Laurence H. Hurley
Affiliations: | Biochemistry | University of Arizona, Tucson, AZ |
Area:
Molecular Biology, Pharmaceutical Chemistry, General BiophysicsWebsite:
https://www.pharmacy.arizona.edu/directory/profile/laurence-hurley-phdGoogle:
"Laurence Hurley"Bio:
https://pubs.rsc.org/en/content/articlelanding/1969/c2/c29690000245#!divAbstract
Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Heinz G. Floss | grad student | 1970 | Purdue | |
| (Biosynthesis of the antibiotic indolmycin by Streptomyces griseus) | ||||
Children
Sign in to add trainee| Cory L. Grand | grad student | 2003 | University of Arizona |
| Steven L. Warner | grad student | 2005 | University of Arizona |
| Thomas S. Dexheimer | grad student | 2006 | University of Arizona |
| Chandana Sharma | grad student | 2006 | University of Arizona |
| Justin D. Dietrich | grad student | 2008 | University of Arizona |
| Kexiao Guo | grad student | 2008 | University of Arizona |
| SunMi L. Palumbo | grad student | 2009 | University of Arizona |
| Samantha L. Kendrick | grad student | 2010 | University of Arizona |
| Jessica S. Fortin | grad student | 2008-2010 | University of Arizona |
| Reena Chawla | post-doc | 2015- | University of Arizona |
| Anuj Sharma | post-doc | 2007-2010 | University of Arizona |
| Richard T Wheelhouse | research scientist | UT Austin |
BETA: Related publications
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Publications
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| Xu H, Hurley LH. (2022) A First-in-Class Clinical G-Quadruplex-Targeting Drug. The Bench-to-Bedside Translation of the Fluoroquinolone QQ58 to CX-5461 (Pidnarulex). Bioorganic & Medicinal Chemistry Letters. 129016 |
| King JJ, Irving KL, Evans CW, et al. (2020) DNA G-Quadruplex and i-Motif Structure Formation Is Interdependent in Human Cells. Journal of the American Chemical Society |
| Miranti CK, Moore S, Kim Y, et al. (2020) Erratum: Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex. Oncotarget. 11: 2586 |
| Miranti CK, Moore S, Kim Y, et al. (2020) Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex. Oncotarget. 11: 1758-1776 |
| Montoya JJ, Turnidge MA, Wai DH, et al. (2019) In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells. Bmc Cancer. 19: 1251 |
| Toshniwal P, Nguyen M, Guédin A, et al. (2019) TGF-β-induced fibrotic stress increases G-quadruplex formation in human fibroblasts. Febs Letters |
| Song JH, Kang HJ, Luevano LA, et al. (2019) Small-Molecule-Targeting Hairpin Loop of hTERT Promoter G-Quadruplex Induces Cancer Cell Death. Cell Chemical Biology |
| Ferdosi SR, Bollam S, Peng S, et al. (2019) Abstract 5226: Non-canonical functions of TERT in glioblastoma pathobiology Cancer Research. 79: 5226-5226 |
| Ferdosi S, Taylor B, Bollam S, et al. (2019) CBMT-23. NON-CANONICAL FUNCTIONS OF TERT IN GLIOBLASTOMA Neuro-Oncology. 21: vi38-vi38 |
| Ho D, Kretzmann JA, Norret M, et al. (2018) Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA. Nature Nanotechnology |