Case W. McNamara, Ph.D.

Affiliations: 
2006 University of California, San Diego, La Jolla, CA 
Area:
Mechanisms of bacterial and protozoan pathogenesis, and host response against infectious microbes
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Parents

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Partho Ghosh grad student 2006 UCSD
 (Molecular analysis of Streptococcus pyogenes M1 protein.)
Elizabeth Ann Winzeler post-doc 2007-2012 Genomics Institute of the Novartis Research Foundation
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Publications

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Godinez-Macias KP, Chen D, Wallis JL, et al. (2025) Revisiting the druggable genome using predicted structures and data mining. Npj Drug Discovery. 2: 3
Uddin T, Xia J, Fu Y, et al. (2025) High-Throughput Repurposing Screen Reveals Compounds with Activity against Bradyzoites. Acs Infectious Diseases
Godinez-Macias KP, Chen D, Wallis JL, et al. (2024) Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining. Research Square
Luth MR, Godinez-Macias KP, Chen D, et al. (2024) Systematic in vitro evolution in reveals key determinants of drug resistance. Science (New York, N.Y.). 386: eadk9893
Rouch CC, Chatterjee AK, McCarty C, et al. (2024) Synthesis and Structure-Activity relationship of covalent inhibitors of SARS-CoV-2 papain-like protease with antiviral potency. Bioorganic & Medicinal Chemistry Letters. 130034
Uddin T, Xia J, Fu Y, et al. (2024) High Throughput Repurposing Screen Reveals Compounds with Activity Against Bradyzoites. Biorxiv : the Preprint Server For Biology
Mogire RM, Miruka SA, Juma DW, et al. (2024) Protein target similarity is positive predictor of in vitro antipathogenic activity: a drug repurposing strategy for Plasmodium falciparum. Journal of Cheminformatics. 16: 63
Hasan MM, Mattice EB, Teixeira JE, et al. (2024) Cryptosporidium life cycle small molecule probing implicates translational repression and an Apetala 2 transcription factor in macrogamont differentiation. Plos Pathogens. 20: e1011906
Carucci M, Duez J, Tarning J, et al. (2023) Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nature Communications. 14: 1951
Maher SP, Bakowski MA, Vantaux A, et al. (2023) A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Hypnozoites. Biorxiv : the Preprint Server For Biology
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