Stephanie L. Gantt, Ph.D.
Affiliations: | 2006 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Enzymology, metalloenzymes, ribozyme, RNAGoogle:
"Stephanie Gantt"Mean distance: 8.71 | S | N | B | C | P |
Parents
Sign in to add mentor| Carol A. Fierke | grad student | 2006 | University of Michigan | |
| (Human histone deacetylase 8: Metal dependence and catalytic mechanism.) | ||||
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Publications
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| Gantt SL, Joseph CG, Fierke CA. (2010) Activation and inhibition of histone deacetylase 8 by monovalent cations. The Journal of Biological Chemistry. 285: 6036-43 |
| Dowling DP, Gantt SL, Gattis SG, et al. (2008) Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry. 47: 13554-63 |
| Gantt SL, Gattis SG, Fierke CA. (2006) Catalytic activity and inhibition of human histone deacetylase 8 is dependent on the identity of the active site metal ion. Biochemistry. 45: 6170-8 |
| Pirrung MC, Tumey LN, Raetz CR, et al. (2002) Inhibition of the antibacterial target UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC): isoxazoline zinc amidase inhibitors bearing diverse metal binding groups. Journal of Medicinal Chemistry. 45: 4359-70 |