Shawn D. Spencer, Ph.D.
Affiliations: | 2004 | Temple University, Philadelphia, PA, United States |
Area:
Pharmaceutical Chemistry, BiochemistryGoogle:
"Shawn Spencer"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Robert Raffa | grad student | 2004 | Temple University | |
| (Comparison of free vs. immobilized RNase -A kinetics and binding thermodynamics of a pyrimidine nucleotide using isothermal titration calorimetry.) | ||||
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Publications
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| Udofot O, Jaruszewski K, Spencer S, et al. (2014) Development of a novel approach to enhance the solubility of ftibamzone formulation. Integrative Molecular Medicine. 1: 61-66 |
| Spencer SD, Rosen LS, Gordon MS, et al. (2014) Abstract CT222: Differences in pharmacokinetics of TRC105 (anti-endoglin antibody) when administered as a single agent versus in combination with bevacizumab (Bev) Cancer Research. 74 |
| Gordon MS, Rosen LS, Mendelson D, et al. (2013) A phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors. Investigational New Drugs. 31: 714-23 |
| Wang XY, He ZC, Song LY, et al. (2011) Chemotherapeutic effects of bioassay-guided extracts of the American cockroach, Periplaneta americana. Integrative Cancer Therapies. 10: NP12-23 |
| Spencer SD, Raffa RB. (2004) Isothermal titration calorimetric study of RNase-A kinetics (cCMP --> 3'-CMP) involving end-product inhibition. Pharmaceutical Research. 21: 1642-7 |
| Raffa RB, Stagliano GW, Spencer SD. (2004) Protonation effect on drug affinity. European Journal of Pharmacology. 483: 323-4 |
| Raffa RB, Spencer SD, Schulingkamp RJ. (2002) Toward RNase inhibitors: thermodynamics of 2'-CMP/RNase-A binding in multi-ion buffer. Biochemical Pharmacology. 63: 1937-9 |
| Spencer SD, Abdul O, Schulingkamp RJ, et al. (2002) Toward the design of ribonuclease (RNase) inhibitors: ion effects on the thermodynamics of binding of 2'-CMP to RNase A. The Journal of Pharmacology and Experimental Therapeutics. 301: 925-9 |