Alan A. Chen, Ph.D.

Affiliations: 
2009 Washington University, Saint Louis, St. Louis, MO 
Area:
General Biophysics, Physical Chemistry, Biochemistry
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"Alan Chen"

Parents

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Rohit V. Pappu grad student 2009 Washington University
 (Non-idealities of strong 1:1 electrolytes and the mechanism of counterion specificity in a RNA kissing -loop complex.)
Angel E. Garcia post-doc 2009-2013 RPI

Children

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Srivathsan Vembanur Ranganathan post-doc 2014-2015 SUNY Albany (Chemistry Tree)
Paul M. Gasper post-doc 2014-2017 SUNY Albany (Chemistry Tree)
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Publications

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Nowzari ZR, Hale M, Ellis J, et al. (2024) Mutation of two intronic nucleotides alters RNA structure and dynamics inhibiting MBNL1 and RBFOX1 regulated splicing of the Insulin Receptor. Biorxiv : the Preprint Server For Biology
Hertz LM, White EN, Kuznedelov K, et al. (2023) The Effect of Pseudoknot Base Pairing on Cotranscriptional Structural Switching of the Fluoride Riboswitch. Biorxiv : the Preprint Server For Biology
Viegas RG, Sanches MN, Chen AA, et al. (2023) Characterizing the Folding Transition-State Ensembles in the Energy Landscape of an RNA Tetraloop. Journal of Chemical Information and Modeling
Abraham Punnoose J, Thomas KJ, Chandrasekaran AR, et al. (2023) High-throughput single-molecule quantification of individual base stacking energies in nucleic acids. Nature Communications. 14: 631
Mathivanan J, Bai Z, Chen A, et al. (2022) Design, Synthesis, and Characterization of a Novel 2'-5'-Linked Amikacin-Binding Aptamer: An Experimental and MD Simulation Study. Acs Chemical Biology. 17: 3478-3488
Cheng L, White EN, Brandt NL, et al. (2022) Cotranscriptional RNA strand exchange underlies the gene regulation mechanism in a purine-sensing transcriptional riboswitch. Nucleic Acids Research
D'Esposito RJ, Myers CA, Chen AA, et al. (2022) Challenges with Simulating Modified RNA: Insights into Role and Reciprocity of Experimental and Computational Approaches. Genes. 13
Yu AM, Gasper PM, Cheng L, et al. (2021) Computationally reconstructing cotranscriptional RNA folding from experimental data reveals rearrangement of non-native folding intermediates. Molecular Cell
Haruehanroengra P, Vangaveti S, Ranganathan SV, et al. (2020) Terpene Chain Length Affects the Base Pairing Discrimination of -geranyl-2-thiouridine in RNA Duplex. Iscience. 23: 101866
Chandrasekaran AR, Mathivanan J, Ebrahimi P, et al. (2020) Hybrid DNA/RNA nanostructures with 2'-5' linkages. Nanoscale
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