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Duo Lu, Ph.D.

Affiliations: 
2009 University of Wisconsin, Madison, Madison, WI 
Area:
structure, DNA replication
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"Duo Lu"
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Parents

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James L. Keck grad student 2004-2009 UW Madison
 (Structural and mechanistic studies of Escherichia coli single-stranded DNA-binding protein interactions with genome maintenance enzymes.)

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Publications

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Guo J, Li N, Han J, et al. (2018) DNA recognition patterns of the multi-zinc-finger protein CTCF: a mutagenesis study. Acta Pharmaceutica Sinica. B. 8: 900-908
Sampson JN, Wheeler WA, Yeager M, et al. (2015) Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types. Journal of the National Cancer Institute. 107
Darbari VC, Lawton E, Lu D, et al. (2014) Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator Nucleic Acids Research. 42: 9249-9261
Lu D. (2013) [C2H2 zinc-finger recognition of biomolecules]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 48: 834-41
Lu D. (2012) Analyzing interactions between SSB and proteins by the use of fluorescence anisotropy. Methods in Molecular Biology (Clifton, N.J.). 922: 155-9
Lu D, Myers AR, George NP, et al. (2011) Mechanism of Exonuclease I stimulation by the single-stranded DNA-binding protein. Nucleic Acids Research. 39: 6536-45
Gruenig MC, Lu D, Won SJ, et al. (2011) Creating directed double-strand breaks with the Ref protein: a novel RecA-dependent nuclease from bacteriophage P1. The Journal of Biological Chemistry. 286: 8240-51
Lu D, Fillet S, Meng C, et al. (2010) Crystal structure of TtgV in complex with its DNA operator reveals a general model for cooperative DNA binding of tetrameric gene regulators. Genes & Development. 24: 2556-65
Lu D, Bernstein DA, Satyshur KA, et al. (2010) Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance. Proceedings of the National Academy of Sciences of the United States of America. 107: 633-8
Lu D, Windsor MA, Gellman SH, et al. (2009) Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. Biochemistry. 48: 6764-71
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