Lorraine S. Symington

Columbia University, New York, NY 
Genetics and biochemistry of DNA recombination and repair in yeast
"Lorraine Symington"
Mean distance: 4976.62 (cluster 32)


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Thomas D. Petes post-doc 1988 Chicago (Cell Biology Tree)


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Robert A. DeSimone research assistant 2006-2007 Cornell
Gary S. Fortin grad student 2004 Columbia
Allison P. Wheeler grad student 2004 Columbia
Lance D. Langston grad student 2005 Columbia
Cindy Fung grad student 2008 Columbia
Vanessa Marrero grad student 2010 Columbia
Christina Mott grad student 2010 Columbia
Eleni P. Mimitou grad student 2011 Columbia
Huan Chen grad student 2014 Columbia (Cell Biology Tree)
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Klein HL, Bačinskaja G, Che J, et al. (2019) Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell (Graz, Austria). 6: 1-64
Oh J, Symington LS. (2018) Role of the Mre11 Complex in Preserving Genome Integrity. Genes. 9
Oh J, Lee SJ, Rothstein R, et al. (2018) Xrs2 and Tel1 Independently Contribute to MR-Mediated DNA Tethering and Replisome Stability. Cell Reports. 25: 1681-1692.e4
Gnügge R, Oh J, Symington LS. (2018) Processing of DNA Double-Strand Breaks in Yeast. Methods in Enzymology. 600: 1-24
Ruff P, Donnianni RA, Glancy E, et al. (2016) RPA Stabilization of Single-Stranded DNA Is Critical for Break-Induced Replication. Cell Reports. 17: 3359-3368
Oh J, Al-Zain A, Cannavo E, et al. (2016) Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex. Molecular Cell
Deng SK, Yin Y, Petes TD, et al. (2015) Mre11-Sae2 and RPA Collaborate to Prevent Palindromic Gene Amplification. Molecular Cell. 60: 500-8
Sfeir A, Symington LS. (2015) Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway? Trends in Biochemical Sciences. 40: 701-14
Chen H, Donnianni RA, Handa N, et al. (2015) Sae2 promotes DNA damage resistance by removing the Mre11-Rad50-Xrs2 complex from DNA and attenuating Rad53 signaling. Proceedings of the National Academy of Sciences of the United States of America. 112: E1880-7
Deng SK, Chen H, Symington LS. (2015) Replication protein A prevents promiscuous annealing between short sequence homologies: Implications for genome integrity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 305-13
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