Voula Kanelis, Ph.D.

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry
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"Voula Kanelis"
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Daniela Rotin grad student 2001 University of Toronto
 (Characterization of Nedd4 WW domain - ENaC peptide interactions.)
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Publications

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Woloschuk RM, Reed PMM, Jaikaran ASI, et al. (2021) Structure-based design of a photoswitchable affibody scaffold. Protein Science : a Publication of the Protein Society
Bickers SC, Benlekbir S, Rubinstein JL, et al. (2021) Structure of Ycf1p reveals the transmembrane domain TMD0 and the regulatory region of ABCC transporters. Proceedings of the National Academy of Sciences of the United States of America. 118
Weiditch SA, Bickers SC, Bona D, et al. (2020) HK97 gp74 possesses an α-helical insertion in the ββα fold that affects its metal binding, cos site digestion, and activities. Journal of Bacteriology
Bickers SC, Sayewich JS, Kanelis V. (2020) Intrinsically disordered regions regulate the activities of ATP binding cassette transporters. Biochimica Et Biophysica Acta. Biomembranes. 183202
Weiditch SA, Seraphim TV, Houry WA, et al. (2019) Strategies for purification of the bacteriophage HK97 small and large terminase subunits that yield pure and homogeneous samples that are functional. Protein Expression and Purification. 160: 45-55
Sooklal CR, Lopez-Alonso JP, Papp N, et al. (2018) Phosphorylation alters the residual structure and interactions of the regulatory L1 linker connecting NBD1 to the membrane-bound domain in SUR2B. Biochemistry
Zhao J, Beyrakhova K, Liu Y, et al. (2017) Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. Plos Pathogens. 13: e1006394
Alvarez CP, Stagljar M, Muhandiram DR, et al. (2017) Hyperinsulinism-causing mutations cause multiple molecular defects in SUR1 NBD1. Biochemistry
de Araujo ED, Alvarez CP, López-Alonso JP, et al. (2015) Phosphorylation-dependent changes in nucleotide binding, conformation, and dynamics of the first nucleotide binding domain (NBD1) of the sulfonylurea receptor 2B (SUR2B). The Journal of Biological Chemistry. 290: 22699-714
de Araujo ED, Kanelis V. (2014) Successful development and use of a thermodynamic stability screen for optimizing the yield of nucleotide binding domains. Protein Expression and Purification. 103: 38-47
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