Matthew G. McDonald, Ph.D.
Affiliations: | 2001 | University of Washington, Seattle, Seattle, WA |
Area:
biosynthesis of antibiotics and related natural productsGoogle:
"Matthew McDonald"Mean distance: 9.22
Parents
Sign in to add mentor| Heinz G. Floss | grad student | 2001 | University of Washington | |
| (Biosynthetic studies on phenazine antibiotics.) | ||||
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Publications
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| McDonald MG, Tian DD, Thummel KE, et al. (2020) Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| McDonald MG, Henderson LM, Ray S, et al. (2020) Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People. The Journal of Pharmacology and Experimental Therapeutics |
| Kowalski JP, McDonald MG, Pelletier RD, et al. (2020) Design and Characterization of the First Selective and Potent Mechanism-Based Inhibitor of Cytochrome P450 4Z1. Journal of Medicinal Chemistry |
| Kowalski JP, McDonald MG, Whittington D, et al. (2019) Structure-Activity Relationships for CYP4B1 Bioactivation of 4-Ipomeanol Congeners: Direct Correlation between Cytotoxicity and Trapped Reactive Intermediates. Chemical Research in Toxicology |
| McDonald MG, Yeung CK, Teitelbaum AM, et al. (2019) A New LC-MS Assay for the Quantitative Analysis of Vitamin K Metabolites in Human Urine. Journal of Lipid Research |
| Teitelbaum AM, McDonald MG, Kowalski JP, et al. (2018) Influence of Stereochemistry on the Bioactivation and Glucuronidation of 4-Ipomeanol. The Journal of Pharmacology and Experimental Therapeutics |
| McDonald MG, Ray S, Amorosi CJ, et al. (2017) Expression and functional characterization of breast cancer-associated cytochrome P450 4Z1 in Saccharomyces cerevisiae. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| Shirasaka Y, Chaudhry AS, McDonald M, et al. (2015) Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content. The Pharmacogenomics Journal |
| McDonald MG, Au NT, Rettie AE. (2015) P450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory Mechanisms. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 1661-9 |
| Marsillach J, Suzuki SM, Richter RJ, et al. (2014) Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase. Plos One. 9: e110054 |