Michael E. Schaffer, Ph.D.

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Cancer Research
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"Michael Schaffer"
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Geoffrey M. Cooper grad student 2007 Boston University
 (Elucidation of human growth factor mediated transcriptional programs and computational inference of their regulation.)
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Publications

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Schaffner F, Yokota N, Carneiro-Lobo T, et al. (2013) Endothelial Protein C Receptor Function in Murine and Human Breast Cancer Development Plos One. 8
Caffrey DR, Zhao J, Song Z, et al. (2011) siRNA off-target effects can be reduced at concentrations that match their individual potency. Plos One. 6: e21503
Terragni J, Graham JR, Adams KW, et al. (2008) Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors. Bmc Cell Biology. 9: 6
Tullai JW, Schaffer ME, Mullenbrock S, et al. (2007) Immediate-early and delayed primary response genes are distinct in function and genomic architecture. The Journal of Biological Chemistry. 282: 23981-95
O'Lone R, Knorr K, Jaffe IZ, et al. (2007) Estrogen receptors alpha and beta mediate distinct pathways of vascular gene expression, including genes involved in mitochondrial electron transport and generation of reactive oxygen species. Molecular Endocrinology (Baltimore, Md.). 21: 1281-96
Tullai JW, Chen J, Schaffer ME, et al. (2007) Glycogen synthase kinase-3 represses cyclic AMP response element-binding protein (CREB)-targeted immediate early genes in quiescent cells. The Journal of Biological Chemistry. 282: 9482-91
Tullai JW, Schaffer ME, Mullenbrock S, et al. (2004) Identification of transcription factor binding sites upstream of human genes regulated by the phosphatidylinositol 3-kinase and MEK/ERK signaling pathways. The Journal of Biological Chemistry. 279: 20167-77
Su Y, Murali TM, Pavlovic V, et al. (2003) RankGene: Identification of diagnostic genes based on expression data Bioinformatics. 19: 1578-1579
Boucher DM, Schäffer M, Deissler K, et al. (2000) goosecoid expression represses Brachyury in embryonic stem cells and affects craniofacial development in chimeric mice. The International Journal of Developmental Biology. 44: 279-88
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