M David Percival
Affiliations: | Concordia University (Canada), Montreal, QC, Canada | ||
| 2009- | Biochemistry and Molecular Biology | Merck Frosst Centre for Therapeutic Research |
Area:
BiochemistryGoogle:
"Michael David Percival" OR "M David Percival"Bio:
http://hdl.handle.net/2429/29058
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Parents
Sign in to add mentor| Stephen G. Withers | grad student | 1988 | UBC | |
| (Mechanistic studies on phosphoglucomutase.) | ||||
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Publications
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| Aspiotis R, Chen A, Cauchon E, et al. (2011) The discovery and synthesis of potent zwitterionic inhibitors of renin. Bioorganic & Medicinal Chemistry Letters. 21: 2430-6 |
| Léger S, Bayly CI, Black WC, et al. (2007) Primary amides as selective inhibitors of cathepsin K. Bioorganic & Medicinal Chemistry Letters. 17: 4328-32 |
| Black WC, Percival MD. (2006) The consequences of lysosomotropism on the design of selective cathepsin K inhibitors. Chembiochem : a European Journal of Chemical Biology. 7: 1525-35 |
| Ouellet M, Aitken SM, English AM, et al. (2004) Aromatic hydroxamic acids and hydrazides as inhibitors of the peroxidase activity of prostaglandin H2 synthase-2. Archives of Biochemistry and Biophysics. 431: 107-18 |
| Ouellet M, Falgueyret JP, Percival MD. (2004) Detergents profoundly affect inhibitor potencies against both cyclo-oxygenase isoforms. The Biochemical Journal. 377: 675-84 |
| Aitken SM, Ouellet M, Percival MD, et al. (2003) Mechanism of horseradish peroxidase inactivation by benzhydrazide: a critical evaluation of arylhydrazides as peroxidase inhibitors. The Biochemical Journal. 375: 613-21 |
| Ouellet M, Falgueyret JP, Ear PH, et al. (2002) Purification and characterization of recombinant microsomal prostaglandin E synthase-1. Protein Expression and Purification. 26: 489-95 |
| Aitken SM, Turnbull JL, Percival MD, et al. (2001) Thermodynamic analysis of the binding of aromatic hydroxamic acid analogues to ferric horseradish peroxidase. Biochemistry. 40: 13980-9 |
| Falgueyret JP, Oballa RM, Okamoto O, et al. (2001) Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. Journal of Medicinal Chemistry. 44: 94-104 |
| Forghani F, Ouellet M, Keen S, et al. (1998) Analysis of prostaglandin G/H synthase-2 inhibition using peroxidase-induced luminol luminescence. Analytical Biochemistry. 264: 216-21 |