Michelle E. McCully, Ph.D.

Affiliations: 
2012 Bioengineering University of Washington, Seattle, Seattle, WA 
Area:
biophysics, protein dynamics, molecular dynamics simulations, amyloid
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Parents

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Valerie D. Daggett grad student 2012 University of Washington
 (The Dynamics and Folding Pathways of Naturally Occurring and Engineered Proteins at Atomic Resolution.)
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Publications

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Gonzalez NA, Li BA, McCully ME. (2022) The stability and dynamics of computationally designed proteins. Protein Engineering, Design & Selection : Peds. 35
Nguyen C, Yearwood LM, McCully ME. (2022) Thermostabilization mechanisms in thermophilic versus mesophilic three-helix bundle proteins. Journal of Computational Chemistry. 43: 197-205
Gill M, McCully ME. (2020) Molecular dynamics simulations suggest stabilizing mutations in a de novo designed α/β protein. Protein Engineering, Design & Selection : Peds
Ferreira PHB, Freitas FC, McCully ME, et al. (2020) The Role of Electrostatics and Folding Kinetics on the Thermostability of Homologous Cold Shock Proteins. Journal of Chemical Information and Modeling
Nguyen C, Yearwood LM, McCully ME. (2020) Comparing Stabilization Strategies Between Engineered and Naturally Thermostable Proteins Biophysical Journal. 118: 511a
Nguyen C, Young JT, Slade GG, et al. (2019) A Dynamic Hydrophobic Core and Surface Salt Bridges Thermostabilize a Designed Three-Helix Bundle. Biophysical Journal
Gonzalez N, Hamlin E, Khazi P, et al. (2019) A Structural, Dynamic, and Thermodynamic Explanation of Thermostability in a De Novo Designed Three-Helix Bundle Biophysical Journal. 116: 190a
Gianni S, McCully M, Malagrinò F, et al. (2018) A carboxylate to amide substitution tunes fold switching in a protein domain. Angewandte Chemie (International Ed. in English)
Hamlin EK, Chandu S, McCully ME. (2018) Folding Thermodynamics of a Three-Helix Bundle Protein and Its Engineered Thermostable Variant Biophysical Journal. 114: 54a
Young JT, Nguyen C, McCully ME. (2018) The Structural Basis of Thermostability in an Engineered Variant of the Engrailed Homeodomain Biophysical Journal. 114: 412a
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