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Kaizhang He, Ph.D.

Affiliations: 
2000 Duke University, Durham, NC 
Area:
Boronated Nucleic Acids
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"Kaizhang He"
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Barbara Ramsay Shaw grad student 2000 Duke
 (Synthesis and properties of boranophosphate nucleic acids.)

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Publications

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He K, Chou E, Begay S, et al. (2016) Conjugation and evaluation of triazole-linked single guide RNA for CRISPR-Cas9 gene editing. Chembiochem : a European Journal of Chemical Biology
Kelley ML, Strezoska Ž, He K, et al. (2016) Versatility of chemically synthesized guide RNAs for CRISPR-Cas9 genome editing. Journal of Biotechnology
Shaw BR, Dobrikov M, Wang X, et al. (2003) Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA. Annals of the New York Academy of Sciences. 1002: 12-29
Lato SM, Ozerova ND, He K, et al. (2002) Boron-containing aptamers to ATP. Nucleic Acids Research. 30: 1401-7
Shaw BR, Wan J, Wang X, et al. (2002) Reading and writing genetic information with boranophosphate (borane phosphate) mimics of nucleotides, DNA, and RNA Collection of Czechoslovak Chemical Communications. 5: 169-180
He K, Shaw BR. (2001) Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate. Bioorganic & Medicinal Chemistry Letters. 11: 615-7
Lin J, He K, Shaw BR. (2001) Novel 3',5'-cyclic nucleotide analogue: adenosine 3',5'-cyclic boranomonophosphate. Organic Letters. 3: 795-7
Lin J, He K, Shaw BR. (2001) Novel 3′,5′-cyclic nucleotide analogue: Adenosine 3′,5′-cyclic boranomonophosphate Organic Letters. 3: 795-797
Shaw BR, Sergueev D, He K, et al. (2000) Boranophosphate backbone: a mimic of phosphodiesters, phosphorothioates, and methyl phosphonates. Methods in Enzymology. 313: 226-57
Lin J, He K, Shaw BR. (2000) Synthesis of boron-containing ADP and GDP analogues: Nucleoside 5'-(Pα- boranodiphosphates) Helvetica Chimica Acta. 83: 1392-1397
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