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Fraser A. Hof, Ph.D.

Affiliations: 
1998-2003 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2005- Chemistry University of Victoria, Victoria, British Columbia, Canada 
Area:
molecular recognition and self-assembling systems
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"Fraser Hof"
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Parents

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Julius Rebek, Jr. grad student 2003 Scripps Institute
 (Self -assembled tetrameric capsules.)
François N. Diederich post-doc 2003-2005 ETH Zürich

Children

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Natasha Helen Milosevich grad student 2013- University of Victoria (Theology Tree)
Alok Shaurya grad student 2013- University of Victoria (Theology Tree)
Meagan Beatty grad student 2014- University of Victoria (Theology Tree)
Amanda L. Whiting grad student 2012 University of Victoria
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Publications

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Hof F. (2016) Host–guest chemistry that directly targets lysine methylation: synthetic host molecules as alternatives to bio-reagents Chemical Communications. 52: 10093-10108
Hobbs JK, Lee SM, Robb M, et al. (2016) KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America
Garnett GA, Starke MJ, Shaurya A, et al. (2016) Supramolecular Affinity Chromatography for Methylation-Targeted Proteomics. Analytical Chemistry. 88: 3697-703
Garnett GA, Daze KD, Peña Diaz JA, et al. (2016) Attraction by repulsion: compounds with like charges undergo self-assembly in water that improves in high salt and persists in real biological fluids. Chemical Communications (Cambridge, England)
Ali M, Daze KD, Strongin DE, et al. (2015) Molecular insight into inhibition of the methylated histone-plant homeodomain complexes by calixarenes. The Journal of Biological Chemistry
McGovern RE, Snarr BD, Lyons JA, et al. (2015) Structural study of a small molecule receptor bound to dimethyllysine in lysozyme. Chemical Science (Royal Society of Chemistry : 2010). 6: 442-449
Wu J, Li W, Hajisalem G, et al. (2014) Trace cancer biomarker quantification using polystyrene-functionalized gold nanorods. Biomedical Optics Express. 5: 4101-7
Simhadri C, Daze KD, Douglas SF, et al. (2014) Chromodomain antagonists that target the polycomb-group methyllysine reader protein chromobox homolog 7 (CBX7). Journal of Medicinal Chemistry. 57: 2874-83
Allen HF, Daze KD, Shimbo T, et al. (2014) Inhibition of histone binding by supramolecular hosts. The Biochemical Journal. 459: 505-12
Tabet S, Douglas SF, Daze KD, et al. (2013) Synthetic trimethyllysine receptors that bind histone 3, trimethyllysine 27 (H3K27me3) and disrupt its interaction with the epigenetic reader protein CBX7. Bioorganic & Medicinal Chemistry. 21: 7004-10
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