Seth M. Rubin
Affiliations: | Chemistry & Biochemistry | University of California, Santa Cruz, Santa Cruz, CA, United States |
Area:
Molecular Mechanisms of Cell Cycle Regulation and CancerWebsite:
http://www.chemistry.ucsc.edu/faculty/singleton.php?&singleton=true&cruz_id=srubinGoogle:
"Seth Michael Rubin"Bio:
http://rubin.chemistry.ucsc.edu//RubinLab/Home.html
http://news.ucsc.edu/2008/06/2291.html
http://www.pewtrusts.org/en/projects/pew-biomedical-scholars/directory-of-pew-scholars/2008/seth-rubin
Mean distance: (not calculated yet) (cluster 18) | S | N | B | C | P |
Cross-listing: Cell Biology Tree - DevTree
Parents
Sign in to add mentor| David E. Wemmer | grad student | 1998-2003 | UC Berkeley | |
| (Characterization and application of xenon-protein interactions by nuclear magnetic resonance spectroscopy) | ||||
| Nikola P. Pavletich | post-doc | Memorial Sloan-Kettering Cancer Center | ||
Children
Sign in to add trainee| Anushweta Asthana | grad student | UC Santa Cruz | |
| Eva Rose Balog | grad student | 2012 | UC Santa Cruz (Cell Biology Tree) |
| Jason R. Burke | grad student | 2012 | UC Santa Cruz (Cell Biology Tree) |
| Christopher Joseph Smyrniotis | grad student | 2014 | UC Santa Cruz (Cell Biology Tree) |
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Publications
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| Castro A, Ruiz-Rivera A, Moorman CC, et al. (2025) Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein (Rb) pocket domain. The Journal of Biological Chemistry. 108284 |
| Ngoi P, Wang X, Putta S, et al. (2025) Structural mechanism for recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F. Biorxiv : the Preprint Server For Biology |
| Putta S, Villegas CA, Rubin SM. (2025) Differences in binding affinity among cell-cycle CDK and cyclin pairs. Journal of Molecular Biology. 168952 |
| Hammond T, Choi JB, Membreño MW, et al. (2024) THE FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle. Biorxiv : the Preprint Server For Biology |
| Tambo CS, Tripathi S, Perera BGK, et al. (2023) Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. Acs Chemical Biology |
| Wijeratne TU, Guiley KZ, Lee HW, et al. (2022) Cyclin-dependent kinase-mediated phosphorylation and the negative regulatory domain of transcription factor B-Myb modulate its DNA binding. The Journal of Biological Chemistry. 102319 |
| Putta S, Alvarez L, Lüdtke S, et al. (2022) Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family. Structure (London, England : 1993) |
| Müller GA, Asthana A, Rubin SM. (2022) Structure and function of MuvB complexes. Oncogene |
| Asthana A, Ramanan P, Hirschi A, et al. (2022) The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes. Nature Communications. 13: 526 |
| Enrico TP, Stallaert W, Wick ET, et al. (2021) Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2. Elife. 10 |