Daniel E. Gottschling

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
Area:
cellular aging
Website:
http://labs.fhcrc.org/gottschling/
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"Daniel E. Gottschling"
Bio:

http://www.nasonline.org/member-directory/members/20024835.html

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SNBCP
Cross-listing: Telomere and Telomerase Tree

Parents

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Thomas R. Cech grad student 1984 CU Boulder
 (Chromatin structure and chromosomal function : Tetrahymena thermophila and Oxytricha nova as model systems)
Virginia A. Zakian post-doc Fred Hutchinson Cancer Center
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Publications

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Hughes AL, Hughes CE, Henderson KA, et al. (2016) Selective sorting and destruction of mitochondrial membrane proteins in aged yeast. Elife. 5
Thayer NH, Leverich CK, Fitzgibbon MP, et al. (2014) Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions. Proceedings of the National Academy of Sciences of the United States of America. 111: 14019-26
Dillin A, Gottschling DE, Nyström T. (2014) The good and the bad of being connected: the integrons of aging. Current Opinion in Cell Biology. 26: 107-12
Hughes AL, Gottschling DE. (2012) An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature. 492: 261-5
Gottschling DE. (2012) Molecular biology. Fragile delivery to the genome. Science (New York, N.Y.). 337: 160-1
Hotz M, Leisner C, Chen D, et al. (2012) Spindle pole bodies exploit the mitotic exit network in metaphase to drive their age-dependent segregation. Cell. 148: 958-72
Dymond JS, Richardson SM, Coombes CE, et al. (2011) Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature. 477: 471-6
Lindstrom DL, Leverich CK, Henderson KA, et al. (2011) Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. Plos Genetics. 7: e1002015
Rosenbaum JC, Fredrickson EK, Oeser ML, et al. (2011) Disorder targets misorder in nuclear quality control degradation: a disordered ubiquitin ligase directly recognizes its misfolded substrates. Molecular Cell. 41: 93-106
Verzijlbergen KF, Menendez-Benito V, van Welsem T, et al. (2010) Recombination-induced tag exchange to track old and new proteins. Proceedings of the National Academy of Sciences of the United States of America. 107: 64-8
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