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Christopher M. Summa, Ph.D.

Affiliations: 
2002 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Organic Chemistry, Chemical Biology, De Novo Protein Design
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"Christopher Summa"
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William F. DeGrado grad student 2002 Penn
 (Computational methods and their applications for de novo functional protein design and membrane protein solubilization.)

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Ronchi VP, Kim ED, Summa CM, et al. (2017) In silico modeling of the cryptic E2~ubiquitin binding site of E6-associated Protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly. The Journal of Biological Chemistry
Chopra G, Summa CM, Levitt M. (2008) Solvent dramatically affects protein structure refinement. Proceedings of the National Academy of Sciences of the United States of America. 105: 20239-44
Summa CM, Levitt M. (2007) Near-native structure refinement using in vacuo energy minimization. Proceedings of the National Academy of Sciences of the United States of America. 104: 3177-82
Summa CM, Levitt M, Degrado WF. (2005) An atomic environment potential for use in protein structure prediction. Journal of Molecular Biology. 352: 986-1001
Slovic AM, Summa CM, Lear JD, et al. (2003) Computational design of a water-soluble analog of phospholamban. Protein Science : a Publication of the Protein Society. 12: 337-48
Summa CM, Rosenblatt MM, Hong JK, et al. (2002) Computational de novo design, and characterization of an A(2)B(2) diiron protein. Journal of Molecular Biology. 321: 923-38
North B, Summa CM, Ghirlanda G, et al. (2001) D(n)-symmetrical tertiary templates for the design of tubular proteins. Journal of Molecular Biology. 311: 1081-90
Lombardi A, Summa CM, Geremia S, et al. (2000) Retrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteins. Proceedings of the National Academy of Sciences of the United States of America. 97: 6298-305
DeGrado WF, Summa CM, Pavone V, et al. (1999) De novo design and structural characterization of proteins and metalloproteins. Annual Review of Biochemistry. 68: 779-819
Summa CM, Lombardi A, Lewis M, et al. (1999) Tertiary templates for the design of diiron proteins. Current Opinion in Structural Biology. 9: 500-8
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