Gabriel S. Brandt, Ph.D.
Affiliations: | Chemistry | Franklin & Marshall College, Lancaster, PA, United States | |
| 2003 | California Institute of Technology, Pasadena, CA |
Area:
physical organic chemistry to systems of biological importanceWebsite:
https://www.fandm.edu/gabriel-brandtGoogle:
"Gabriel S. Brandt"Bio:
Brandt, Gabriel Shaw Site-specific incorporation of synthetic amino acids into functioning ion channels. Dissertation (Ph.D.), California Institute of Technology (2003).
http://www.bio.brandeis.edu/prLab/formerMembers.html
Mean distance: 8.21 | S | N | B | C | P |
Parents
Sign in to add mentor| Dennis A. Dougherty | grad student | 2003 | Caltech | |
| (Site-specific incorporation of synthetic amino acids into functioning ion channels.) | ||||
| Gregory A. Petsko | post-doc | 2008 | Brandeis | |
| Dagmar Ringe | post-doc | 2008 | Brandeis | |
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Publications
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| Liu CF, Brandt GS, Hoang QQ, et al. (2016) Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proceedings of the National Academy of Sciences of the United States of America. 113: E6572-E6581 |
| Naffin-Olivos JL, Georgieva M, Goldfarb N, et al. (2014) Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2. Plos Pathogens. 10: e1004132 |
| Brandt GS, Kneen MM, Petsko GA, et al. (2010) Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition Journal of the American Chemical Society. 132: 438-439 |
| Brandt GS, Kneen MM, Chakraborty S, et al. (2009) Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor. Biochemistry. 48: 3247-57 |
| Chakraborty S, Nemeria NS, Balakrishnan A, et al. (2009) Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry. 48: 981-94 |
| Brandt GS, Nemeria N, Chakraborty S, et al. (2008) Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester. Biochemistry. 47: 7734-43 |
| Rothman DM, Petersson EJ, Vázquez ME, et al. (2005) Caged phosphoproteins. Journal of the American Chemical Society. 127: 846-7 |
| Petersson EJ, Brandt GS, Zacharias NM, et al. (2003) Caging proteins through unnatural amino acid mutagenesis. Methods in Enzymology. 360: 258-73 |
| Beene DL, Brandt GS, Zhong W, et al. (2002) Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine. Biochemistry. 41: 10262-9 |
| Philipson KD, Gallivan JP, Brandt GS, et al. (2001) Incorporation of caged cysteine and caged tyrosine into a transmembrane segment of the nicotinic ACh receptor. American Journal of Physiology. Cell Physiology. 281: C195-206 |