Natalie A. Hawryluk, Ph.D.

Affiliations: 
2001 Brandeis University, Waltham, MA, United States 
Area:
synthetic organic chemistry
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Barry B. Snider grad student 2001 Brandeis
 (Total synthesis of (-)-dysiherbaine alcohol inversion using cesium carboxylates and DMAP in toluene synthesis of the functionalized core of guanacastepene.)
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Letavic MA, Lord B, Bischoff F, et al. (2013) Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists. Acs Medicinal Chemistry Letters. 4: 419-22
Hawryluk NA, Merit JE, Lebsack AD, et al. (2010) Discovery and synthesis of 6,7,8,9-tetrahydro-5H-pyrimido-[4,5-d]azepines as novel TRPV1 antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 7137-41
Lebsack AD, Rech JC, Branstetter BJ, et al. (2010) 1,2-diamino-ethane-substituted-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepines as TRPV1 antagonists with improved properties. Bioorganic & Medicinal Chemistry Letters. 20: 7142-6
Lou Y, Horikawa M, Kloster RA, et al. (2004) A new chiral Rh(II) catalyst for enantioselective [2 + 1]-cycloaddition. mechanistic implications and applications. Journal of the American Chemical Society. 126: 8916-8
Shi B, Hawryluk NA, Snider BB. (2003) Formal synthesis of (+/-)-guanacastepene A. The Journal of Organic Chemistry. 68: 1030-42
Eggler JF, Gabel CA, Zandi K, et al. (2002) Synthesis of covalent [14C]-labeled diarylsulfonylurea (DASU) inhibitors of the processing and release of IL-1 Journal of Labelled Compounds and Radiopharmaceuticals. 45: 785-794
Corbin PS, Zimmerman SC, Thiessen PA, et al. (2001) Complexation-induced unfolding of heterocyclic ureas. Simple foldamers equilibrate with multiply hydrogen-bonded sheetlike structures. Journal of the American Chemical Society. 123: 10475-88
Snider BB, Hawryluk NA. (2001) Synthesis of the hydroazulene ring system of guanacastepene. Organic Letters. 3: 569-72
Hawryluk NA, Snider BB. (2000) Alcohol inversion using cesium carboxylates and DMAP in toluene. The Journal of Organic Chemistry. 65: 8379-80
Snider BB, Hawryluk NA. (2000) Synthesis of (-)-dysiherbaine. Organic Letters. 2: 635-8
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