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Shenlin Huang, Ph.D.

Affiliations: 
2011 Chemistry University of California, Santa Barbara, Santa Barbara, CA, United States 
Area:
Organometallic chemistry
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"Shenlin Huang"
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Bruce H. Lipshutz grad student 2011 UC Santa Barbara
 (I. Copper Chemistry in Water at Room Temperature II. Aryl Carbon-Hydrogen Functionalization at Room Temperature III. Atroposelective Syntheses of Axially Chiral Biaryls.)

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Publications

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Fu Y, Liang H, Lu Y, et al. (2024) Photoredox-Enabled Deconstructive [5 + 1] Annulation Approach to Isoquinolones from Indanones in Water. Organic Letters
He T, Liang C, Cheng H, et al. (2024) Cathodically Coupled Electrolysis to Access Biheteroaryls. Organic Letters. 26: 607-612
Ramurthy S, Taft BR, Aversa RJ, et al. (2019) Design and Discovery of N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (LXH254)- A selective, efficacious and well-tolerated RAF inhibitor targeting RAS mutant cancers: The path to the clinic. Journal of Medicinal Chemistry
Feng Q, Chen D, Hong M, et al. (2018) Phenyliodine(III) Bis(trifluoroacetate) (PIFA)-Mediated Synthesis of Aryl Sulfides in Water. The Journal of Organic Chemistry
Nishiguchi GA, Rico A, Tanner HR, et al. (2017) Design and Discovery of N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A potent, selective and efficacious RAF inhibitor targeting RAS mutant cancers. Journal of Medicinal Chemistry
Nishikata T, Abela AR, Huang S, et al. (2016) Cationic Pd(II)-catalyzed C-H activation/cross-coupling reactions at room temperature: synthetic and mechanistic studies. Beilstein Journal of Organic Chemistry. 12: 1040-64
Lipshutz BH, Huang S, Leong WW, et al. (2012) C-C bond formation via copper-catalyzed conjugate addition reactions to enones in water at room temperature. Journal of the American Chemical Society. 134: 19985-8
Huang S, Petersen TB, Lipshutz BH. (2010) Total synthesis of (+)-korupensamine B via an atropselective intermolecular biaryl coupling. Journal of the American Chemical Society. 132: 14021-3
Nishikata T, Abela AR, Huang S, et al. (2010) Cationic palladium(II) catalysis: C-H activation/Suzuki-Miyaura couplings at room temperature. Journal of the American Chemical Society. 132: 4978-9
Lipshutz B, Huang S, Petersen T. (2010) Atropselective Biaryl Coupling in the Synthesis of (+)-Korupensamine B Synfacts. 2010: 1395-1395
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