Charles E. Dann, Ph.D.

Affiliations: 
2002 Johns Hopkins University, Baltimore, MD 
Area:
Molecular studies of signal transduction
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"Charles Dann"
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Daniel J. Leahy grad student 2002 Johns Hopkins
 (Structural studies of extracellular components of the Wnt signaling pathway.)
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Publications

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Dekhne AS, Shah K, Ducker GS, et al. (2019) Novel pyrrolo[3,2-d]pyrimidine compounds target mitochondrial and cytosolic one-carbon metabolism with broad-spectrum antitumor efficacy. Molecular Cancer Therapeutics
Ning C, Dekhne A, Nayeen MJ, et al. (2019) Abstract 4794: Targeting mitochondrial and cytosolic one carbon metabolism of pancreatic adenocarcinoma via the proton-coupled folate transporter with novel 5-substituted pyrrolo[3,2-d]pyrimidine analogs Cancer Research. 79: 4794-4794
Hughes AC, Subramanian S, Dann CE, et al. (2018) The C-terminal region of Bacillus subtilis SwrA is required for activity and adaptor-dependent LonA-proteolysis. Journal of Bacteriology
Subramanian S, Gao X, Dann CE, et al. (2017) MotI (DgrA) acts as a molecular clutch on the flagellar stator protein MotA in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America
Wang L, Wallace A, Raghavan S, et al. (2015) 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors. Journal of Medicinal Chemistry
Deis SM, Dann CE. (2015) Analysis of Antifolate Drugs with Disease Tissue Specificity Biophysical Journal. 108
Gao X, Dong X, Subramanian S, et al. (2014) Engineering of Bacillus subtilis strains to allow rapid characterization of heterologous diguanylate cyclases and phosphodiesterases. Applied and Environmental Microbiology. 80: 6167-74
Yin L, Dragnea V, Feldman G, et al. (2013) Redox and light control the heme-sensing activity of AppA. Mbio. 4: e00563-13
Wibowo AS, Singh M, Reeder KM, et al. (2013) Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proceedings of the National Academy of Sciences of the United States of America. 110: 15180-8
Gao X, Mukherjee S, Matthews PM, et al. (2013) Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway. Journal of Bacteriology. 195: 4782-92
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