Jorge Capdevila
Affiliations: | Vanderbilt University, Nashville, TN |
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BiochemistryGoogle:
"Jorge Capdevila"Mean distance: 19906.5
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Publications
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| Capdevila JH, Falck JR. (2018) The Arachidonic Acid Monooxygenase. From Biochemical Curiosity to Physiological/Pathophysiological Significance. Journal of Lipid Research |
| Guo Z, Sevrioukova I, Hanse E, et al. (2016) Abstract 44: Hexyl-benzyl-biguanide (HBB) potently and selectively inhibits CYP3A4 epoxygenase activity and inhibits EET stabilization of mitochondrial respiration in ER+HER2- breast cancer cells, inducing glycolysis and pyruvate biosynthesis Cancer Research. 76: 44-44 |
| Falck JR, Koduru SR, Mohapatra S, et al. (2014) 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications. Journal of Medicinal Chemistry. 57: 6965-72 |
| Capdevila J, Wang W. (2013) Role of cytochrome P450 epoxygenase in regulating renal membrane transport and hypertension. Current Opinion in Nephrology and Hypertension. 22: 163-9 |
| Sun P, Antoun J, Lin DH, et al. (2012) Cyp2c44 epoxygenase is essential for preventing the renal sodium absorption during increasing dietary potassium intake. Hypertension. 59: 339-47 |
| Guo Z, Mitra R, Luo X, et al. (2012) Abstract 942: CYP3A4 epoxygenase mediates hypoxia-induced biosynthesis of epoxyeicosatrienoic acids (±)-11,12- and (±)-14,15-EET in breast cancer cells Cancer Research. 72: 942-942 |
| Mitra R, Guo Z, Milani M, et al. (2011) CYP3A4 mediates growth of estrogen receptor-positive breast cancer cells in part by inducing nuclear translocation of phospho-Stat3 through biosynthesis of (±)-14,15-epoxyeicosatrienoic acid (EET). The Journal of Biological Chemistry. 286: 17543-59 |
| Potter DA, Guo Z, Mitra R, et al. (2011) Abstract 357: CYP3A4 Activates Stat3 in ER + breast cancer Cancer Research. 71: 357-357 |
| HECKMANN B, MIOSKOWSKI C, LUMIN S, et al. (2010) ChemInform Abstract: Chiral Acetals: Stereocontrolled Syntheses of 16-, 17-, and 18- Hydroxyeicosatetraenoic Acids, Cytochrome P-450 Arachidonate Metabolites. Cheminform. 27: no-no |
| Chen JK, Chen J, Imig JD, et al. (2008) Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors. The Journal of Biological Chemistry. 283: 24514-24 |