Elzbieta A. Gryz, Ph.D.
Affiliations: | 2002 | The University of Western Ontario (Canada) |
Area:
Neuroscience Biology, BiochemistryGoogle:
"Elzbieta Gryz"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| S Meakin | grad student | 2002 | The University of Western Ontario (Canada) | |
| (The role of amino acid acidification of the activation loop tyrosines in the activation of the nerve growth factor receptor, TrkA.) | ||||
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Publications
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| Gryz EA, Meakin SO. (2003) Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-dependent, but not nerve growth factor-independent, differentiation and cell cycle arrest in the human neuroblastoma cell line, SY5Y. Oncogene. 22: 8774-85 |
| MacDonald JI, Gryz EA, Kubu CJ, et al. (2000) Direct binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkA. The Journal of Biological Chemistry. 275: 18225-33 |
| Gryz EA, Meakin SO. (2000) Acidic substitution of the activation loop tyrosines in TrkA supports nerve growth factor-independent cell survival and neuronal differentiation. Oncogene. 19: 417-30 |
| Meakin SO, MacDonald JI, Gryz EA, et al. (1999) The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation. The Journal of Biological Chemistry. 274: 9861-70 |
| Meakin SO, Gryz EA, MacDonald JI. (1997) A kinase insert isoform of rat TrkA supports nerve growth factor-dependent cell survival but not neurite outgrowth. Journal of Neurochemistry. 69: 954-67 |