Peter A. Keyel, Ph.D.

Affiliations: 
2006 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Cell Biology, Biochemistry
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Linton Traub grad student 2006 University of Pittsburgh
 (Dynamics and cargo selectivity of endocytic adaptor proteins.)
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Publications

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Ray S, Thapa R, Keyel PA. (2018) Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins. Toxins. 11
Romero M, Keyel M, Shi G, et al. (2017) Intrinsic repair protects cells from pore-forming toxins by microvesicle shedding. Cell Death and Differentiation
Sun C, Heid ME, Keyel PA, et al. (2013) The second transmembrane domain of P2X7 contributes to dilated pore formation. Plos One. 8: e61886
Keyel PA, Heid ME, Watkins SC, et al. (2012) Visualization of bacterial toxin induced responses using live cell fluorescence microscopy. Journal of Visualized Experiments : Jove. e4227
Keyel PA, Tkacheva OA, Larregina AT, et al. (2012) Coordinate stimulation of macrophages by microparticles and TLR ligands induces foam cell formation. Journal of Immunology (Baltimore, Md. : 1950). 189: 4621-9
Keyel PA, Loultcheva L, Roth R, et al. (2011) Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane. Journal of Cell Science. 124: 2414-23
Keyel PA, Thieman JR, Roth R, et al. (2008) The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis. Molecular Biology of the Cell. 19: 5309-26
Keyel PA, Mishra SK, Roth R, et al. (2006) A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors. Molecular Biology of the Cell. 17: 4300-17
Edeling MA, Mishra SK, Keyel PA, et al. (2006) Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly. Developmental Cell. 10: 329-42
Hawryluk MJ, Keyel PA, Mishra SK, et al. (2006) Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein. Traffic (Copenhagen, Denmark). 7: 262-81
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