Corey P. Causey, Ph.D.

2007 Duke University, Durham, NC 
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
"Corey Causey"
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Eric J. Toone grad student 2007 Duke
 (Expanding the synthetic utility of KDPG aldolase.)
Paul R. Thompson post-doc 2010 University of North Florida
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DuBose MB, Sartawi T, Sawatzky TM, et al. (2022) A peptoid-based inhibitor of Protein Arginine Methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells. The Journal of Biological Chemistry. 102205
Mann SA, DeMart MK, May B, et al. (2020) Histone H4-based peptoids are inhibitors of Protein Arginine Methyltransferase 1 (PRMT1). The Biochemical Journal
Mann SA, Salsburg A, Causey CP, et al. (2019) The development and characterization of a chemical probe targeting PRMT1 over PRMT5. Bioorganic & Medicinal Chemistry. 27: 224-229
Witalison EE, Cui X, Causey CP, et al. (2015) Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer. Oncotarget
Creech C, Kanaujia M, Causey CP. (2015) Synthesis and evaluation of 2-ethynyl-adenosine-5'-triphosphate as a chemical reporter for protein AMPylation. Organic & Biomolecular Chemistry. 13: 8550-5
Kholia S, Jorfi S, Thompson PR, et al. (2015) A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy. Journal of Extracellular Vesicles. 4: 26192
Marchenko M, Thomson A, Ellis TN, et al. (2015) Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases. Bioorganic & Medicinal Chemistry. 23: 2159-67
Witalison EE, Cui X, Hofseth AB, et al. (2015) Inhibiting protein arginine deiminases has antioxidant consequences. The Journal of Pharmacology and Experimental Therapeutics. 353: 64-70
Witalison EE, Cui X, Causey CP, et al. (2015) Abstract 238: Citrullination of miRNA regulators by PADs: A potential mechanism for the promotion of colitis and colitis-associated colorectal cancer Cancer Research. 75: 238-238
Thomson A, O'Connor S, Knuckley B, et al. (2014) Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases. Bioorganic & Medicinal Chemistry. 22: 4602-8
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