Yue-Lei Chen

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
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"Yue-Lei Chen"
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Publications

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Damaneh MS, Hu JP, Huan XJ, et al. (2019) A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction. Investigational New Drugs
Chen YL, Zhang Y, Wang J, et al. (2019) A 17 gene panel for non-small cell lung cancer prognosis identified through integrative epigenomic-transcriptomic analyses of hypoxia-induced epithelial-mesenchymal transition. Molecular Oncology
Wei P, Liu B, Wang R, et al. (2019) Discovery of a series of dimethoxybenzene FGFR inhibitors with 5pyrrolo[2,3-]pyrazine scaffold: structure-activity relationship, crystal structural characterization and study. Acta Pharmaceutica Sinica. B. 9: 351-368
Wang X, Su M, Li Y, et al. (2019) Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor. Bioorganic & Medicinal Chemistry Letters
Liu T, Tang J, Liang J, et al. (2019) Stereoselective N-glycosylation with N4-acyl cytosines and efficient synthesis of gemcitabine Tetrahedron. 75: 1203-1213
Wang Q, Dai Y, Ji Y, et al. (2018) Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma. European Journal of Medicinal Chemistry. 163: 671-689
Hu J, Wang Y, Li Y, et al. (2018) Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups. European Journal of Medicinal Chemistry. 150: 156-175
Liu T, Zhu Z, Ren H, et al. (2018) Efficient syntheses of alpha- and beta-C-nucleosides and the origin of anomeric selectivity Organic Chemistry Frontiers. 5: 1992-1999
Liu T, Ren H, Li C, et al. (2018) Convenient preparation of pinometostat and related 5′-deoxy-5′-amino adenosine derivatives as well as their activity against DOT1L Tetrahedron Letters. 59: 415-417
Liu T, Xie W, Li C, et al. (2017) Preparation of 5'-deoxy-5'-amino-5'-C-methyl adenosine derivatives and their activity against DOT1L. Bioorganic & Medicinal Chemistry Letters
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