Patrick J. Loll
Affiliations: | 2001 | Pharmacology | University of Pennsylvania, Philadelphia, PA, United States |
| 2001- | Biochemistry & Molecular Biology | Drexel University College of Medicine, Philadelphia, PA, United States |
Area:
Protein crystallography, antibiotic resistanceWebsite:
http://drexel.edu/medicine/faculty/profiles/Patrick-Loll/Google:
"Patrick Loll"Bio:
https://www.researchgate.net/profile/Patrick_Loll
https://www.researchgate.net/publication/35646472_Crystallographic_studies_of_wild-type_and_mutant_forms_of_the_enzyme_staphylococcal_nuclease
DOI: 10.1002/prot.340050302
https://www.uchicagomedicine.org/forefront/news/aspirin-target-deciphered
Mean distance: 13271
Parents
Sign in to add mentor| Eaton Lattman | grad student | 1989 | Johns Hopkins (EduTree) | |
| (Crystallographic studies of wild-type and mutant forms of the enzyme staphylococcal nuclease.) | ||||
| R Michael Garavito | post-doc | 1989-1994 | Chicago | |
Children
Sign in to add trainee| Anthony E. Bevivino | grad student | 2001 | Penn |
| Kushol Gupta | grad student | 2003 | Penn |
| Nicoleta Economou | grad student | 2007-2012 | Drexel Medical School |
| Maya V Rao | grad student | 2012-2017 | Drexel Medical School |
| Elizabeth C. Upton | grad student | 2012-2018 | Drexel Medical School |
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Publications
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| Grasty KC, Guzik C, D'Lauro EJ, et al. (2023) Structure of VanS from Vancomycin-Resistant Enterococci: A Sensor Kinase with Weak ATP Binding. The Journal of Biological Chemistry. 103001 |
| Maciunas LJ, Porter N, Lee PJ, et al. (2021) Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states. Acta Crystallographica. Section D, Structural Biology. 77: 1027-1039 |
| Grasty KC, Weeks SD, Loll PJ. (2019) Structural insights into the activity and regulation of human Josephin-2. Journal of Structural Biology: X. 3: 100011 |
| Tronin AY, Maciunas LJ, Grasty KC, et al. (2019) Voltage-Dependent Profile Structures of a Kv-Channel via Time-Resolved Neutron Interferometry. Biophysical Journal |
| Jackson MR, Loll PJ, Jorns MS. (2019) X-Ray Structure of Human Sulfide:Quinone Oxidoreductase: Insights into the Mechanism of Mitochondrial Hydrogen Sulfide Oxidation. Structure (London, England : 1993) |
| Upton EC, Maciunas LJ, Loll PJ. (2019) Vancomycin does not affect the enzymatic activities of purified VanSA. Plos One. 14: e0210627 |
| Loll PJ. (2018) Structural Analysis of Anesthetics in Complex with Soluble Proteins. Methods in Enzymology. 603: 3-20 |
| Rao MV, Williams DR, Cocklin S, et al. (2017) Interaction between the AAA+ ATPase p97 and its cofactor ataxin3 in health and disease: Nucleotide-induced conformational changes regulate cofactor binding. The Journal of Biological Chemistry |
| Bonneté F, Loll PJ. (2017) Characterization of New Detergents and Detergent Mimetics by Scattering Techniques for Membrane Protein Crystallization. Methods in Molecular Biology (Clifton, N.J.). 1635: 169-193 |
| Woll KA, Peng W, Liang Q, et al. (2017) Photoaffinity ligand for the inhalational anesthetic sevoflurane allows mechanistic insight into potassium channel modulation. Acs Chemical Biology |