Brooks E. Taylor, Ph.D.

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
signaling, transcription, computational network; stress and immune responses, apoptosis, proliferation
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"Brooks Taylor"
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Alexander Hoffmann grad student 2015 UCSD
 (Single-cell NF-kappaB signaling in macrophages.)
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Publications

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Luecke S, Adelaja A, Guo X, et al. (2023) Tonic TNF conditioning of macrophages safeguards stimulus-specific inflammatory responses. Embo Reports. e55986
Cheng QJ, Ohta S, Sheu KM, et al. (2021) NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages. Science (New York, N.Y.). 372: 1349-1353
Adelaja A, Taylor B, Sheu KM, et al. (2021) Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses. Immunity. 54: 916-930.e7
Oliver Metzig M, Tang Y, Mitchell S, et al. (2020) An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions. Molecular Systems Biology. 16: e9677
Taylor B, Shah A, Bielczyk-Maczyńska E. (2020) TGF-β is insufficient to induce adipocyte state loss without concurrent PPARγ downregulation. Scientific Reports. 10: 14084
Kovary KM, Taylor B, Zhao ML, et al. (2018) Expression variation and covariation impair analog and enable binary signaling control. Molecular Systems Biology. 14
Cheng Z, Taylor B, Ourthiague DR, et al. (2015) Distinct single-cell signaling characteristics are conferred by the MyD88 and TRIF pathways during TLR4 activation. Science Signaling. 8: ra69
Selimkhanov J, Taylor B, Yao J, et al. (2014) Systems biology. Accurate information transmission through dynamic biochemical signaling networks. Science (New York, N.Y.). 346: 1370-3
Bass GT, Ryall KA, Katikapalli A, et al. (2012) Automated image analysis identifies signaling pathways regulating distinct signatures of cardiac myocyte hypertrophy. Journal of Molecular and Cellular Cardiology. 52: 923-30
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