by cGMP via phosphodiesterase 2A and phosphodiesterase 3A.)
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Publications

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Surapisitchat J, Beavo JA. (2011) Regulation of endothelial barrier function by cyclic nucleotides: the role of phosphodiesterases. Handbook of Experimental Pharmacology. 193-210
Surapisitchat J, Beavo JA. (2011) Phosphodiesterase 11 Xpharm: the Comprehensive Pharmacology Reference. 1-10
Surapisitchat J, Beavo JA. (2010) Phosphodiesterase Families Handbook of Cell Signaling, 2/E. 2: 1409-1414
Beavo JA, Surapisitchat J, Parchen C. (2009) Cyclic nucleotide phosphodiesterases – 40 years of progress Bmc Pharmacology. 9
Li L, Tatake RJ, Natarajan K, et al. (2008) Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochemical and Biophysical Research Communications. 370: 159-63
Surapisitchat J, Jeon KI, Yan C, et al. (2007) Differential regulation of endothelial cell permeability by cGMP via phosphodiesterases 2 and 3. Circulation Research. 101: 811-8
Lerner-Marmarosh N, Yoshizumi M, Che W, et al. (2003) Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1775-81
Berk BC, Min W, Yan C, et al. (2002) Atheroprotective Mechanisms Activated by Fluid Shear Stress in Endothelial Cells. Drug News & Perspectives. 15: 133-139
Berk BC, Abe JI, Min W, et al. (2001) Endothelial atheroprotective and anti-inflammatory mechanisms. Annals of the New York Academy of Sciences. 947: 93-109; discussion 1
Surapisitchat J, Hoefen RJ, Pi X, et al. (2001) Fluid shear stress inhibits TNF-alpha activation of JNK but not ERK1/2 or p38 in human umbilical vein endothelial cells: Inhibitory crosstalk among MAPK family members. Proceedings of the National Academy of Sciences of the United States of America. 98: 6476-81
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