Edward Geisinger, Ph.D.

Basic Medical Science New York University, New York, NY, United States 
Staphylococcus aureus; superantigens; mobile genes; pathogenicity islands, signal transduction, regulation of virulence, microbial pathogenesis; MRSA; bacterial genetics
"Edward Geisinger"
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Richard Novick grad student 2008 NYU
 (Studies on the molecular mechanisms of Staphylococcal quorum sensing.)
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Brown A, Raustad N, Geisinger E. (2022) Outer Membrane Regulation in Acinetobacter: Controlling the Shield against Antibiotics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Hernandez G, Raustad N, Iinishi A, et al. (2022) How Acinetobacter baumanniiControls Antibiotic Resistance through Phosphorylation of the BfmR Global Regulator. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Bai J, Dai Y, Farinha A, et al. (2021) Essential gene analysis in by high-density transposon mutagenesis and CRISPR interference. Journal of Bacteriology
Geisinger E, Mortman NJ, Dai Y, et al. (2020) Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope. Nature Communications. 11: 4522
Geisinger E, Vargas-Cuebas G, Mortman NJ, et al. (2019) The Landscape of Phenotypic and Transcriptional Responses to Ciprofloxacin in Acinetobacter baumannii: Acquired Resistance Alleles Modulate Drug-Induced SOS Response and Prophage Replication. Mbio. 10
Geisinger E, Mortman NJ, Vargas-Cuebas G, et al. (2018) A global regulatory system links virulence and antibiotic resistance to envelope homeostasis in Acinetobacter baumannii. Plos Pathogens. 14: e1007030
Geisinger E, Isberg RR. (2017) Interplay Between Antibiotic Resistance and Virulence During Disease Promoted by Multidrug-Resistant Bacteria. The Journal of Infectious Diseases. 215: S9-S17
Geisinger E, Isberg RR. (2015) Antibiotic modulation of capsular exopolysaccharide and virulence in Acinetobacter baumannii. Plos Pathogens. 11: e1004691
Geisinger E, Chen J, Novick RP. (2012) Allele-dependent differences in quorum-sensing dynamics result in variant expression of virulence genes in Staphylococcus aureus. Journal of Bacteriology. 194: 2854-64
Geisinger E, George EA, Chen J, et al. (2012) Identification of ligand specificity determinants in AgrC, the Staphylococcus aureus quorum-sensing receptor (Journal of Biological Chemistry (2012) 283, (8930-8938)) Journal of Biological Chemistry. 287: 18588
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