S Meakin

The University of Western Ontario (Canada) 
Neuroscience Biology, Biochemistry
"S Meakin"
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Talebian A, Robinson-Brookes K, Meakin SO. (2018) TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1. Journal of Molecular Neuroscience : Mn. 67: 97-110
Wills MK, Keyvani Chahi A, Lau HR, et al. (2017) Signalling Adaptor ShcD Suppresses Erk Phosphorylation Distal to the Ret and Trk Neurotrophic Receptors. The Journal of Biological Chemistry
Li C, MacDonald JI, Talebian A, et al. (2016) Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells. Molecular and Cellular Biology
Zhou L, Talebian A, Meakin SO. (2015) The signaling adapter, FRS2, facilitates neuronal branching in primary cortical neurons via both Grb2- and Shp2-dependent mechanisms. Journal of Molecular Neuroscience : Mn. 55: 663-77
Geetha T, Rege SD, Mathews SE, et al. (2013) Nerve growth factor receptor TrkA, a new receptor in insulin signaling pathway in PC12 cells. The Journal of Biological Chemistry. 288: 23807-13
Talebian A, Robinson-Brookes K, MacDonald JI, et al. (2013) Ras guanine nucleotide releasing factor 1 (RasGrf1) enhancement of Trk receptor-mediated neurite outgrowth requires activation of both H-Ras and Rac. Journal of Molecular Neuroscience : Mn. 49: 38-51
Hryciw T, MacDonald JI, Phillips R, et al. (2010) The fibroblast growth factor receptor substrate 3 adapter is a developmentally regulated microtubule-associated protein expressed in migrating and differentiated neurons. Journal of Neurochemistry. 112: 924-39
Li C, Macdonald JI, Hryciw T, et al. (2010) Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells. Journal of Neurochemistry. 112: 882-99
Woronowicz A, Amith SR, Davis VW, et al. (2007) Trypanosome trans-sialidase mediates neuroprotection against oxidative stress, serum/glucose deprivation, and hypoxia-induced neurite retraction in Trk-expressing PC12 cells. Glycobiology. 17: 725-34
Dixon SJ, MacDonald JI, Robinson KN, et al. (2006) Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3. Biochimica Et Biophysica Acta. 1763: 366-80
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