Dominic C. Jaikaran, Ph.D.

Affiliations: 
2003 University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry
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"Dominic Jaikaran"
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Parents

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Andrew M. MacMillan grad student 2003 University of Toronto
 (Biochemical characterization of an RNA -editing enzyme.)
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Publications

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Pereira MJ, Nikolova EN, Hiley SL, et al. (2008) Single VS ribozyme molecules reveal dynamic and hierarchical folding toward catalysis. Journal of Molecular Biology. 382: 496-509
Jaikaran D, Smith MD, Mehdizadeh R, et al. (2008) An important role of G638 in the cis-cleavage reaction of the Neurospora VS ribozyme revealed by a novel nucleotide analog incorporation method. Rna (New York, N.Y.). 14: 938-49
Zamel R, Poon A, Jaikaran D, et al. (2004) Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme. Proceedings of the National Academy of Sciences of the United States of America. 101: 1467-72
Jaikaran DC, Collins CH, MacMillan AM. (2002) Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site. The Journal of Biological Chemistry. 277: 37624-9
Jaikaran DC, MacMillan AM. (2000) Template-directed interference footprinting for RNA based on inosine-specific cleavage. Bioorganic & Medicinal Chemistry Letters. 10: 1633-5
Jaikaran DC, Biggin PC, Wenschuh H, et al. (1997) Structure-function relationships in helix-bundle channels probed via total chemical synthesis of alamethicin dimers: effects of a Gln7 to Asn7 mutation. Biochemistry. 36: 13873-81
Woolley GA, Biggin PC, Schultz A, et al. (1997) Intrinsic rectification of ion flux in alamethicin channels: studies with an alamethicin dimer. Biophysical Journal. 73: 770-8
Foong LY, You S, Jaikaran DC, et al. (1997) Development of a novel thiol reagent for probing ion channel structure: studies in a model system. Biochemistry. 36: 1343-8
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