Yue-Lei Chen

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
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"Yue-Lei Chen"
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Publications

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Wang X, Su M, Li Y, et al. (2019) Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor. Bioorganic & Medicinal Chemistry Letters
Liu T, Xie W, Li C, et al. (2017) Preparation of 5'-deoxy-5'-amino-5'-C-methyl adenosine derivatives and their activity against DOT1L. Bioorganic & Medicinal Chemistry Letters
Kirby KA, Myshakina NA, Christen MT, et al. (2017) A 2-hydroxyisoquinoline-1,3-dione active site RNase H inhibitor binds in multiple modes to HIV-1 reverse transcriptase. Antimicrobial Agents and Chemotherapy
Hu J, Wang Y, Li Y, et al. (2017) Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor. European Journal of Medicinal Chemistry. 137: 176-195
Tang J, Vernekar SK, Chen YL, et al. (2017) Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase. European Journal of Medicinal Chemistry. 133: 85-96
Ren J, Xu W, Tang L, et al. (2016) Design and synthesis of benzylpiperidine inhibitors targeting the menin-MLL1 interface. Bioorganic & Medicinal Chemistry Letters
Tang L, Ren J, Ma Y, et al. (2016) Formation of 1,3-diazocine by palladium catalyzed C-H arylation Tetrahedron Letters
Ma Y, Sun G, Chen D, et al. (2015) Design and optimization of a series of 1-sulfonylpyrazolo[4,3-b]pyridines as selective c-Met inhibitors. Journal of Medicinal Chemistry. 58: 2513-29
Zhao L, Wang Y, Cao D, et al. (2015) Fragment-based drug discovery of 2-thiazolidinones as BRD4 inhibitors: 2. Structure-based optimization. Journal of Medicinal Chemistry. 58: 1281-97
Ren J, Yang M, Liu H, et al. (2015) Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienaymé reaction and their Hsp90 inhibitory activity. Organic & Biomolecular Chemistry. 13: 1531-5
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